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ChemicalBook >> CAS DataBase List >>[1-(6-hydroxyhexyl)indol-3-yl]-naphthalen-1-ylmethanone

[1-(6-hydroxyhexyl)indol-3-yl]-naphthalen-1-ylmethanone

[1-(6-hydroxyhexyl)indol-3-yl]-naphthalen-1-ylmethanone Structure
[1-(6-hydroxyhexyl)indol-3-yl]-naphthalen-1-ylmethanone structure
CAS No.
1435934-29-4
Chemical Name:
[1-(6-hydroxyhexyl)indol-3-yl]-naphthalen-1-ylmethanone
Synonyms
JWH-019 6-Hydroxyhexyl;[1-(6-hydroxyhexyl)indol-3-yl]-naphthalen-1-ylmethanone;(1-(6-hydroxyhexyl)-1H-indol-3-yl)(naphthalen-1-yl)methanone;Methanone, [1-(6-hydroxyhexyl)-1H-indol-3-yl]-1-naphthalenyl-
CBNumber:
CB33879996
Molecular Formula:
C25H25NO2
Molecular Weight:
371.47
MDL Number:
MOL File:
1435934-29-4.mol
MSDS File:
SDS
Last updated:2023-05-15 10:43:11
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[1-(6-hydroxyhexyl)indol-3-yl]-naphthalen-1-ylmethanone Properties

Boiling point 593.1±30.0 °C(Predicted)
Density 1.13±0.1 g/cm3(Predicted)
solubility DMF: 30 mg/ml; DMF:PBS (pH 7.2) (1:4): 0.2 mg/ml; DMSO: 20 mg/ml; Ethanol: 5 mg/ml
form A crystalline solid
pka 15.19±0.10(Predicted)

[1-(6-hydroxyhexyl)indol-3-yl]-naphthalen-1-ylmethanone price More Price(16)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich S-043 JWH-019 6-Hydroxyhexyl metabolite solution 100?μg/mL in methanol, ampule of 1?mL, certified reference material, Cerilliant? 1435934-29-4 1ML $332 2026-04-30 Buy
Cayman Chemical 9000765 JWH 019 N-(6-hydroxyhexyl) metabolite ≥98% 1435934-29-4 1mg $129 2026-04-30 Buy
Cayman Chemical 9000765 JWH 019 N-(6-hydroxyhexyl) metabolite ≥98% 1435934-29-4 5mg $303 2026-04-30 Buy
Cayman Chemical 9000765 JWH 019 N-(6-hydroxyhexyl) metabolite ≥98% 1435934-29-4 10mg $469 2026-04-30 Buy
TRC TRC-J211475-25MG JWH-019 6-Hydroxyhexyl 1435934-29-4 25mg $230 2026-06-03 Buy
Product number Packaging Price Buy
S-043 1ML $332 Buy
9000765 1mg $129 Buy
9000765 5mg $303 Buy
9000765 10mg $469 Buy
TRC-J211475-25MG 25mg $230 Buy

[1-(6-hydroxyhexyl)indol-3-yl]-naphthalen-1-ylmethanone Chemical Properties,Uses,Production

Description

Cannabimimetic indoles, including certain JWH compounds, have been identified in herbal blends. JWH 018, a potent agonist of both the central cannabinoid (CB1) receptor and peripheral cannabinoid (CB2) receptor, has been found in many herbal blends and has been regulated in the United States and other countries. Studies indicate that JWH 018 is rapidly metabolized by the liver and that certain metabolites can be identified in the urine.1,2,3 JWH 019 is nearly identical to JWH 018 in structure and activity at both CB receptors.4 JWH 019 N-(6-hydroxyhexyl) metabolite is an expected metabolite of JWH 019, detectable both in serum and urine. Its biological activities have not been evaluated.

Uses

JWH-019 (Indole-d5) 6-Hydroxyhexyl is labelled JWH-019 6-Hydroxyhexyl (J211475), a urinary metabolite of JWH-019 (H296800) which acts as an N-1 alkyl indole cannabinoid receptor agonist.

References

1. Teske, J., Weller, J.P., Fieguth, A., et al. Sensitive and rapid quantification of the cannabinoid receptor agonist naphthalen-1-yl-(1-pentylindol-3-yl)methanone (JWH-018) in human serum by liquid chromatography-tandem mass spectrometry J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 878(27),2659-2663(2010).
2. Sobolevsky, T., Prasolov, I., and Rodchenkov, G. Detection of JWH-018 metabolites in smoking mixture post-administration urine Forensic Sci. Int. 200(1-3),141-147(2010).
3. Wintermeyer, A., Mller, I., Thevis, M., et al. In vitro phase I metabolism of the synthetic cannabimimetic JWH-018 Anal. Bioanal. Chem. 398(5),2141-2153(2010).
4. Aung, M.M., Griffin, G., Huffman, J.W., et al. Influence of the N-1 alkyl chain length of cannabimimetic indoles upon CB1 and CB2 receptor binding Drug Alcohol Depend. 60(2),133-140(2000).

[1-(6-hydroxyhexyl)indol-3-yl]-naphthalen-1-ylmethanone Preparation Products And Raw materials

Raw materials

Preparation Products

[1-(6-hydroxyhexyl)indol-3-yl]-naphthalen-1-ylmethanone Suppliers

Global( 9)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 400-920-5774 sales@glpbio.cn China 6705 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11123 58
Energy Chemical 021-58432009 400-005-6266 marketing@energy-chemical.com China 44871 58
LGC Science (Shanghai) Ltd. 17717235263 17717235263 offer.de@lgcgroup.com China 38135 58
Supplier Advantage
Shanghai Hongye Biotechnology Co. Ltd 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58
Energy Chemical 58
LGC Science (Shanghai) Ltd. 58

1435934-29-4([1-(6-hydroxyhexyl)indol-3-yl]-naphthalen-1-ylmethanone)Related Search:

JWH 019 N-(6-hydroxyhexyl) β-D-Glucuronide ADB-HEXINACA N-(6-hydroxyhexyl) metabolite MDA-19 N-(5-hydroxyhexyl) metabolite JWH 019 N-(5-hydroxyhexyl) metabolite-d5 JWH 019 N-(5-hydroxyhexyl) metabolite
[1-(6-hydroxyhexyl)indol-3-yl]-naphthalen-1-ylmethanone JWH-019 6-Hydroxyhexyl (1-(6-hydroxyhexyl)-1H-indol-3-yl)(naphthalen-1-yl)methanone Methanone, [1-(6-hydroxyhexyl)-1H-indol-3-yl]-1-naphthalenyl- 1435934-29-4