MONOSIALOGANGLIOSIDE GM3
- CAS No.
- 54827-14-4
- Chemical Name:
- MONOSIALOGANGLIOSIDE GM3
- Synonyms
- Ganglioside GM3;Ganglioside GM3 (d18:1/18:0);Ganglioside GM3 (d18:1/20:0);Ganglioside GM3 (d18:1/22:0);Ganglioside GM3 (d18:1/24:0);Ganglioside GM3 (d18:1/25:0);Ganglioside GM3 (d18:1/26:0);Ganglioside GM3 (d18:1/12:0);Ganglioside GM3 (d18:1/16:0);Ganglioside GM3 (d18:1/24:1(15Z))
- CBNumber:
- CB3344558
- Molecular Formula:
- C64H118N2O21.H3N
- Molecular Weight:
- 1268.66
- MDL Number:
- MFCD00131139
- MOL File:
- 54827-14-4.mol
- MSDS File:
- SDS
- TDS File:
- TDS
MONOSIALOGANGLIOSIDE GM3 price More Price(20)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | G5642 | Monosialoganglioside GM3 from canine blood ≥98%, lyophilized powder | 54827-14-4 | 0.5mg | $540 | 2026-04-30 | Buy |
| Sigma-Aldrich | G5642 | Monosialoganglioside GM3 from canine blood ≥98% | 54827-14-4 | 1mg | $886 | 2026-04-30 | Buy |
| Cayman Chemical | 31711 | Ganglioside GM3 (bovine buttermilk) (ammonium salt) ≥98% | 54827-14-4 | 1mg | $236 | 2026-04-30 | Buy |
| Cayman Chemical | 31711 | Ganglioside GM3 (bovine buttermilk) (ammonium salt) ≥98% | 54827-14-4 | 5mg | $1036 | 2026-04-30 | Buy |
| Cayman Chemical | 15587 | Ganglioside GM3 (bovine brain) (sodium salt) ≥98% | 54827-14-4 | 1mg | $262 | 2026-04-30 | Buy |
MONOSIALOGANGLIOSIDE GM3 Chemical Properties, Uses, Production
Uses
Monosialoganglioside GM3 can have anti-tumor effects by regulating cell apoptosis, angiogenesis. Monosialoganglioside GM3 can also regulate peripheral insulin receptor signaling and increases in GM3 in adipose tissue of obese humans may contribute to insulin resistance.
Uses
Monosialoganglioside GM3 from canine blood has been used as a reference standard in high-performance thin-layer chromatography (HPTLC) to analyze ganglioside signatures of prostate cancer (CaP) cells. It has also been used to determine ganglioside-binding profiles of methylotrophic yeast (Pichia pastoris) secreted cholera toxin B subunit (PpCTB) by enzyme-linked immunosorbent assay (ELISA).
General Description
Gangliosides are major constituents of neuronal cell membranes and endoplasmic reticulum. They contain a sialated polysaccharide chain linked to ceramide through a β-glycosidic linkage. For classification of gangliosides see Svennerholm, L., et al. (eds.), Structure and Function of Gangliosides, New York, Plenum, 1980.
Biochem/physiol Actions
Monosialoganglioside GM3 has a potential role in cancer development and progression. Increased expression of GM3 has been observed in various types of cancer. Hence, it is used as a tumor-associated carbohydrate antigen during cancer vaccine development.
MONOSIALOGANGLIOSIDE GM3 Preparation Products And Raw materials
Raw materials
Preparation Products
MONOSIALOGANGLIOSIDE GM3 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Spectrum Chemical Manufacturing Corp. | 021-021-021-67601398-809-809-809 15221380277 | marketing_china@spectrumchemical.com | China | 9643 | 60 |
| Shanghai Tauto Biotech Co., Ltd. | 021-51320588 | tauto@tautobiotech.com | China | 3984 | 66 |
| Yichang Zhongyitai Trading Co., Ltd. | 0717-6449896 13886658719 | root@zhongyitai.com | China | 1978 | 58 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51389 | 80 |
| Alfa Chemistry | 1-516-6625404 | support@alfa-chemistry.com | United States | 9170 | 60 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9799 | 58 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 400-920-5774 | sales@glpbio.cn | China | 6705 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +86-13203830695 | laboratory@coreychem.com | China | 30203 | 58 |
| BOC Sciences | 16314854226 | inquiry@bocsci.com | United States | 9713 | 58 |
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