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2-Methyl-1,3-propanediol

2-Methyl-1,3-propanediol structure

CAS No.: 2163-42-0

Chemical Name:: 2-Methyl-1,3-propanediol

Synonyms: METHYLPROPANEDIOL;2-methylpropane-1,3-diol;MP Diol;2-Methyl-1,3-propanediol (MPO);MPDIOL(R);MPDIOL MPD;2-METHYL-1,3-;MP diol glycol;MPDIOL(R) GLYCOL;β-Hydroxyisobutanol

CBNumber:: CB3313835

Molecular Formula:: C4H10O2

Molecular Weight:: 90.12

MDL Number:: MFCD00082586

MOL File:: 2163-42-0.mol

MSDS File:: SDS

Last updated:2026-09-12 18:51:59

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2-Methyl-1,3-propanediol Properties

Melting point	-91 °C (lit.)
Boiling point	123-125 °C/20 mmHg (lit.)
Density	1.015 g/mL at 25 °C (lit.)
vapor density	3.2 (vs air)
refractive index	n20/D 1.445(lit.)
Flash point	>230 °F
storage temp.	Sealed in dry,Room Temperature
solubility	Chloroform (Soluble), DMSO (Slightly), Methanol (Slightly)
pka	14.51±0.10(Predicted)
form	Oil
color	Colourless
Odor	little to no odor
BRN	1731422
Henry's Law Constant	6.9×10² mol/(m³Pa) at 25℃, Wang et al. (2017)
Cosmetics Ingredients Functions	SOLVENT
Cosmetic Ingredient Review (CIR)	2-METHYL-1,3-PROPANEDIOL (2163-42-0)
InChI	1S/C4H10O2/c1-4(2-5)3-6/h4-6H,2-3H2,1H3
InChIKey	QWGRWMMWNDWRQN-UHFFFAOYSA-N
SMILES	CC(CO)CO
LogP	-0.740 (est)
CAS DataBase Reference	2163-42-0(CAS DataBase Reference)
EWG's Food Scores	1
FDA UNII	N8F53B3R4R
NIST Chemistry Reference	Propane-1,3-diol, 2-methyl-(2163-42-0)
EPA Substance Registry System	1,3-Propanediol, 2-methyl- (2163-42-0)
UNSPSC Code	12162002
NACRES	NA.23

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H319-H315-H335

Precautionary statements

P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362

PPE

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Risk Statements

36/37/38

Safety Statements

26-36/37/39

WGK Germany

TSCA

TSCA listed

HS Code

2905.39.9000

Storage Class

10 - Combustible liquids

Hazardous Substances Data

2163-42-0(Hazardous Substances Data)

REACH Registrations

Active

NFPA 704

	1
0		0

2-Methyl-1,3-propanediol price More Price(37)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	375721	2-Methyl-1,3-propanediol 99%	2163-42-0	1l	$52.5	2026-04-30	Buy
Sigma-Aldrich	375721	2-Methyl-1,3-propanediol 99%	2163-42-0	3l	$134	2026-04-30	Buy
TCI Chemical	M1114	2-Methyl-1,3-propanediol >98.0%(GC)	2163-42-0	25mL	$22	2026-04-30	Buy
TCI Chemical	M1114	2-Methyl-1,3-propanediol >98.0%(GC)	2163-42-0	500mL	$39	2026-04-30	Buy
TRC	TRC-H943635-50G	2-Methyl-1,3-propandiol (b-Hydroxyisobutanol)	2163-42-0	50g	$103	2026-06-03	Buy

Product number	Packaging	Price	Buy
375721	1l	$52.5	Buy
375721	3l	$134	Buy
M1114	25mL	$22	Buy
M1114	500mL	$39	Buy
TRC-H943635-50G	50g	$103	Buy

2-Methyl-1,3-propanediol Chemical Properties,Uses,Production

Description

2-Methyl-1,3-propanediol, MPD, is produced by Arco with an estimated capacity of about 7000 t/a. The process is designed for the production of 1,4-butanediol as an alternative to Reppe technology and the acetoxylation of butadiene. The raw material propylene oxide is isomerized to allyl alcohol in the fifirst step. Hydroformylation of allyl alcohol gives 4- hydroxybutanal (79 %) and 3-hydroxy-2-methylpropanal (11 %). The last step comprises hydrogenation of the n and iso intermediates to the corresponding diols.

Uses

β-Hydroxyisobutanol is used as a reagent in the synthesis of pyrazolo[1,5-a]pyridinecarbonyl-substituted spirocyclic piperidine ketals as inhibitors of HCV protein NS4B and of hepatitis C viral replication and their lack of cytotoxicity in human cells.

Application

2-Methyl-1,3-propanediol (MDP), with its branched and irregular structure, affords noncrystalline resins. It is used in polyesters for solvent- and waterborne coatings, imparting them lower viscosity than neopentyl glycol, easy processability, good flexibility, weatherability, and toughness. 2-Methyl-1,3-propanediol is used in paints with low content of volatile organic compounds (VOC) as two-component polyurethane coating and coil coating. It is also used in glass-fiber-reinforced unsaturated polyesters and gel coats. MPD is used for chemical modification of polyethylene terephthalate (PET) used in production of fibers and films. Low content of MPD in PET fibers improves the dye uptake and in films it improves clarity, toughness, elongation, and shrinkage. Plasticizers, elastomers, adhesives, cosmetics, and personal care products are other uses of MPD.

Synthesis

Equivalents of asymmetrized 2-methyl-1,3-propanediol are prepared by elaborating compounds obtained in optically active form via non-enzymatic asymmetric synthesis[1].

References

[1]Banfi, L., & Guanti, G. (1993). Asymmetrized 2-Methyl-1,3-propanediol and Its Equivalents: Preparation and Synthetic Applications. Synthesis, 1993(11), 1029–1056. https://doi.org/10.1055/s-1993-25991

2-Methyl-1,3-propanediol Preparation Products And Raw materials

Raw materials

1,3-Propanediol, 2-methyl-, 1,3-diacetate 1,3-Propanediol, 2-methylene-, 1-acetate Dimethyl 3-methylglutarate 2-methylenepropane-1,3-diyl diacetate ACETOXYACETONE

2-Methylene-1,3-propanediol Diethyl ethoxymethylenemalonate

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Preparation Products

ZENIPLATIN 1,4-Butanediol 1,3-Dioxane, 5-methyl-2-(2-methylpropyl)-, cis- Carbonic acid 2-methyl-1,3-propanediyl ester 3-methyloxetane

2-Methyl-1,3-propanediol Suppliers

Global( 396)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Jiangsu Runfeng Synthetic Technology Co., Ltd.	0513-66017678 18551497631	507167383@qq.com	China	4995	58
Jinan Hui Feng Da chemical Co., LTD.	13156148719 15554103218;13156148719;15550483828	jnhuifengda@163.com	China	983	58
Nantong Fotunte Biotechnology Co., Ltd.	0513-86920019 13382489788	2084708089@qq.com	China	500	58
JINAN SJIJITONGDA CHEMICAL CO.,LTD	15153132128 15153132128	sjtd6688@163.com	China	355	58
Tianjin Zhongxin Chemtech Co., Ltd.	022-66880623	sales@tjzxchem.com	China	612	60
J & K SCIENTIFIC LTD.	18210857532 18210857532	jkinfo@jkchemical.com	China	96815	76
TCI (Shanghai) Development Co., Ltd.	021-67121386	Sales-CN@TCIchemicals.com	China	24512	81
Energy Chemical	400-0056266	sales8178@energy-chemical.com	China	44850	61
Beijing Ouhe Technology Co., Ltd	13552068683 13522913783	2355560935@qq.com	China	11777	60
JinYan Chemicals(ShangHai) Co.,Ltd.	13817811078	sales@jingyan-chemical.com	China	9963	60

Supplier	Advantage
Jiangsu Runfeng Synthetic Technology Co., Ltd.	58
Jinan Hui Feng Da chemical Co., LTD.	58
Nantong Fotunte Biotechnology Co., Ltd.	58
JINAN SJIJITONGDA CHEMICAL CO.,LTD	58
Tianjin Zhongxin Chemtech Co., Ltd.	60
J & K SCIENTIFIC LTD.	76
TCI (Shanghai) Development Co., Ltd.	81
Energy Chemical	61
Beijing Ouhe Technology Co., Ltd	60
JinYan Chemicals(ShangHai) Co.,Ltd.	60

2-Methyl-1,3-propanediol: Branched Aliphatic Diol
2-Methyl-1,3-propanediol is a water-soluble, low-volatility branched diol with two terminal hydroxyl groups, widely used to sy....
Jun 29,2026

View Lastest Price from 2-Methyl-1,3-propanediol manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-09-13	2-METHYL-1,3-PROPANEDIOL 2163-42-0			0.99		RongNa Biotechnology Co.,Ltd
2026-09-11	2-METHYL-1,3-PROPANEDIOL 2163-42-0	$800.00-1000.00	1kg	99%	5000	HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
2026-09-02	2-methyl-1,3-propanediol 2163-42-0		20kg	99%	20 tons	Qingdao RENAS Polymer Material Co., Ltd.

2-METHYL-1,3-PROPANEDIOL
2163-42-0
0.99
RongNa Biotechnology Co.,Ltd

2-METHYL-1,3-PROPANEDIOL
2163-42-0
$800.00-1000.00
99%
HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD

2-methyl-1,3-propanediol
2163-42-0
$0.00
99%
Qingdao RENAS Polymer Material Co., Ltd.

2-Methyl-1,3-propanediol Spectrum

2-METHYL-1,3-PROPANEDIOL(2163-42-0)MS 2-METHYL-1,3-PROPANEDIOL(2163-42-0)¹HNMR 2-METHYL-1,3-PROPANEDIOL(2163-42-0)¹³CNMR 2-METHYL-1,3-PROPANEDIOL(2163-42-0)IR1 2-METHYL-1,3-PROPANEDIOL(2163-42-0)Raman

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2-Methyl-1,3-propanediol (MPO) Methyl propane diol (MP Diol) 2-Methyl-1,3-propanediol 99% 1,3-DIHYDROXY-2-METHYLPROPANE 2-METHYL-PROPAN-1,3-DIOL 2-methyl-3-propanediol 3-Propanediol,2-methyl-1 MP diol glycol MPDIOL(R) MPDIOL(R) GLYCOL 3-Methyl-1,3-Propanediol 1,3-Propanediol, 2-methyl- 2-METHYL-1,3-PROPANEDIOL 98+% MPDIOL MPD 2-Methyl-1,3-propandiol (β-Hydroxyisobutanol) 2-Methyl-1,3-propanediol> 2-METHYL-1,3-PROPANEDIOL ISO 9001：2015 REACH β-Hydroxyisobutanol methylpropylene glycol 2-Methyl-1,3-propandiol (b-Hydroxyisobutanol) 2-METHYL-1,3- Methyl propylene glycol(MPO) 2-methylpropane-1,3-diol METHYLPROPANEDIOL MP Diol 2-Methyl-1,3-propanediol 2163-42-0 CH3CHCH2OH2 application fields are synthetic leather pulp, polyurethane coating, food flexible packaging composite with polyurethane adhesive and so on. Alcohols Monomers Polymer Science