ChemicalBook >> CAS DataBase List >>N-[(2-Hydroxy-1-hydroxymethyl)ethyl]-11-oxo-9alpha,15s-dihydroxy-prosta-5z, 13e-dien-1-amide

N-[(2-Hydroxy-1-hydroxymethyl)ethyl]-11-oxo-9alpha,15s-dihydroxy-prosta-5z, 13e-dien-1-amide

N-[(2-Hydroxy-1-hydroxymethyl)ethyl]-11-oxo-9alpha,15s-dihydroxy-prosta-5z, 13e-dien-1-amide structure

CAS No.: 851761-42-7

Chemical Name:: N-[(2-Hydroxy-1-hydroxymethyl)ethyl]-11-oxo-9alpha,15s-dihydroxy-prosta-5z, 13e-dien-1-amide

Synonyms: PGD2-SA;PROSTAGLANDIN D2 SERINOL AMIDE;N-[(2-Hydroxy-1-hydroxymethyl)ethyl]-11-oxo-9alpha,15s-dihydroxy-prosta-5z, 13e-dien-1-amide;Prosta-5,13-dien-1-amide, 9,15-dihydroxy-N-[2-hydroxy-1-(hydroxymethyl)ethyl]-11-oxo-, (5Z,9α,13E,15S)- (9CI);(Z)-N-(1,3-dihydroxypropan-2-yl)-7-[(1R,2R,5S)-5-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-3-oxocyclopentyl]hept-5-enamide

CBNumber:: CB3398319

Molecular Formula:: C23H39NO6

Molecular Weight:: 425.56

MDL Number:: MFCD08062228

MOL File:: Mol file

MSDS File:: SDS

Last updated:2026-09-12 18:52:01

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N-[(2-Hydroxy-1-hydroxymethyl)ethyl]-11-oxo-9alpha,15s-dihydroxy-prosta-5z, 13e-dien-1-amide Properties

Boiling point	686.2±55.0 °C(Predicted)
Density	1.172±0.06 g/cm3(Predicted)
solubility	DMF: 25 mg/ml; DMSO: 25 mg/ml; Ethanol: 25 mg/ml; PBS (pH 7.2): 5 mg/ml
pka	13.86±0.60(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS02,GHS07,GHS08

Signal word

Danger

Hazard statements

H225-H319-H360

Precautionary statements

P201-P202-P210-P233-P240-P241-P242-P243-P264-P280-P303+P361+P353-P305+P351+P338-P308+P313-P337+P313-P370+P378-P403+P235-P405-P501

NFPA 704

	3
2		0

N-[(2-Hydroxy-1-hydroxymethyl)ethyl]-11-oxo-9alpha,15s-dihydroxy-prosta-5z, 13e-dien-1-amide price More Price(8)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Cayman Chemical	10192	Prostaglandin D2 serinol amide ≥95%	851761-42-7	100μg	$32	2026-04-30	Buy
Cayman Chemical	10192	Prostaglandin D2 serinol amide ≥95%	851761-42-7	500μg	$125	2026-04-30	Buy
Cayman Chemical	10192	Prostaglandin D2 serinol amide ≥95%	851761-42-7	1mg	$217	2026-04-30	Buy
Cayman Chemical	10192	Prostaglandin D2 serinol amide ≥98%	851761-42-7	5mg	$297	2021-12-16	Buy
ChemScene	CS-0139042	Prostaglandin D2 serinol amide	851761-42-7	1mg	$469	2026-06-04	Buy

Product number	Packaging	Price	Buy
10192	100μg	$32	Buy
10192	500μg	$125	Buy
10192	1mg	$217	Buy
10192	5mg	$297	Buy
CS-0139042	1mg	$469	Buy

N-[(2-Hydroxy-1-hydroxymethyl)ethyl]-11-oxo-9alpha,15s-dihydroxy-prosta-5z, 13e-dien-1-amide Chemical Properties, Uses, Production

Description

2-Arachidonyl glycerol (2-AG) exhibits cannabinoid (CB) agonist activity at the CB₁ receptor,¹ is an important endogenous monoglyceride species,² and is thus considered to be the natural ligand for the CB₁ receptor. 2-AG can also be sequentially metabolized by COX-2 and specific PG synthases to form PG 2-glyceryl esters.³ In activated RAW 264.7 cells, PGD₂ 2-glyceryl ester is the primary product of 2-AG metabolism in the COX pathway.³ PGD₂ serinol amide (PGD₂-SA) is a stable analog of PGD₂ 2-glyceryl ester. Unlike PGD₂ 2-glyceryl ester and other fatty acyl 2-glyceryl esters, PGD₂-SA will not isomerize to the less active primary (1-glyceryl) ester. The biological activity of PGD₂-SA has not yet been determined.

Uses

Prostaglandin D2 serinol amide is a weak inhibitor of the hydrolysis of [3H]2-oleoylglycerol[1].

Definition

ChEBI: PGD2-dihydroxypropanylamine is a prostanoid.

References

1. Sugiura, T., Kodaka, T., Kondo, S., et al. Is the cannabinoid CB₁ receptor a 2-arachidonoylglycerol receptor Structural requirements for triggering a Ca²⁺ transient in NG108-15 cells J. Biochem. 122(4),890-895(1997).
2. Kondo, S., Kondo, H., Nakane, S., et al. 2-Arachidonoylglycerol, an endogenous cannabinoid receptor agonist: Identification as one of the major species of monoacylglycerols in various rat tissues, and evidence for its generation through Ca²⁺-dependent and -independent mechanisms FEBS Lett. 429(2),152-156(1998).
3. Kozak, K.R., Crews, B.C., Morrow, J.D., et al. Metabolism of the endocannabinoids, 2-arachidonylgycerol and anandamide, into prostaglandin, thromboxane, and prostacyclin glycerol esters and ethanolamides J. Biol. Chem. 277(47),44877-44885(2002).

N-[(2-Hydroxy-1-hydroxymethyl)ethyl]-11-oxo-9alpha,15s-dihydroxy-prosta-5z, 13e-dien-1-amide Preparation Products And Raw materials

Raw materials

Preparation Products

N-[(2-Hydroxy-1-hydroxymethyl)ethyl]-11-oxo-9alpha,15s-dihydroxy-prosta-5z, 13e-dien-1-amide Suppliers

Global Suppliers ( 18)

Supplier	Tel	Email	Country	ProdList	Advantage
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9799	58
Shanghai Hongye Biotechnology Co. Ltd	400-9205774 400-920-5774	sales@glpbio.cn	China	6705	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11123	58
TargetMol Chemicals Inc.	15002134094	marketing@targetmol.cn	China	29874	58

Supplier	Advantage
Shanghai EFE Biological Technology Co., Ltd.	58
Shanghai Hongye Biotechnology Co. Ltd	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	58
TargetMol Chemicals Inc.	58

851761-42-7 (N-[(2-Hydroxy-1-hydroxymethyl)ethyl]-11-oxo-9alpha,15s-dihydroxy-prosta-5z, 13e-dien-1-amide) Related Search:

Prostaglandin E2 serinol amide (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxy-5-phenylpent-1-enyl]cyclopentyl]-N-(1,3-dihydroxypropan-2-yl)hept-5-enamide 15-deoxy-Δ12,14-Prostaglandin J2 serinol amide Prostaglandin F2α serinol amide (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]but-1-enyl]cyclopentyl]-N-(1,3-dihydroxypropan-2-yl)hept-5-enamide

Bimatoprost

1of2

(Z)-N-(1,3-dihydroxypropan-2-yl)-7-[(1R,2R,5S)-5-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-3-oxocyclopentyl]hept-5-enamide PROSTAGLANDIN D2 SERINOL AMIDE PGD2-SA Prosta-5,13-dien-1-amide, 9,15-dihydroxy-N-[2-hydroxy-1-(hydroxymethyl)ethyl]-11-oxo-, (5Z,9α,13E,15S)- (9CI) N-[(2-Hydroxy-1-hydroxymethyl)ethyl]-11-oxo-9alpha,15s-dihydroxy-prosta-5z, 13e-dien-1-amide 851761-42-7