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5'-Aminoimidazole-4-carboxamide-1-beta-D-ribofuranosyl 5'-monophosphate

5'-Aminoimidazole-4-carboxamide-1-beta-D-ribofuranosyl 5'-monophosphate structure

CAS No.: 3031-94-5

Chemical Name:: 5'-Aminoimidazole-4-carboxamide-1-beta-D-ribofuranosyl 5'-monophosphate

Synonyms: ZMP;5-AMINOIMIDAZOLE-4-CARBOXAMIDE-1-BETA-D-RIBOFURANOSYL 5'-MONOPHOSPHATE;acadesine 5'-monophosphate;AICA-Riboside, 5′-Phosphate;NSC 283955;NSC 292227;AICAR-5'-MP;Acaribonucleotide;AICAR-5'-MP / ZMP;AICAR-5′,-MP

CBNumber:: CB3466890

Molecular Formula:: C9H15N4O8P

Molecular Weight:: 338.21

MDL Number:: MFCD00057264

MOL File:: 3031-94-5.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-09-12 18:52:03

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5'-Aminoimidazole-4-carboxamide-1-beta-D-ribofuranosyl 5'-monophosphate Properties

Melting point	198-202°C dec.
Boiling point	845.3±75.0 °C(Predicted)
Density	2.30±0.1 g/cm3(Predicted)
storage temp.	-20°C
solubility	DMSO (Slightly, Heated, Sonicated), Methanol (Slightly), Water (Slightly)
form	White to light pink solid
pka	1.86±0.10(Predicted)
color	White to Pink
optical activity	[α]/D -69.0±3.0°, c = 0.1 in sodium bicarbonate
Water Solubility	water: 1mg/mL DMSO: 30mg/mL
Stability	Hygroscopic
InChI	1S/C9H15N4O8P/c10-7-4(8(11)16)12-2-13(7)9-6(15)5(14)3(21-9)1-20-22(17,18)19/h2-3,5-6,9,14-15H,1,10H2,(H2,11,16)(H2,17,18,19)/t3-,5-,6-,9-/m1/s1
InChIKey	UDYDDOATBNVEES-UUOKFMHZSA-N
SMILES	O[C@H]1[C@@H](O)[C@H](N2C=NC(C(N)=O)=C2N)O[C@@H]1COP(O)(O)=O
FDA UNII	F0X88YW0YK
UNSPSC Code	41116107
NACRES	NA.77

SAFETY

Risk and Safety Statements

PPE	Eyeshields, Gloves, type N95 (US)
Safety Statements	24/25
WGK Germany	3
HS Code	29349990
Storage Class	11 - Combustible Solids

5'-Aminoimidazole-4-carboxamide-1-beta-D-ribofuranosyl 5'-monophosphate price More Price(29)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	A1393	5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranosyl 5′-monophosphate ≥93%	3031-94-5	50mg	$769	2026-04-30	Buy
Sigma-Aldrich	123041	AICA-Riboside, 5?-Phosphate	3031-94-5	25mg	$292	2026-04-30	Buy
Sigma-Aldrich	06595	5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranosyl 5′-monophosphate analytical standard	3031-94-5	25mg	$795	2026-04-30	Buy
Cayman Chemical	33907	AICA Ribonucleotide ≥95%	3031-94-5	1mg	$36	2026-04-30	Buy
Cayman Chemical	33907	AICA Ribonucleotide ≥95%	3031-94-5	5mg	$128	2026-04-30	Buy

Product number	Packaging	Price	Buy
A1393	50mg	$769	Buy
123041	25mg	$292	Buy
06595	25mg	$795	Buy
33907	1mg	$36	Buy
33907	5mg	$128	Buy

5'-Aminoimidazole-4-carboxamide-1-beta-D-ribofuranosyl 5'-monophosphate Chemical Properties, Uses, Production

Chemical Properties

White Powder With Pink Tinge.

Uses

AICAR monophosphate is a 5′′-phosphorylated analog of cell permeable AICAR that mimics AMP. AICAR is an adenosine monophophate (AMP)-activated protein kinase (AMPK) activator/agonist.

Definition

ChEBI: AICA ribonucleotide is a 1-(phosphoribosyl)imidazolecarboxamide that is acadesine in which the hydroxy group at the 5' position has been converted to its monophosphate derivative. It has a role as a cardiovascular drug, a plant metabolite, a human metabolite, an Escherichia coli metabolite, a Saccharomyces cerevisiae metabolite and a mouse metabolite. It is a 1-(phosphoribosyl)imidazolecarboxamide and an aminoimidazole. It is functionally related to an acadesine. It is a conjugate acid of a 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide(2-).

General Description

5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranosyl 5′-monophosphate (AICAR monophosphate) is an intermediate metabolite in the purine de novo synthesis pathway and a potent activator of the human AMP-activated protein kinase (AMPK) activity in vitro. It can play an important regulatory role.

Biochem/physiol Actions

A 5′-phosphorylated analog of cell permeable AICAR that mimics adenosine monophosphate (AMP). It is an AMP-activated protein kinase (AMPK) activator.In humans, 5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranosyl 5′-monophosphate (AICAR) is found to be accumulated in numerous metabolic diseases. It can increase the endurance of sedentary mice. AICAR exhibits antiproliferative effects. It can induce apoptosis of aneuploid cells.

5'-Aminoimidazole-4-carboxamide-1-beta-D-ribofuranosyl 5'-monophosphate Preparation Products And Raw materials

Raw materials

Preparation Products

5'-Aminoimidazole-4-carboxamide-1-beta-D-ribofuranosyl 5'-monophosphate Suppliers

Global Suppliers ( 96)

Supplier	Tel	Email	Country	ProdList	Advantage
J & K SCIENTIFIC LTD.	18210857532 18210857532	jkinfo@jkchemical.com	China	96815	76
3B Pharmachem (Wuhan) International Co.,Ltd.	18930552037	3bsc@sina.com	China	15813	69
Chemsky（shanghai）International Co.,Ltd.	021-50135380	shchemsky@sina.com	China	32273	50
S.Z. PhyStandard Bio-Tech. Co., Ltd.	0755-83725681-603		China	4484	50
Sigma-Aldrich	021-61415566 800-8193336	orderCN@merckgroup.com	China	51389	80
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9799	58
Shanghai YuanYe Biotechnology Co., Ltd.	15026964105	2881489226@qq.com	China	89667	60
Shanghai Jizhi Biochemical Technology Co. Ltd.	021-4009004166/18616739031 18616739031	3007523370@qq.com	China	40000	58
ROSEWA HOLDING GROUP CO.,LIMITED	+86-023-62871537	sales@rosewachem.com	China	2812	58
TargetMol Chemicals Inc.	+1-781-999-5354; +1-00000000000	marketing@targetmol.com	United States	32431	58

Supplier	Advantage
J & K SCIENTIFIC LTD.	76
3B Pharmachem (Wuhan) International Co.,Ltd.	69
Chemsky（shanghai）International Co.,Ltd.	50
S.Z. PhyStandard Bio-Tech. Co., Ltd.	50
Sigma-Aldrich	80
Shanghai EFE Biological Technology Co., Ltd.	58
Shanghai YuanYe Biotechnology Co., Ltd.	60
Shanghai Jizhi Biochemical Technology Co. Ltd.	58
ROSEWA HOLDING GROUP CO.,LIMITED	58
TargetMol Chemicals Inc.	58

View Latest Price from 5'-Aminoimidazole-4-carboxamide-1-beta-D-ribofuranosyl 5'-monophosphate manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-07-15	AICAR monophosphate 3031-94-5	$85.00-303.00		99.80%	10g	TargetMol Chemicals Inc.
2025-08-22	AICAR 3031-94-5		1g	99% min	20 tons	Dingwang Technology (Wuhan) Co., Ltd.
2025-04-04	5'-AMINOIMIDAZOLE-4-CARBOXAMIDE-1-BETA-D-RIBOFURANOSYL 5'-MONOPHOSPHATE 3031-94-5		1KG	98%	1Ton	Henan Aochuang Chemical Co.,Ltd.

AICAR monophosphate
3031-94-5
$85.00-303.00
99.80%
TargetMol Chemicals Inc.

AICAR
3031-94-5
$0.00
99% min
Dingwang Technology (Wuhan) Co., Ltd.

5'-AMINOIMIDAZOLE-4-CARBOXAMIDE-1-BETA-D-RIBOFURANOSYL 5'-MONOPHOSPHATE
3031-94-5
98%
Henan Aochuang Chemical Co.,Ltd.

5'-Aminoimidazole-4-carboxamide-1-beta-D-ribofuranosyl 5'-monophosphate Spectrum

5'-AMINOIMIDAZOLE-4-CARBOXAMIDE-1-BETA-D-RIBOFURANOSYL 5'-MONOPHOSPHATE(3031-94-5)¹HNMR

3031-94-5 (5'-Aminoimidazole-4-carboxamide-1-beta-D-ribofuranosyl 5'-monophosphate) Related Search:

AICAR 5-Amino-4-imidazolecarboxamide 3-Ethyl-3H-imidazole-4-carbaldehyde 5'-Aminoimidazole-4-carboxamide-1-beta-D-ribofuranosyl 5'-monophosphate 4-(1,3-dithiolan-2-yl)-N-(3-hydroxypyridin-2-yl)benzamide

Adenosine, N-(3-hydroxyphenyl)-, 2',3',5'-triacetate

1of2

AICAR monophosphate, ZMP, N1-(β-D-5μ-Phosphoribofuranosyl)-5-aminoimidazole-4-carboxamide 1-(5-O-Phosphono-β-D-ribofuranosyl)-5-amino-1H-imidazole-4-carboxamide 5-Amino-1-(5-O-phosphono-β-D-ribofuranosyl)-1H-imidazole-4-carboxamide 5-Amino-4-imidazolecarboxamide ribonucleotide 5'-Phosphoribosyl-4-carboxamide-5-aminoimidazole 5-Aino-1-(5-O-phosphono-beta-D-ribofuranosyl)-1H-imidazole-4-carboxamide 5-Aminomidazole-4-carboxamide-1-β-D-ribofuranosyl 5-Monophosphate Acaribonucleotide 5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranosyl 5'-monophosphate ,98% 5-Aminoimidazole-4-carboxamide-1-b-D-ribofuranose 5'-monophosphate ((2R,3S,4R,5R)-5-(5-aMino-4-carbaMoyl-1H-iMidazol-1-yl)-3,4-dihydroxytetrahydrofuran-2-yl)Methyl dihydrogen phosphate N1-(β-D-5′-Phosphoribofuranosyl)-5-aminoimidazole-4-carboxamide NSC 283955 NSC 292227 AICA-Riboside, 5′-Phosphate AICAR MONOPHOSPHATE AICAR MONOPHOSPHATE, N1-[BETA-D-5'-PHOSPHORIBOFURANOSYL]-5-AMINOIMIDAZOLE-4-CARBOXAMIDE 5-Aminoimidazole-4-Carboxamide-1-b-D-Ribofuranosyl 5Monophosphate 5-aminoimidazole-4-carboxamide-1-β-d-ribofuranosyl 5'-monophosphate [(2R,3R,4R,5R)-5-(5-amino-4-carbamoyl-imidazol-1-yl)-3,4-dihydroxy-oxolan-2-yl]methoxyphosphonic acid aicaribonucleotide 5-amino-1-(5-O-phosphono-beta-D-ribofuranosyl)-1H-imidazole-4-carboxamide AICAR-5'-MP / ZMP 5'-AMINOIMIDAZOLE-4-CARBOXAMIDE-1-BETA-D-RIBOFURANOSYL 1H-Imidazole-4-carboxamide, 5-amino-1-(5-O-phosphono-β-D-ribofuranosyl)- 5-Aminoimidazole-4-carboxamide-1-β-D-Ribofuranosyl 5’-Monophosphate Aminoimidazole Carboxamide Ribonucleoside 5'-AMINOIMIDAZOLE-4-CARBOXAMIDE-1-BETA-D-RIBOFURANOSYL 5'-MONOPHOSPHATE USP/EP/BP 1H-Imidazole-4-carboxamide,5-amino-1-(5-O-phosphono-b-D-ribofuranosyl)- acadesine 5'-monophosphate AICAR-5'-MP 5-aminoimidazole-4-carboxamide ribonucleotide 1H-?Imidazole-?4-?carboxamide,5-?amino-?1-?(5-?O-?phosphono-?β-?D-?ribofuranosyl)?- AICA-Ribotide (NSC 283955) AICAR monophosphate, 10 mM in DMSO 5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranosyl 5′-monophosphate 5'-Aminoimidazole-4-carboxamide-1-β-D-ribofuranosyl AICAR-5′,-MP AICA-Riboside, 5'-Phosphate,BR 5-AMINOIMIDAZOLE-4-CARBOXAMIDE-1-BETA-D-RIBOFURANOSYL 5'-MONOPHOSPHATE ZMP 5'-Aminoimidazole-4-carboxamide-1-beta-D-ribofuranosyl 5'-monophosphate 3031-94-5 C9H15N4O8P BioChemical Metabolomics Metabolic Pathways Metabolites and Cofactors on the Metabolic Pathways Chart Nucleotide Bases & Related Reagents Carbohydrates & Derivatives Nucleotides