N1-(3-Aminophenyl)acetamide
- CAS No.
- 102-28-3
- Chemical Name:
- N1-(3-Aminophenyl)acetamide
- Synonyms
- META AMINO ACETANILIDE;N-(3-AMINOPHENYL)ACETAMIDE;3-AMINOACETANILIDE;M-AMINOACETANILIDE;3'-Aminoacetanilide;FR-2203;AKOS BB-8162;WLN: ZR CMV1;3-AcetamidoaniL;ASISCHEM B52481
- CBNumber:
- CB3404737
- Molecular Formula:
- C8H10N2O
- Molecular Weight:
- 150.18
- MDL Number:
- MFCD00025229
- MOL File:
- 102-28-3.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 86-88 °C(lit.) |
|---|---|
| Boiling point | 271.72°C (rough estimate) |
| Density | 1.1392 (rough estimate) |
| refractive index | 1.6180 (estimate) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| form | powder to crystal |
| pka | 14.82±0.70(Predicted) |
| color | White to Gray to Brown |
| Water Solubility | 1-5 g/100 mL at 24 ºC |
| InChI | InChI=1S/C8H10N2O/c1-6(11)10-8-4-2-3-7(9)5-8/h2-5H,9H2,1H3,(H,10,11) |
| InChIKey | PEMGGJDINLGTON-UHFFFAOYSA-N |
| SMILES | C(NC1=CC=CC(N)=C1)(=O)C |
| CAS DataBase Reference | 102-28-3(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | Q5K7HYS7JJ |
| EPA Substance Registry System | 3'-Aminoacetanilide (102-28-3) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36-37/39 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | AD8050000 | |||||||||
| TSCA | TSCA listed | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29214200 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
|||||||||
| Toxicity | mouse,LD50,intravenous,320mg/kg (320mg/kg),U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#02899, | |||||||||
| REACH Registrations | Active | |||||||||
| NFPA 704 |
|
N1-(3-Aminophenyl)acetamide price More Price(45)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 485055 | 3′-Aminoacetanilide 97% | 102-28-3 | 250g | $163 | 2023-06-20 | Buy |
| TCI Chemical | A1533 | 3'-Aminoacetanilide >98.0%(HPLC)(T) | 102-28-3 | 25g | $17 | 2026-04-30 | Buy |
| Apolloscientific | OR30419 | 3'-Aminoacetanilide 98% | 102-28-3 | 25g | $21 | 2026-06-04 | Buy |
| Apolloscientific | OR30419 | 3'-Aminoacetanilide 98% | 102-28-3 | 100g | $24 | 2026-06-04 | Buy |
| AK Scientific | J50612 | 3'-Aminoacetanilide 95% | 102-28-3 | 5g | $12 | 2026-06-04 | Buy |
N1-(3-Aminophenyl)acetamide Chemical Properties,Uses,Production
Chemical Properties
light brown crystalline powder
Uses
3'-Aminoacetanilide is mainly used as reaction intermediates dyes and disperse dyes.
General Description
Gray solid.
Air & Water Reactions
Soluble in water.
Reactivity Profile
Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides.
Health Hazard
ACUTE/CHRONIC HAZARDS: When heated to decomposition N1-(3-Aminophenyl)acetamide emits toxic fumes.
Fire Hazard
Flash point data concerning N1-(3-Aminophenyl)acetamide are not available, however, N1-(3-Aminophenyl)acetamide is probably combustible.
Synthesis
122-28-1
102-28-3
m-Nitroacetanilide (1 g, 5.66 mmol) was dissolved in 100 mL of methanol and a catalytic amount of 10% palladium/activated charcoal (~0.015 g) was added. The reaction mixture was cooled via an ice bath and sodium borohydride (1 g, 26.43 mmol) was added in batches. Subsequently, the mixture was stirred vigorously for 1 hour. The reaction process was monitored by thin layer chromatography (TLC) using toluene-acetone (5:2, v/v) as unfolding agent. Upon completion of the reaction, the product was purified by silica gel column chromatography with toluene-acetone (5:2, v/v) as eluent. A white solid product was obtained in 75% yield with a melting point of 86-88 °C. Elemental analysis (C8H10N2O, Mr=150.18) Calculated values: C 63.98%, H 6.71%, N 18.65%; measured values: C 63.76%, H 6.50%, N 18.53%.1H NMR (400 MHz, DMSO-d6) δ: 9.58 (s, 1H, NH), 6.92 (t, 1H, H-2, J = 2.00 Hz), 6.88 (t, 1H, H-4, J = 8.00 Hz), 6.64 (dd, 1H, H-6, J1 = 0.80 Hz, J2 = 8.00 Hz), 6.23 (dd, 1H, H-5, J1 = 1.60 Hz, J2 = 8.00 Hz), 5.00 (bs, 2H, NH2), 1.99 (s, 3H , CH3-CO).13C NMR (100 MHz, DMSO-d6) δ: 167.85 (C=O), 148.85 (C1), 139.85 (C3), 128.75 (C4), 109.04 (C5), 106.93 (C6), 104.67 (C2), 23.98 (CH3-CO).
References
[1] Green Chemistry, 2018, vol. 20, # 1, p. 130 - 135
[2] Supramolecular Chemistry, 2010, vol. 22, # 10, p. 586 - 597
[3] Bioorganic Chemistry, 2014, vol. 57, p. 13 - 29
[4] Chemical & Pharmaceutical Bulletin, 1989, vol. 37, # 3, p. 615 - 617
[5] Journal of Chemical Research, 2006, # 4, p. 223 - 224
N1-(3-Aminophenyl)acetamide Preparation Products And Raw materials
Raw materials
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Preparation Products
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| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Taizhou zhenhe chemical co. LTD | 576-88887792 13386577269 | sales@zhenhechemical.com | China | 115 | 58 |
| Anhui Xuding Chemical Technology Co., Ltd | 15215638822 | 8938961@qq.com | China | 46 | 58 |
| Hangzhou Jingyou Chemical Co., Ltd. | 87211835 13957193240 | sales@jingyouchem.com | China | 211 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Beijing Ouhe Technology Co., Ltd | 13552068683 13522913783 | 2355560935@qq.com | China | 11777 | 60 |
| Accela ChemBio Co.,Ltd. | 021-50795510 4000665055 | marketing@accelachem.com | China | 10972 | 64 |
View Lastest Price from N1-(3-Aminophenyl)acetamide manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-20 | N1-(3-Aminophenyl)acetamide
102-28-3
|
$1.10 | 1g | 99.00% | 100 Tons Min | Dideu Industries Group Limited | |
 |
2026-05-28 | 3-Acetamidoaniline
102-28-3
|
$2.00-5.00 | 1KG | 99% | 10000kg | Hebei Chuanghai Biotechnology Co,.LTD | |
 |
2026-05-18 | N-(3-Aminophenyl)acetamide
102-28-3
|
1kg | 98% | Hefei Lbao Physical & Chemical Science Co.,Ltd |
-
- N1-(3-Aminophenyl)acetamide
102-28-3
- $1.10
- 99.00%
- Dideu Industries Group Limited
-
- 3-Acetamidoaniline
102-28-3
- $2.00-5.00
- 99%
- Hebei Chuanghai Biotechnology Co,.LTD
-
- N-(3-Aminophenyl)acetamide
102-28-3
- $0.00
- 98%
- Hefei Lbao Physical & Chemical Science Co.,Ltd
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