Active-Mono-Sulfone-PEG8-acid
- CAS No.
- 2055048-45-6
- Chemical Name:
- Active-Mono-Sulfone-PEG8-acid
- Synonyms
- Active-mono-sulfone-peg8-cid;Active-Mono-Sulfone-PEG8-acid;Propanoic acid, 3-[[25-[4-[2-[[(4-methylphenyl)sulfonyl]methyl]-1-oxo-2-propen-1-yl]phenyl]-25-oxo-3,6,9,12,15,18,21-heptaoxa-24-azapentacos-1-yl]oxy]-
- CBNumber:
- CB33363840
- Molecular Formula:
- C37H53NO14S
- Molecular Weight:
- 767.88
- MDL Number:
- MFCD30458030
- MOL File:
- 2055048-45-6.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P280-P305+P351+P338 |
Active-Mono-Sulfone-PEG8-acid price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | FHD04845 | Active-mono-sulfone-PEG8-cid | 2055048-45-6 | 5mg | $900 | 2026-06-04 | Buy |
| Biosynth | FHD04845 | Active-mono-sulfone-PEG8-cid | 2055048-45-6 | 50mg | $900 | 2026-06-04 | Buy |
| Biosynth | FHD04845 | Active-mono-sulfone-PEG8-cid | 2055048-45-6 | 25mg | $900 | 2026-06-04 | Buy |
| Biosynth | FHD04845 | Active-mono-sulfone-PEG8-cid | 2055048-45-6 | 10mg | $900 | 2026-06-04 | Buy |
| Biosynth | FHD04845 | Active-mono-sulfone-PEG8-cid | 2055048-45-6 | 100mg | $1298 | 2026-06-04 | Buy |
Active-Mono-Sulfone-PEG8-acid Chemical Properties, Uses, Production
Description
Active-Mono-Sulfone-PEG8-acid is a PEG linker with a sulfone and acid end group. The sulfone group can be conjugated with thiol groups of proteins. The terminal carboxylic acid can react with primary amines in the presence of activators such as EDC and HATU to from stable amide bonds. The hydrophilic PEG chain increases the water solubility of the compound in aqueous media.
Uses
Active-mono-sulfone-PEG8-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Active-Mono-Sulfone-PEG8-acid Preparation Products And Raw materials
Raw materials
Preparation Products
Active-Mono-Sulfone-PEG8-acid Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Jinan elephant international trading co., LTD | 13006575422@163.com | China | 6347 | 58 | |
| Xi'an Confluore Biological Technology Co., Ltd. | +86-156-80926068 +86-15680926068 | 1924344760@qq.com | China | 4229 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Shaanxi Xinyan Bomei Biotechnology Co., Ltd. | 13892832556 | 2440688701@qq.com | China | 1978 | 58 |
| Zhengzhou Akem Chemical Co., Ltd | 13303867194 | 770406999@qq.com | China | 9949 | 58 |
| Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd | 0431-80514535 19917294565 | et@chemextension.com | China | 5061 | 58 |
| Jilin Chinese Academy of Sciences-yanshen Technology | 18143011203 | ET-market@chemextension.com | China | 38906 | 58 |
| Shandong Dayou Pharmaceutical Research and Development Co., Ltd. | hanfangpharma@126.com 15165037910 | hanfangpharma@126.com | China | 25800 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29874 | 58 |
| Henan Mengtai Pharmaceutical Technology Co., Ltd | 17634413542 | 1959525201@qq.com | China | 9011 | 58 |
View Latest Price from Active-Mono-Sulfone-PEG8-acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-06-07 | Active-Mono-Sulfone-PEG8-acid
2055048-45-6
|
100mg | >98.00% | 100mg | Xian confluore Biological Technology Co., Ltd. |
-
- Active-Mono-Sulfone-PEG8-acid
2055048-45-6
- $0.00
- >98.00%
- Xian confluore Biological Technology Co., Ltd.
