Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>R-(-)-Apomorphine

R-(-)-Apomorphine

R-(-)-Apomorphine Structure
R-(-)-Apomorphine structure
CAS No.
41372-20-7
Chemical Name:
R-(-)-Apomorphine
Synonyms
Apokyn;R-(-)-Apomorphine HCl Hemihydrate;R-(-)-APOMORPHINE HYDROCHLORIDE HEMIHYDRATE;r-(-)-apomorphine;Apokyn HeMihydrate;Ixense HeMihydrate;ApoMorphin HeMihydrate;ApoMorphine HeMihydrate;Apomorphine HCl hydrate;APOMORPHINEHCLHEMIHYDRATE
CBNumber:
CB3447114
Molecular Formula:
C17H20ClNO3
Molecular Weight:
321.8
MDL Number:
MFCD27966809
MOL File:
41372-20-7.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 06:32:05
Product description Number Pack Size Price
Apomorphine hydrochloride hemihydrate European Pharmacopoeia (EP) Reference Standard Y0001465 15 mg $241
Apomorphine hydrochloride PharmaceuticalSecondaryStandard;CertifiedReferenceMaterial PHR2621 500MG $263
R-(?)-Apomorphine hydrochloride hemihydrate calcined, ≥98.5% A4393 1g $319
Apomorphine hydrochloride United States Pharmacopeia (USP) Reference Standard 1041008 250mg $524
(R)-Apomorphine Hydrochloride Hemihydrate 166167 25mg $312
More product size
Request For Quotation

R-(-)-Apomorphine Properties

Melting point 285-287 °C(lit.)
alpha -48 º (c=1, H2O)
storage temp. Refrigerator
solubility H2O: ~10 mg/mL, clear, yellow-green
form Solid
color white to gray
PH pH(10g/l, 25℃) : 4.0～5.0
Water Solubility H2O: ~10mg/mL, clear, yellow-green
Merck 13,751
Stability Stable for 1 year from date of purchase as supplied. Solutions in distilled water may be stored at -20°C for up to 1 week.
InChI 1S/2C17H17NO2.2ClH.H2O/c2*1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12;;;/h2*2-6,13,19-20H,7-9H2,1H3;2*1H;1H2/t2*13-;;;/m11.../s1
InChIKey CXWQXGNFZLHLHQ-DPFCLETOSA-N
SMILES Cl[H].Cl[H].[H]O[H].[H][C@]12Cc3ccc(O)c(O)c3-c4cccc(CCN1C)c24.[H][C@]56Cc7ccc(O)c(O)c7-c8cccc(CCN5C)c68
CAS DataBase Reference 41372-20-7(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII F39049Y068
UNSPSC Code 41116107
NACRES NA.77

SAFETY

Risk and Safety Statements

Symbol(GHS)  Skull and Crossbones (GHS06)
GHS06
Signal word  Danger
Hazard statements  H301
Precautionary statements  P301+P330+P331+P310
PPE dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Hazard Codes  Xn
Risk Statements  22
Safety Statements  36
RIDADR  UN 2811 6.1/PG 3
WGK Germany  3
HS Code  2933997000
Storage Class 6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects
Hazard Classifications Acute Tox. 3 Oral

R-(-)-Apomorphine price More Price(31)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich Y0001465 Apomorphine hydrochloride hemihydrate European Pharmacopoeia (EP) Reference Standard 41372-20-7 15 mg $241 2026-04-30 Buy
Sigma-Aldrich PHR2621 Apomorphine hydrochloride PharmaceuticalSecondaryStandard;CertifiedReferenceMaterial 41372-20-7 500MG $263 2026-04-30 Buy
Sigma-Aldrich A4393 R-(?)-Apomorphine hydrochloride hemihydrate calcined, ≥98.5% 41372-20-7 1g $319 2026-04-30 Buy
Sigma-Aldrich 1041008 Apomorphine hydrochloride United States Pharmacopeia (USP) Reference Standard 41372-20-7 250mg $524 2026-04-30 Buy
Usbiological 166167 (R)-Apomorphine Hydrochloride Hemihydrate 41372-20-7 25mg $312 2026-06-03 Buy
Product number Packaging Price Buy
Y0001465 15 mg $241 Buy
PHR2621 500MG $263 Buy
A4393 1g $319 Buy
1041008 250mg $524 Buy
166167 25mg $312 Buy

R-(-)-Apomorphine Chemical Properties,Uses,Production

Description

Apomorphine (41372-20-7) is an archetypal dopamine pan-receptor agonist. Displays anti-Parkinsons activity in vivo.1 Protects against MPTP-induced neurotoxicity in a mouse mode1,2 In clinical use for Parkinson’s disease.4,5

Chemical Properties

Off-White Solid

Uses

emetic, antiparkinsonian, erextile dysfunction therapy

Uses

Dopamine (D1 and D2) receptor agonist. Emetic. Antiparkinsonian.

Uses

R-()-Apomorphine hydrochloride hemihydrate is a nonselective dopamine agonist with anti-Parkinsonian and neuroprotective effects in vivo.

brand name

Apokyn (Vernalis).

Purification Methods

Crystallise the salt from H2O (hemihydrate) and from EtOH. Crystals turn green on exposure to light. (see previous entry). NARCOTIC.

References

[1] Merck’s Index, Nachtrag 1930. Verlag von E. Merck, Darmstadt. 14 Seiten[J]. Archiv der Pharmazie, 1930, 268 6: 444-445. DOI:10.1002/ardp.19302680608
[2] MARK J MILLAN. Differential actions of antiparkinson agents at multiple classes of monoaminergic receptor. I. A multivariate analysis of the binding profiles of 14 drugs at 21 native and cloned human receptor subtypes.[J]. Journal of Pharmacology and Experimental Therapeutics, 2002, 303 2: 791-804. DOI:10.1124/jpet.102.039867
[3] EDNA GRÜNBLATT DSC (STUDENT). Apomorphine protects against MPTP-induced neurotoxicity in mice[J]. Movement Disorders, 2001, 14 4: 612-618. DOI:10.1002/1531-8257(199907)14:4<612::aid-mds1010>3.0.co;2-6
[4] MANON AUFFRET . Apomorphine pump in advanced Parkinson’s disease: Effects on motor and nonmotor symptoms with brain metabolism correlations[J]. Journal of the Neurological Sciences, 2017, 372: Pages 279-287. DOI:10.1016/j.jns.2016.11.080
[5] PETER JENNER  Regina K. Apomorphine - pharmacological properties and clinical trials in Parkinson’s disease[J]. Parkinsonism & related disorders, 2016, 33: Pages S13-S21. DOI:10.1016/j.parkreldis.2016.12.003

R-(-)-Apomorphine Preparation Products And Raw materials

Raw materials

MORPHINE Sodium sulfite CHLOROETHANE Activated carbon,decolor

Preparation Products

R-(-)-Apomorphine Suppliers

Global( 103)Suppliers
Supplier Tel Email Country ProdList Advantage
Henan Bao Enluo International TradeCo.，LTD 		+86-17331933971 deasea125996@gmail.com China 2451 58
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21531 55
CONIER CHEM AND PHARMA LIMITED 		sales@conier.com China 49906 58
TargetMol Chemicals Inc. 		+1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
Shaanxi Dideu Medichem Co. Ltd 		+86-29-81139210 +86-17392587031 1059@dideu.com China 9984 58
Hebei Dangtong Import and export Co LTD 		+86-86-4001020630 +86-13910575315 admin@hbdangtong.com China 996 58
Aladdin Scientific 		tp@aladdinsci.com United States 54746 58
Mainchem Co., Ltd. +86-0592-6210733 sale@mainchem.com China 32288 55
LGM Pharma 1-(800)-881-8210 inquiries@lgmpharma.com United States 2110 70
Spectrum Chemical Manufacturing Corp. 021-021-021-67601398-809-809-809 15221380277 marketing_china@spectrumchemical.com China 9643 60
Supplier Advantage
Henan Bao Enluo International TradeCo.，LTD 		58
Henan Tianfu Chemical Co.,Ltd. 		55
CONIER CHEM AND PHARMA LIMITED 		58
TargetMol Chemicals Inc. 		58
Shaanxi Dideu Medichem Co. Ltd 		58
Hebei Dangtong Import and export Co LTD 		58
Aladdin Scientific 		58
Mainchem Co., Ltd. 55
LGM Pharma 70
Spectrum Chemical Manufacturing Corp. 60

View Lastest Price from R-(-)-Apomorphine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
R-(-)-Apomorphine pictures 2026-07-01 R-(-)-Apomorphine
41372-20-7
 $11460.00-11500.00 10kilograms 99% 100tons Hebei Dangtong Import and export Co LTD
R-(-)-Apomorphine pictures 2023-06-30 R-(-)-Apomorphine
41372-20-7
 $10.00 1kg 99.99% 50000tons Henan Bao Enluo International TradeCo.，LTD
  • R-(-)-Apomorphine pictures
  • R-(-)-Apomorphine
    41372-20-7
  • $11460.00-11500.00
  • 99%
  • Hebei Dangtong Import and export Co LTD

R-(-)-Apomorphine Spectrum

R-(-)-Apomorphine(41372-20-7)1HNMRR-(-)-Apomorphine(41372-20-7)RamanR-(-)-Apomorphine(41372-20-7)IR

41372-20-7(R-(-)-Apomorphine)Related Search:

Quinhydrone Methyl acetate 8-Hydroxyquinoline Ethoxyquin Methyl acrylate
Bensulfuron methyl Kresoxim-methyl Quinoline Yellow Quinclorac Methylparaben
2-METHYL-1,3-PROPANEDIOL Isoquinoline Poly(tetrahydrofuran) Thiophanate-methyl Methyl
MORPHINE apomorphine Parathion-methyl

1of4

(r)-5,6,6a,7-tetrahydro-6-methyl-4h-dibenzo[de,g]quinoline-10,11-diol Apomorphine hydrochloride R-(-)- (6Ar)-5,6,6A,7-tetrahydro-6-methyl-4H-dibenzo(de,G)chinolin-10,11-diol hydrochlorid 6a-beta-aporphine-10,11-diol APOMORPHINE HYDROCHLORIDE, HEMIHYDRATE 4H-Dibenzode,gquinoline-10,11-diol, 5,6,6a,7-tetrahydro-6-methyl-, hydrochloride, hydrate (2:1), (6aR)- APOMORPHINEHCLHEMIHYDRATE APOMORPHINEHYDROCHLORIDE,HEMIHYDRATE,USP Apomophine hydrochloride R-(-)-Apomorphine hemihydrate hydrochloride 4H-Dibenzo(de,G)quinoline-10,11-diol, 5,6,6A,7-tetrahydro-6-methyl-, hydrochloride, hemihydrate, (R)- Apokyn Apomorphin hydrochlorid wasser (2/1) Apomorphine Hydrochloride (250 mg) (-)-10,11-Dihydroxy-aporphine Hydrochloride HeMihydrate (6aR)-5,6,6a,7-Tetrahydro-6-Methyl-4H-dibenzo[de,g]quinoline-10,11-diol Hydrochloride HeMihydrate 6aβ-Aporphine-10,11-diol Hydrochloride HeMihydrate Apokyn HeMihydrate ApoMorphin HeMihydrate ApoMorphine HeMihydrate Ixense HeMihydrate l-ApoMorphine HeMihydrate r-(-)-apomorphine:6a-beta-aporphine-10,11-diol: (r)-5,6,6a,7-tetrahydro-6-methyl-4h-dibenzo(de,g)QUINOLINE-10,11-diol R-(-)-APOMORPHINE HYDROCHLORIDE HEMIHYDRATE r-(-)-apomorphine Apomorphine hydrochloride hemihydrate CRS Apomorphine HCl hydrate R-(-)-Apomorphine USP/EP/BP Apomorphine Hydrochloride (1041008) a . N-(2-a mi noe th yl)-2-(b e nzylph e nyla mi no)a c e ta mi d e . Apomorphine HCl Reference Standard Apomorphine hydrochloride hemihydrate in methanol Apomorphine HCl, dopamine agonist R-(?)-Apomorphine hydrochloride hemihydrate Apomorphine hydrochloride hemihydrate (R-(-)-Apomorphine hydrochloride hemihydrate) Apomorphine Hydrochloride Hemihydrate 1.0 mg/ml in Methanol (as anhydrous free base) R-(-)-Apomorphine HCl Hemihydrate 41372-20-7 C17H18ClNO212H2O C17H17NO2HCl12H2O C17H17NO222HClH2O C17H20ClNO3 C17H18ClNO2H2O 31279 Nonselective dopamine agonist; causes nausea and emesis. Chiral Building Blocks Asymmetric Synthesis Others Heterocyclic Building Blocks Inhibitors APOKYN Chiral Reagents Heterocycles Intermediates & Fine Chemicals Pharmaceuticals Agonists Dopaminergics Neurotransmitters