QGOICCMBEDDFCI-NXQGQTBASA-N
- CAS No.
- 1623432-51-8
- Chemical Name:
- QGOICCMBEDDFCI-NXQGQTBASA-N
- Synonyms
- AM-7209;AMG7209;AMG-7209;AMG 7209;QGOICCMBEDDFCI-NXQGQTBASA-N;Benzoic acid, 4-[[2-[(3R,5R,6S)-6-(4-chloro-3-fluorophenyl)-5-(3-chlorophenyl)-1-[(1S)-1-cyclopropyl-2-[(1,1-dimethylethyl)sulfonyl]ethyl]-3-methyl-2-oxo-3-piperidinyl]acetyl]amino]-2-methoxy-
- CBNumber:
- CB33408750
- Molecular Formula:
- C37H41Cl2FN2O7S
- Molecular Weight:
- 747.7
- MDL Number:
- MFCD28902225
- MOL File:
- 1623432-51-8.mol
- MSDS File:
- SDS
QGOICCMBEDDFCI-NXQGQTBASA-N Chemical Properties, Uses, Production
Description
AMG-7209 is a potent and selective inhibitor of the MDM2-p53 interaction.
Uses
AM-7209 is a potent and selective MDM2-p53 interaction inhibitor with a Kd of 38 pM. AM-7209 inhibits the MDM2 amplified SJSA-1 osteosarcoma cell line with an IC50 of 1.6 nM. AM-7209 shows antitumor activities[1].
References
[1] Yosup Rew, et al. Discovery of AM-7209, a potent and selective 4-amidobenzoic acid inhibitor of the MDM2-p53 interaction. J Med Chem. 2014 Dec 26;57(24):10499-511. DOI:10.1021/jm501550p
QGOICCMBEDDFCI-NXQGQTBASA-N Preparation Products And Raw materials
QGOICCMBEDDFCI-NXQGQTBASA-N Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6288 | 58 |
| Nanjing Shizhou Biology Technology Co.,Ltd | 025-85560043 15850508050 | cindy.huang@synzest.com | China | 11975 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29874 | 58 |
| Supplier | Advantage |
|---|---|
| TargetMol Chemicals Inc. | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 58 |
| Nanjing Shizhou Biology Technology Co.,Ltd | 58 |
| TargetMol Chemicals Inc. | 58 |
