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Thiazolyl Blue

Thiazolyl Blue Structure
Thiazolyl Blue structure
CAS No.
298-93-1
Chemical Name:
Thiazolyl Blue
Synonyms
MTT;THIAZOLYL BLUE TETRAZOLIUM BROMIDE;3-(4,5-DIMETHYL-2-THIAZOLYL)-2,5-DIPHENYLTETRAZOLIUM BROMIDE;METHYLTHIAZOLETETRAZOLIUM;METHYLTHIAZOLETETRAZOLIUM (MTT);MTT - CAS 298-93-1 - Calbiochem;THIAZOYL BLUE TETRAZOLIUM BROMIDE;METHYLTHIAZOLYLDIPHENYL-TETRAZOLIUM BROMIDE;2-(4,5-dimethyl-2-thiazolyl)-3,5-diphenyl-2h-tetrazoliubromide;3-(4,5-DIMETHYL-2-THIAZOLYL)-2,5-DIPHENYL-2H-TETRAZOLIUM BROMIDE
CBNumber:
CB3383104
Molecular Formula:
C18H16N5S.Br
Molecular Weight:
414.32
MDL Number:
MFCD00011964
MOL File:
298-93-1.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-08-20 20:20:01
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Thiazolyl Blue Properties

Melting point 195 °C (dec.) (lit.)
Density 1.4886 (estimate)
storage temp. 2-8°C
solubility methanol: 5 mg/mL, clear
form powder
color Yellow to orange
Water Solubility Slightly soluble.Clear yellow solution at 5mg in 1ml of water on vortexing
Sensitive Light Sensitive
λmax 378 nm, 242 nm
BRN 3825277
Stability Hygroscopic
Major Application diagnostic assay manufacturing
hematology
histology
Biological Applications Cell viability assay; microbial growth assays; DNA quantification assays; tissue viability assays; detecting enzymes; measuring membrane potential; treating Alzheimer’s disease,asthma,cancer
InChI 1S/C18H16N5S.BrH/c1-13-14(2)24-18(19-13)23-21-17(15-9-5-3-6-10-15)20-22(23)16-11-7-4-8-12-16;/h3-12H,1-2H3;1H/q+1;/p-1
InChIKey AZKSAVLVSZKNRD-UHFFFAOYSA-M
SMILES [Br-].Cc1nc(sc1C)-[n+]2nc(nn2-c3ccccc3)-c4ccccc4
CAS DataBase Reference 298-93-1(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII EUY85H477I
EPA Substance Registry System 2H-Tetrazolium, 2-(4,5-dimethyl-2-thiazolyl)-3,5-diphenyl-, bromide (298-93-1)
UNSPSC Code 12352207
NACRES NA.75

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)Health Hazard (GHS08)
GHS07,GHS08
Signal word  Warning
Hazard statements  H315-H319-H335-H341
Precautionary statements  P201-P202-P261-P302+P352-P305+P351+P338-P308+P313
target organs Respiratory system
PPE Eyeshields, Gloves, type N95 (US)
Hazard Codes  Xi,T,Xn
Risk Statements  46-68-36/37/38
Safety Statements  22-24/25-53-45-36/37-26
WGK Germany  3
RTECS  XF8060000
F  3-8-10
TSCA  TSCA listed
HS Code  29341000
Storage Class 11 - Combustible Solids
Hazard Classifications Eye Irrit. 2
Muta. 2
Skin Irrit. 2
STOT SE 3
Hazardous Substances Data 298-93-1(Hazardous Substances Data)
NFPA 704
1
2 1

Thiazolyl Blue price More Price(102)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 475989 MTT - CAS 298-93-1 - Calbiochem Membrane-permeable yellow dye that is reduced by mitochondrial reductases in living cells to form the dark blue product, MTT-formazan. 298-93-1 1g $118 2026-04-30 Buy
Sigma-Aldrich 475989 MTT - CAS 298-93-1 - Calbiochem Membrane-permeable yellow dye that is reduced by mitochondrial reductases in living cells to form the dark blue product, MTT-formazan. 298-93-1 10g $819 2026-04-30 Buy
TCI Chemical M3297 MTT [for Biochemical Research] 298-93-1 1G $64 2026-04-30 Buy
TCI Chemical D0801 3-(4,5-Dimethyl-2-thiazolyl)-2,5-diphenyltetrazolium Bromide >98.0%(T) 298-93-1 1g $96 2026-04-30 Buy
TCI Chemical D0801 3-(4,5-Dimethyl-2-thiazolyl)-2,5-diphenyltetrazolium Bromide >98.0%(T) 298-93-1 5g $288 2026-04-30 Buy
Product number Packaging Price Buy
475989 1g $118 Buy
475989 10g $819 Buy
M3297 1G $64 Buy
D0801 1g $96 Buy
D0801 5g $288 Buy

Thiazolyl Blue Chemical Properties, Uses, Production

Chemical Properties

Thiazolyl Blue Tetrazolium Blue (MTT) is a water soluble tetrazolium salt yielding a yellowish solution when prepared in media or salt solutions lacking phenol red. Dissolved MTT is converted to an insoluble purple formazan by cleavage of the tetrazolium ring by dehydrogenase enzymes. This water insoluble formazan can be solubilized using isopropanol or other solvents and the dissolved material is measured spectrophotometrically yielding absorbance as a function of concentration of converted dye.

Uses

Thiazolyl Blue Tetrazolium Blue (MTT) may be used in measurement of cell proliferation. MTT produces a yellowish solution that is converted to dark blue, water-insoluble MTT formazan by mitochondrial dehydrogenases of living cells. The blue crystals are solubilized with acidified isopropanol and the intensity is measured colorimetrically at 570 nm. MTT has been used as a histochemical/cytochemical reagent and for the detection of NAD. ADP-linked enzyme systems in tissue cannot be detected with MTT, due to binding of the cation by the cyanide trap used. MTT is rapidly reduced to the formazan, which chelates with nickel, copper, and cobalt; the cobalt chelate has been used in oxidative systems.

Definition

ChEBI: Thiazolyl Blue is the bromide salt of 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium. It has a role as a dye and a colorimetric reagent. It contains a 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium.

General Description

Thiazolyl Blue (MTT, Tetrazolium bromide, Methylthiazolyldiphenyl-tetrazolium bromide, Methylthialazole Tetrazolium) is a cell-permeable and positively charged colorimetric agent that is widely used to detect reductive metabolism in cells and to measure cell proliferation, cytotoxicity, and apoptosis. It is used as a direct indicator of cytotoxicity (such as for screening cancer drugs) and apoptosis. Thiazolyl Blue (MTT) is reduced from yellow color to purple formazan in living cells. As an electron acceptor, it is utilized for studying nicotinamide adenine dinucleotide phosphate (NADP)-dependent dehydrogenases.

Biochem/physiol Actions

Cell permeable: yes

storage

+4°C

Purification Methods

It is recrystallised by dissolving in MeOH containing a few drops of HBr and then adding dry Et2O to complete the crystallisation, wash the needles with Et2O and dry them in a vacuum desiccator over KOH. [Beyer & Pyl Chem Ber 87 1505 1954, Beilstein 27 III/IV 6045.]

Thiazolyl Blue Preparation Products And Raw materials

Raw materials

Preparation Products

Thiazolyl Blue Suppliers

Global Suppliers ( 615)
Supplier Tel Email Country ProdList Advantage
Hunan Hui Bai Yi New Materials Co., Ltd 0745-2866551 19976851779 3643281807@qq.com China 3389 58
Nanjing Sunlida Biological Technology Co., Ltd. 025-57798810 18652991625 sales@sunlidabio.com China 3223 55
Suzhou Haiheng Biological Pharmaceutical Co., Ltd. 0512-65045967 15365387483 sales@haihengpharm.com China 108 55
SuZhou Jonathan New Material Technology Co., Ltd. 0512-68312916,63926215 18912725070;18013709950 jon@jonnmt.com China 109 58
Hubei XinghengKang Chemical Technology Co., Ltd. 027-88878869 18162384755 xhkhu2014@163.com China 240 58
Hu' nan Yunbang Pharmaceutical Co., Ltd. 88532689 15386497078 yunbang@yunbangapi.com China 6935 58
Hunan Yongqi Chemical Co., LTD 0731-85561035 13319583233 yongqi@yongqichem.com China 681 58
Shanxi Nuocheng Biotechnology Co., Ltd 17835231871 572710841@qq.com China 7837 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
Supplier Advantage
Hunan Hui Bai Yi New Materials Co., Ltd 58
Nanjing Sunlida Biological Technology Co., Ltd. 55
Suzhou Haiheng Biological Pharmaceutical Co., Ltd. 55
SuZhou Jonathan New Material Technology Co., Ltd. 58
Hubei XinghengKang Chemical Technology Co., Ltd. 58
Hu' nan Yunbang Pharmaceutical Co., Ltd. 58
Hunan Yongqi Chemical Co., LTD 58
Shanxi Nuocheng Biotechnology Co., Ltd 58
J & K SCIENTIFIC LTD. 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 62

View Latest Price from Thiazolyl Blue manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Thiazolyl Blue pictures 2026-09-11 Thiazolyl Blue
298-93-1
 100G 98%min 30kg/month WUHAN FORTUNA CHEMICAL CO., LTD
Thiazolyl Blue pictures 2026-08-20 Thiazolyl Blue
298-93-1
 $30.00 98.73% 10g TargetMol Chemicals Inc.
3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2h-tetrazolium bromide pictures 2022-02-21 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2h-tetrazolium bromide
298-93-1
 1KG 99.3% 100 tons Honest Joy Holdings Limited

Thiazolyl Blue Spectrum

Thiazolyl Blue(298-93-1)MSThiazolyl Blue(298-93-1)1HNMRThiazolyl Blue(298-93-1)FT-IRThiazolyl Blue(298-93-1)IR

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2-(4,5-Dimethyl-2-thiazolyl)-3,5-diphenyl-2H-tetrazol-3-ium Bromide Thiazolyl Blue Tetrazolium Bromide Vetec(TM) reagent grade, 98% ACRYL/BIS 29:1 PREMIXED PWD ULTRA PURE 3-(4,5-Dimethyl-2-Thiazolyl)-2,5-Diphenyl 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyl-2,3-dihydro-1H-tetrazol-3-ium bromide 2-(4,5-Dimethylthiazol-2-yl)-3,5-diphenyl-2,3-dihydro-1H-tetrazol-3-ium bromide 2,5-diphenyl-3-(4,5-dimethylthiazol-2-yl)-2h-tetrazolium Bromide 2,5-diphenyl-3-(4,5-dimethylthiazol-2-yl)tetrazolium Bromide 2-(4,5-dimethylthiazol-2-yl)-3,5-diphenyl-2htetrazolium Bromide 3-(40 ,50-dimethyl-2-thiazolyl)-2,5-diphenyltetrazolium Bromide 3-(4,5-dimethylthiazolyl)-2,5-diphenyl-2h-tetrazolium Bromide 3-(4,5-dimethylthiazolyl)-2,5-diphenyltetrazolium Bromide Mtt Tetrazolium Nsc 60102 Thiazolyl Blue (sigma) METHYLTHIAZOLETETRAZOLIUM (MTT) METHYLTHIAZOLYLDIPHENYL-TETRAZOLIUM BROMIDE 3-(4,5-DIMETHYL-2-THIAZOL-2-YL)-2,5-DIPHENYL-2H-TETRAZOLIUM BROMIDE 3-(4,5-DIMETHYLTHIAZOL-2-YL)-2,5-DIPHYL-2 H-TETRAZOLIUM BROMIDE 3,[4,5-DIMETHYLTHIAZOL-2-YL]-2,5-DIPHENYLTETRAZOLIUM BROMIDE 3-(4,5-DIMETHYLTHIAZOL-2-YL)-2,5-DIPHENYL-2H-TETRAZOLIUM BROMIDE 3-(4,5-DIMETHYLITHIAZOLYL-2)-2,5-DIPHENYL MONOTETRAZOLIUM BROMIDE 3-(4,5-DIMETHYL-2-THIAZOLYL)-2,5-DIPHENYL-2H-TETRAZOLIUM BROMIDE 3-(4,5-DIMETHYLTHIAZOLYL-2)-2,5-DIPHENYL TETRAZOLIUM BROMIDE THIAZOYL BLUE TETRAZOLIUM BROMIDE THIAZOLYL BLUE THIAZOLE BLUE 2-(4,5-dimethyl-2-thiazolyl)-3,5-diphenyl-2h-tetrazoliubromide 2H-Tetrazolium,2-(4,5-dimethyl-2-thiazolyl)-3,5-diphenyl-,bromide Thiazolyl blue tetrazolium bromide, MTT THIAZOLYL BLUE extrapure AR Methylthiazolyldiphenyl-tetrazolium bromide, MTT, 3-(4,5-Dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide 2-(4,5-Dimethyl-1,3-thiazol-2-yl)-3,5-diphenyl-1,3,4-triaza-2-azoniacyclopenta-1,4-diene bromide 2-(4,5-Dimethyl-1,3-thiazol-2-yl)-3,5-diphenyltetrazol-2-ium bromide 2H-Tetrazolium, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-, bromide 2,5-Diphenyl-3-(4,5-dimethyl-2-thiazolyl)-2H-tetrazole-3-ium·bromide 2,5-Diphenyl-3-(4,5-dimethyl-2-thiazolyl)-3H-tetrazole-2-ium·bromide 2,5-Diphenyl-3-(4,5-dimethylthiazole-2-yl)-3H-tetrazole-2-ium·bromide MTT,98% 2H-TetrazoliuM,2-(4,5-diMethyl-2-thiazolyl)-3,5-diphenyl-, broMide (1:1) MTT (MTT) MTT)ThiazolylBlueTetrazoliuMB 3,[4,5-DIMETHYLTHIAZOL-2-YL]-2,5-DIPHENYLTETRAZOLIUM Nsc367079 Thiazolyl Blue Tetrazolium Bromide,3-(4,5-Dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide, MTT, Methylthiazolyldiphenyl-tetrazolium bromide Thiazolyl Blue Tetra 3-(4,5-DiMethyl-2-thiazolyl)-2,5-diphenyltetrazoliuM BroMide,MTT MTT (Thiazolyl blue) MTT - CAS 298-93-1 - Calbiochem Thiazolyl blue tetrazolium bromid (4,5-dimethythiazoyl-zyl2,5-diphenylterrajolium bromiole） 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-2h-tetrazoliubromide mmttetrazolium thiazolylbluemonotetrazolium 3-(4,5-Dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide~MTT~Thiazolyl Blue MTT (1.11714) MTT 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyl-2H-tetrazolium bromide MTT, 98% (3-(4,5-DIMETHYLTHIAZOL-2-YL)-2 , 5-DIPHENYL-2H-TETRAZOLIUM BROMIDE)