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E3 Ligase Ligand-Linker Conjugates 58

CAS No.
2172820-14-1
Chemical Name:
E3 Ligase Ligand-Linker Conjugates 58
Synonyms
VH032-PEG5-COOH;VH 032 amide-PEG5-acid;(S,R,S)-AHPC-PEG5-COOH;VHL Ligand-Linker Conjugates 16;E3 Ligase Ligand-Linker Conjugates 58;L-Prolinamide, N-(18-carboxy-1-oxo-4,7,10,13,16-pentaoxaoctadec-1-yl)-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)-;(S)-21-((2S,4R)-4-Hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidine-1-carbonyl)-22,22-dimethyl-19-oxo-4,7,10,13,16-pentaoxa-20-azatricosan-1-oic acid;1-{[(2S)-1-[(2S,4R)-4-hydroxy-2-({[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl}carbamoyl)pyrrolidin-1-yl]-3,3-dimethyl-1-oxobutan-2-yl]carbamoyl}-3,6,9,12,15-pentaoxaoctadecan-18-oic acid
CBNumber:
CB36127045
Molecular Formula:
C36H54N4O11S
Molecular Weight:
750.9
MDL Number:
MFCD32693900
MOL File:
2172820-14-1.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 03:48:42

E3 Ligase Ligand-Linker Conjugates 58 Properties

storage temp. -20°C, stored under nitrogen
solubility DMSO: ≥ 100 mg/mL (133.17 mM)
form Solid
color Colorless to off-white

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

E3 Ligase Ligand-Linker Conjugates 58 price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0106354 (S,R,S)-AHPC-PEG5-COOH ≥98% 2172820-14-1 25mg $190 2026-06-04 Buy
ChemScene CS-0106354 (S,R,S)-AHPC-PEG5-COOH ≥98% 2172820-14-1 50mg $320 2026-06-04 Buy
ChemScene CS-0106354 (S,R,S)-AHPC-PEG5-COOH ≥98% 2172820-14-1 100mg $550 2026-06-04 Buy
BroadPharm bp-44813 (S,R,S)-AHPC-PEG5-COOH 2172820-14-1 100MG $210 2026-05-24 Buy
BroadPharm bp-44813 (S,R,S)-AHPC-PEG5-COOH 2172820-14-1 250MG $430 2026-05-24 Buy
Product number Packaging Price Buy
CS-0106354 25mg $190 Buy
CS-0106354 50mg $320 Buy
CS-0106354 100mg $550 Buy
bp-44813 100MG $210 Buy
bp-44813 250MG $430 Buy

E3 Ligase Ligand-Linker Conjugates 58 Chemical Properties, Uses, Production

Uses

(S,R,S)-AHPC-PEG5-COOH (VH032-PEG5-COOH) is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 5-unit PEG linker used in PROTAC technology[1].

Biological Activity

(S,R,S)-AHPC-PEG5-COOH (VH032-PEG5-COOH) is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 5-unit PEG linker used in PROTAC technology[1].

IC 50

VHL

storage

Store at -20°C

References

[1]. Chi JJ, et al. A novel strategy to block mitotic progression for targeted therapy. EBioMedicine. 2019 Oct 25. pii: S2352-3964(19)30677-2.

E3 Ligase Ligand-Linker Conjugates 58 Preparation Products And Raw materials

Raw materials

Preparation Products

E3 Ligase Ligand-Linker Conjugates 58 Suppliers

Global Suppliers ( 23)
Supplier Tel Email Country ProdList Advantage
Sichuan Wei Keqi Biological Technology Co., Ltd. 028-81700200 18116577057 3003855609@qq.com China 7717 56
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 400-920-5774 sales@glpbio.cn China 6705 58
Beijing Minruida Technology Co., Ltd. 010-82387566 sales@mreda.com.cn China 19323 58
Jilin Province Woda Biotechnology Co., Ltd. 13504435624 1927928688@qq.com China 1644 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
Shanghai Kaiwei Chemical Technology Co., Ltd. 021-58461859 15821823057 service@aiviche.com China 49299 58
Shanghai Haohong Pharmaceutical Co., Ltd. 400-8210725 4008210725 malulu@leyan.com China 54996 58
Bide Pharmatech Ltd. 400-1647117 13681763483 product02@bidepharm.com China 59929 58
TargetMol Chemicals Inc. 4008200310 15002144251 marketing@tsbiochem.com China 24951 58

View Latest Price from E3 Ligase Ligand-Linker Conjugates 58 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
(S,R,S)-AHPC-PEG5-COOH pictures 2025-08-22 (S,R,S)-AHPC-PEG5-COOH
2172820-14-1
$46.00 10g TargetMol Chemicals Inc.
E3 Ligase Ligand-Linker Conjugates 58 (S,R,S)-AHPC-PEG5-COOH VH032-PEG5-COOH VHL Ligand-Linker Conjugates 16 L-Prolinamide, N-(18-carboxy-1-oxo-4,7,10,13,16-pentaoxaoctadec-1-yl)-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)- VH 032 amide-PEG5-acid (S)-21-((2S,4R)-4-Hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidine-1-carbonyl)-22,22-dimethyl-19-oxo-4,7,10,13,16-pentaoxa-20-azatricosan-1-oic acid 1-{[(2S)-1-[(2S,4R)-4-hydroxy-2-({[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl}carbamoyl)pyrrolidin-1-yl]-3,3-dimethyl-1-oxobutan-2-yl]carbamoyl}-3,6,9,12,15-pentaoxaoctadecan-18-oic acid 2172820-14-1 C36H54N4O11S