(2-pyridyldithio)-PEG4-propargyl
- CAS No.
- 2170240-99-8
- Chemical Name:
- (2-pyridyldithio)-PEG4-propargyl
- Synonyms
- (2-pyridyldithio)-PEG4-propargyl;Pyridine, 2-(3,6,9,12-tetraoxapentadec-14-yn-1-yldithio)-
- CBNumber:
- CB34849381
- Molecular Formula:
- C16H23NO4S2
- Molecular Weight:
- 357.49
- MDL Number:
- MFCD31580154
- MOL File:
- 2170240-99-8.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501 |
(2-pyridyldithio)-PEG4-propargyl price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0115167 | (2-Pyridyldithio)-PEG4-propargyl ≥97% | 2170240-99-8 | 100mg | $240 | 2026-06-04 | Buy |
| ChemScene | CS-0115167 | (2-Pyridyldithio)-PEG4-propargyl ≥97% | 2170240-99-8 | 250mg | $380 | 2026-06-04 | Buy |
| BroadPharm | bp-23858 | (2-pyridyldithio)-PEG4-propargyl 98% | 2170240-99-8 | 100MG | $320 | 2026-05-24 | Buy |
| BroadPharm | bp-23858 | (2-pyridyldithio)-PEG4-propargyl 98% | 2170240-99-8 | 250MG | $540 | 2026-05-24 | Buy |
| aablocks | AA019EEK | (2-pyridyldithio)-PEG4-propargyl 97% | 2170240-99-8 | 100mg | $204 | 2026-05-29 | Buy |
(2-pyridyldithio)-PEG4-propargyl Chemical Properties, Uses, Production
Description
(2-pyridyldithio)-PEG4-propargyl is a PEG linker which contains a pyridyl disulfide moiety and a propargyl group. The pyridyl disulfide group can react with thiol groups of proteins over a wide range of pH levels. The propargyl group can react with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage. The hydrophilic PEG linker increases the water solubility of compounds in aqueous media.
Uses
(2-Pyridyldithio)-PEG4-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
(2-pyridyldithio)-PEG4-propargyl Preparation Products And Raw materials
Raw materials
Preparation Products
(2-pyridyldithio)-PEG4-propargyl Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Xi'an Confluore Biological Technology Co., Ltd. | +86-156-80926068 +86-15680926068 | 1924344760@qq.com | China | 4229 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Henan Weituxi Chemical Technology Co., Ltd. | 0371-63284658 18135795563 | 3905209149@qq.com | China | 9705 | 58 |
| Shanghai Haohong Pharmaceutical Co., Ltd. | 400-8210725 4008210725 | malulu@leyan.com | China | 54996 | 58 |
| Hangzhou Taorui Biotechnology Co., Ltd | QQ1259737804 15268198094 | sales@torreybio.com | China | 4129 | 58 |
| Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd | 0431-80514535 19917294565 | et@chemextension.com | China | 5061 | 58 |
| TargetMol Chemicals Inc. | 4008200310 15002144251 | marketing@tsbiochem.com | China | 24951 | 58 |
| Beijing Solarbio Science & Tecnology Co., Ltd. | 010-50973130 17801761073 | Gsiyu@solarbio.com | China | 50460 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11963 | 58 |
| Jilin Chinese Academy of Sciences-yanshen Technology | 18143011203 | ET-market@chemextension.com | China | 38923 | 58 |
View Latest Price from (2-pyridyldithio)-PEG4-propargyl manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-15 | (2-Pyridyldithio)-PEG4-propargyl
2170240-99-8
|
$30.00 | 10g | TargetMol Chemicals Inc. | |||
 |
2025-06-07 | (2-pyridyldithio)-PEG4-propargyl
2170240-99-8
|
50mg | >99.00% | 50mg | Xian confluore Biological Technology Co., Ltd. |
-
- (2-Pyridyldithio)-PEG4-propargyl
2170240-99-8
- $30.00
- TargetMol Chemicals Inc.
-
- (2-pyridyldithio)-PEG4-propargyl
2170240-99-8
- $0.00
- >99.00%
- Xian confluore Biological Technology Co., Ltd.
