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ChemicalBook >> CAS DataBase List >>15(R)-17-Phenyl trinor prostaglandin f2alpha isopropyl ester

15(R)-17-Phenyl trinor prostaglandin f2alpha isopropyl ester

15(R)-17-Phenyl trinor prostaglandin f2alpha isopropyl ester Structure
15(R)-17-Phenyl trinor prostaglandin f2alpha isopropyl ester structure
CAS No.
130273-87-9
Chemical Name:
15(R)-17-Phenyl trinor prostaglandin f2alpha isopropyl ester
Synonyms
17-phenyl trinor PGF2α-iPr;JGZRPRSJSQLFBO-DYZSFVSISA-N;15(R)-Bimatoprost isopropyl ester;15-epi Bimatoprost isopropyl ester;17-phenyl trinor PGF2α isopropyl ester;Bimatoprost Acid 15-Epi Isopropyl Ester;15(R)-17-phenyl trinor Prostaglandin F2α isopropyl ester;15(R)-17-Phenyl trinor prostaglandin f2alpha isopropyl ester;BIMATOPROST ISOPROPYL ESTER/7-[(1R,2R,3R,5S)-3,5-DIHYDROXY-2-[(1E,3R)-3-HYDROXY-5-PHENYL-1-PENTEN-1-;9ALPHA,11ALPHA,15R-TRIHYDROXY-17-PHENYL-18,19,20-TRINOR-PROSTA-5Z,13E-DIEN-1-OIC ACID, ISOPROPYL ESTER
CBNumber:
CB3350896
Molecular Formula:
C26H38O5
Molecular Weight:
430.58
MDL Number:
MFCD05863953
MOL File:
130273-87-9.mol
MSDS File:
SDS
Last updated:2026-09-12 18:52:00
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15(R)-17-Phenyl trinor prostaglandin f2alpha isopropyl ester Properties

storage temp. Store at -20°C
solubility DMF:30.0(Max Conc. mg/mL);69.67(Max Conc. mM)
Ethanol:30.0(Max Conc. mg/mL);69.67(Max Conc. mM)
PBS (pH 7.2):1.0(Max Conc. mg/mL);2.32(Max Conc. mM)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Flame (GHS02)Exclamation Mark (GHS07)Health Hazard (GHS08)
GHS02,GHS07,GHS08
Signal word  Danger
Hazard statements  H225-H319-H360-H336
Precautionary statements  P201-P202-P210-P240-P241-P242-P243-P261-P264-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P308+P313-P312-P337+P313-P370+P378-P403+P233-P403+P235-P405-P501
NFPA 704
3
2 0

15(R)-17-Phenyl trinor prostaglandin f2alpha isopropyl ester price More Price(12)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 16825 15(R)-17-phenyl trinor Prostaglandin F2α isopropyl ester ≥98% 130273-87-9 1mg $81 2026-04-30 Buy
Cayman Chemical 16825 15(R)-17-phenyl trinor Prostaglandin F2α isopropyl ester ≥98% 130273-87-9 5mg $357 2026-04-30 Buy
Cayman Chemical 16825 15(R)-17-phenyl trinor Prostaglandin F2α isopropyl ester ≥98% 130273-87-9 10mg $633 2026-04-30 Buy
Cayman Chemical 16825 15(R)-17-phenyl trinor Prostaglandin F2α isopropyl ester ≥98% 130273-87-9 50mg $2756 2026-04-30 Buy
ChemScene CS-0064249 Bimatoprost isopropyl ester 130273-87-9 1mg $174 2026-06-04 Buy
Product number Packaging Price Buy
16825 1mg $81 Buy
16825 5mg $357 Buy
16825 10mg $633 Buy
16825 50mg $2756 Buy
CS-0064249 1mg $174 Buy

15(R)-17-Phenyl trinor prostaglandin f2alpha isopropyl ester Chemical Properties, Uses, Production

Description

15(R)-17-phenyl trinor Prostaglandin F2α isopropyl ester (15(R)-17-phenyl trinor PGF2α isopropyl ester) is the latanoprost-related isomer containing both a double bond at 13,14 and an inverted (β) hydroxyl group at C-15. Similar to 15(S)-latanoprost, 15(R)-17-phenyl trinor PGF2α isopropyl ester is a potential impurity in most commercial preparations of the latanoprost bulk drug product. The IC50 values for the free acid forms of 15(S)-17-phenyl trinor PGF2α and 15(R)-17-phenyl trinor PGF2α were determined to be 0.71 nM and 30 nM, respectively, in a FP receptor binding assay using the cat iris sphincter muscle. A 3 μg dose of 15(R)-17-phenyl trinor PGF2α caused a 1.9 mmHg reduction of IOP in normotensive cynomolgus monkeys.

Uses

15(R)-17-phenyl trinor Prostaglandin F2α isopropyl ester (15(R)-17-phenyl trinor PGF2α isopropyl ester) is the latanoprost-related isomer containing both a double bond at 13,14 and an inverted (β) hydroxyl group at C-15. Similar to 15(S)-latanoprost, 15(R)-17-phenyl trinor PGF2α isopropyl ester is a potential impurity in most commercial preparations of the latanoprost bulk drug product. The IC50 values for the free acid forms of 15(S)-17-phenyl trinor PGF2α and 15(R)-17-phenyl trinor PGF2α were determined to be 0.71 nM and 30 nM, respectively, in a FP receptor binding assay using the cat iris sphincter muscle.1 A 3 μg dose of 15(R)-17-phenyl trinor PGF2α caused a 1.9 mmHg reduction of IOP in normotensive cynomolgus monkeys.

References

[1] Resul, et al. Phenyl-substituted prostaglandins: Potent and selective antiglaucoma agents. J. Med. Chem. 36(2), 243-248 (1993).

15(R)-17-Phenyl trinor prostaglandin f2alpha isopropyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

15(R)-17-Phenyl trinor prostaglandin f2alpha isopropyl ester Suppliers

Global Suppliers ( 23)
Supplier Tel Email Country ProdList Advantage
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 400-920-5774 sales@glpbio.cn China 6705 58
Shanghai Fuyi Biological Technology Co., Ltd. 18096642264;18096409024 sales@foreversyn.com China 492 58
BOC Sciences 16314854226; +8616314854226 inquiry@bocsci.com United States 19852 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
sgtlifesciences pvt ltd +91-8790379245 dj@sgtlifesciences.com China 12351 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11123 58
Nanjing Shizhou Biology Technology Co.,Ltd 025-85560043 13675144456 sean.lv@synzest.com China 11432 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11963 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29874 58
TargetMol Chemicals Inc. +1-781-999-5354; support@targetmol.com United States 38999 58
Supplier Advantage
Shanghai Hongye Biotechnology Co. Ltd 58
Shanghai Fuyi Biological Technology Co., Ltd. 58
BOC Sciences 58
TargetMol Chemicals Inc. 58
sgtlifesciences pvt ltd 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58
Nanjing Shizhou Biology Technology Co.,Ltd 58
Shanghai Yifei Biotechnology Co. , Ltd. 58
TargetMol Chemicals Inc. 58
TargetMol Chemicals Inc. 58

View Latest Price from 15(R)-17-Phenyl trinor prostaglandin f2alpha isopropyl ester manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Bimatoprost isopropyl ester pictures 2026-05-11 Bimatoprost isopropyl ester
130273-87-9
 $265.00-1980.00 10g TargetMol Chemicals Inc.

130273-87-9 (15(R)-17-Phenyl trinor prostaglandin f2alpha isopropyl ester) Related Search:

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17-phenoxy trinor Prostaglandin F2α isopropyl ester

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15(R)-17-phenyl trinor Prostaglandin F2α isopropyl ester 15(R)-Bimatoprost isopropyl ester JGZRPRSJSQLFBO-DYZSFVSISA-N 15-epi Bimatoprost isopropyl ester 9ALPHA,11ALPHA,15R-TRIHYDROXY-17-PHENYL-18,19,20-TRINOR-PROSTA-5Z,13E-DIEN-1-OIC ACID, ISOPROPYL ESTER BIMATOPROST ISOPROPYL ESTER/7-[(1R,2R,3R,5S)-3,5-DIHYDROXY-2-[(1E,3R)-3-HYDROXY-5-PHENYL-1-PENTEN-1- Bimatoprost Isopropyl Ester/7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3R)-3-Hydroxy-5-Phenyl-1-Penten-1-Yl]Cyclopentyl]-(5Z)-5-Heptenoic Acid 1-Methylethyl Ester Bimatoprost Acid 15-Epi Isopropyl Ester 5-Heptenoic acid, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3R)-3-hydroxy-5-phenyl-1-penten-1-yl]cyclopentyl]-, 1-methylethyl ester, (5Z)- Isopropyl (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((R,E)-3-hydroxy-5-phenylpent-1-en-1-yl)cyclopentyl)hept-5-enoate 17-phenyl trinor PGF2α isopropyl ester 17-phenyl trinor PGF2α-iPr Propan-2-yl (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2- [(E,3R)-3-hydroxy-5-phenylpent-1- enyl]cyclopentyl]hept-5-enoate 15(R)-17-Phenyl trinor prostaglandin f2alpha isopropyl ester 130273-87-9