Deltazinone
- CAS No.
- 894554-89-3
- Chemical Name:
- Deltazinone
- Synonyms
- Deltazinone;Deltazinone 1 (Deltazinone1);6H-Pyrazolo[3,4-d]pyridazine-6-butanamide, 2,7-dihydro-3,4-dimethyl-2-(4-methylphenyl)-7-oxo-N-(2-phenylpropyl)-
- CBNumber:
- CB34844700
- Molecular Formula:
- C27H31N5O2
- Molecular Weight:
- 457.57
- MDL Number:
- MOL File:
- 894554-89-3.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| Deltazinone 1 98.79% | CS-0028646 | 5mg | $704 |
| Deltazinone 1 98.79% | CS-0028646 | 10mg | $1137 |
| Deltazinone 1 98.79% | CS-0028646 | 25mg | $2058 |
| Deltazinone 1 98.79% | CS-0028646 | 50mg | $3250 |
| Deltazinone 1 98.79% | CS-0028646 | 5mg | $704 |
Deltazinone price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0028646 | Deltazinone 1 98.79% | 894554-89-3 | 5mg | $704 | 2026-06-04 | Buy |
| ChemScene | CS-0028646 | Deltazinone 1 98.79% | 894554-89-3 | 10mg | $1137 | 2026-06-04 | Buy |
| ChemScene | CS-0028646 | Deltazinone 1 98.79% | 894554-89-3 | 25mg | $2058 | 2026-06-04 | Buy |
| ChemScene | CS-0028646 | Deltazinone 1 98.79% | 894554-89-3 | 50mg | $3250 | 2026-06-04 | Buy |
| ChemScene | CS-0028646 | Deltazinone 1 98.79% | 894554-89-3 | 5mg | $704 | 2026-06-04 | Buy |
Deltazinone Chemical Properties,Uses,Production
Description
Deltazinone is highly potent and selective PDEδ inhibitor. Deltazinone exhibits less unspecific cytotoxicity than the previously reported Deltarasin and demonstrates a high correlation with the phenotypic effect of PDEδ knockdown in a set of human pancreatic cancer cell lines.
Uses
Deltazinone 1, a pyrazolopyridazinone, is a highly selective PDEδ inhibitor with a KD of 8nM. Deltazinone 1 inhibits the PDEδ-Ras interaction. Deltazinone 1 shows a dose-dependent inhibitory response on proliferation in oncogenic KRas-dependent cell lines[1][2].
IC 50
PDEδ: 8 nM (Kd)
References
[1] Bjrn Papke, et al. Identification of pyrazolopyridazinones as PDEδ inhibitors. Nat Commun. 2016 Apr 20;7:11360. DOI:10.1038/ncomms11360
[2] Pablo Martín-Gago, et al. Structure-based development of PDEδ inhibitors. Biol Chem. 2017 May 1;398(5-6):535-545. DOI:10.1515/hsz-2016-0272
Deltazinone Preparation Products And Raw materials
Raw materials
Preparation Products
Deltazinone Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32466 | 58 |
| TargetMol Chemicals Inc. | +17819995354 | marketing@targetmol.com | United States | 19956 | 58 |
| Shanghai Beckham Medical Technology Co., Ltd | 13816613772 | huahero21@sina.com | China | 2826 | 55 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29868 | 58 |
| Nanjing Shizhou Biology Technology Co.,Ltd | 025-85560043 15850508050 | cindy.huang@synzest.com | China | 12000 | 58 |
View Lastest Price from Deltazinone manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-05-11 | Deltazinone
894554-89-3
|
$1520.00-2500.00 | 10g | TargetMol Chemicals Inc. |
-
- Deltazinone
894554-89-3
- $1520.00-2500.00
- TargetMol Chemicals Inc.
