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BISNORCHOLENALDEHYDE

BISNORCHOLENALDEHYDE Structure
BISNORCHOLENALDEHYDE structure
CAS No.
3986-89-8
Chemical Name:
BISNORCHOLENALDEHYDE
Synonyms
BNKY018-PG01;Bisnorcholeldehyde;KETOBISNORALDEHYDE;Bisnorcholenaldehyde;Progesterone Impurity 7;Progesterone Impurity 24;Progesterone EP Impurity I;Didroprogesterone impurity 2;Progesterone EP Impurity I-02;(20S)-20-Formylpregn-4-en-3-one
CBNumber:
CB3670455
Molecular Formula:
C22H32O2
Molecular Weight:
328.49
MDL Number:
MFCD00056488
MOL File:
Mol file
MSDS File:
SDS
Last updated:2026-05-28 04:11:30
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BISNORCHOLENALDEHYDE Properties

Melting point 159-160 °C
Boiling point 459.4±14.0 °C(Predicted)
Density 1.07±0.1 g/cm3(Predicted)
solubility Chloroform (Slightly), Dichloromethane (Slightly), Methanol (Slightly)
form Solid
color White to Off-White
InChI InChI=1S/C22H32O2/c1-14(13-23)18-6-7-19-17-5-4-15-12-16(24)8-10-21(15,2)20(17)9-11-22(18,19)3/h12-14,17-20H,4-11H2,1-3H3/t14-,17+,18-,19+,20+,21+,22-/m1/s1
InChIKey XVPJEGGIGJLDQK-HOFZUOGSSA-N
SMILES C1(=O)C=C2[C@](C)(CC1)[C@]1([H])[C@]([H])([C@@]3([H])[C@@](CC1)(C)[C@@H]([C@@H](C=O)C)CC3)CC2

SAFETY

Risk and Safety Statements

Symbol(GHS)  Health Hazard (GHS08)
GHS08
Signal word  Danger
Hazard statements  H351-H362-H360
Precautionary statements  P201-P202-P281-P308+P313-P405-P501-P201-P260-P263-P264-P270-P308+P313
REACH Registrations Active

BISNORCHOLENALDEHYDE price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC TRC-B508830-25MG Bisnorcholenaldehyde 3986-89-8 25mg $276 2026-06-03 Buy
TRC TRC-B508830-250MG Bisnorcholenaldehyde 3986-89-8 250mg $2016 2026-06-03 Buy
aablocks AA0076SX (20S)-3-Oxopregn-4-ene-20-carboxaldehyde 3986-89-8 25mg $341 2026-05-28 Buy
aablocks AA0076SX (20S)-3-Oxopregn-4-ene-20-carboxaldehyde 3986-89-8 250mg $1733 2026-05-28 Buy
J&W Pharmlab 99R0035 Bisnorcholenaldehyde 99% 3986-89-8 250mg $150 2026-05-21 Buy
Product number Packaging Price Buy
TRC-B508830-25MG 25mg $276 Buy
TRC-B508830-250MG 250mg $2016 Buy
AA0076SX 25mg $341 Buy
AA0076SX 250mg $1733 Buy
99R0035 250mg $150 Buy

BISNORCHOLENALDEHYDE Chemical Properties, Uses, Production

Description

Androstenedione is the main product after phytosterol fermentation by Mycobacteria. Bisnorcholenaldehyde (BA; 3-Oxopregn-4-ene-20-carboxaldehyde) is one of the by-products produced during fermentation. Bisnorcholenaldehyde is an essential intermediate in the production of progesterone, which is used to treat threatened abortion or habitual abortion disease caused by luteal insufficiency. It is a precursor of androgen, estrogen, glucocorticoid and intermediates of steroid hormone synthesis[1]. In addition, BA is used in magnetic-based graphene composites with steroidal diamine dimer as a potential drug in hyperthermia cancer therapy.

Uses

Bisnorcholenaldehyde is hydrocarbon derivatives and can be used as reference materials for medical impurities.

Toxics Screening Level

The initial threshold screening level (ITSL) for progesterone 4 is 0.04 μg/m3 based on an annual averaging time.

References

[1] Shi-Dong Xu. “Refining androstenedione and bisnorcholenaldehyde from mother liquor of phytosterol fermentation using macroporous resin column chromatography followed by crystallization.” Journal of Chromatography B 1079 (2018): Pages 9-14.

BISNORCHOLENALDEHYDE synthesis

40736-33-2
3986-89-8
Synthesis of BISNORCHOLENALDEHYDE from 3-keto-23,24-bisnorchol-4-en-22-ol

BISNORCHOLENALDEHYDE Preparation Products And Raw materials

Raw materials

Preparation Products

21-hydroxy-20-methylpregn-4-en-3-one

BISNORCHOLENALDEHYDE Suppliers

Global Suppliers ( 39)
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Daicel Chiral Technologies (China)CO.,LTD 021-50460086-9 15921403865 han_yajun@dctc.daicel.com China 7909 65
Quality Control Solutions Ltd. 0755-66853366 13670046396 orders@qcsrm.com China 18188 56
Shandong Boluoda Biological Technology Co., Ltd. 0531-68651502 2310993908@qq.com China 3157 58
Shanghai Kewel Chemical Co., Ltd. 021-64609169 18901607656 greensnown@163.com China 9883 50
Shijiazhuang yaoBo Pharmaceutical Co., Ltd. 15633056635 2880679888@qq.com China 2759 58
Hubei Yangxin Medical Technology Co., Ltd. 15374522761 3003392093@yongstandards.com China 9995 55
Shenzhen Polymeri Biochemical Technology Co., Ltd. +86-400-002-6226 sales@rrkchem.com China 57336 58
Shenzhen Botel Biotechnology Co. Ltd. 13316949107 13316968096 1979313431@qq.com China 9619 58
TOSUN PHARM 020-66392521-118 18922260391 3004261881@qq.com China 7994 58
Supplier Advantage
J & K SCIENTIFIC LTD. 76
Daicel Chiral Technologies (China)CO.,LTD 65
Quality Control Solutions Ltd. 56
Shandong Boluoda Biological Technology Co., Ltd. 58
Shanghai Kewel Chemical Co., Ltd. 50
Shijiazhuang yaoBo Pharmaceutical Co., Ltd. 58
Hubei Yangxin Medical Technology Co., Ltd. 55
Shenzhen Polymeri Biochemical Technology Co., Ltd. 58
Shenzhen Botel Biotechnology Co. Ltd. 58
TOSUN PHARM 58

BISNORCHOLENALDEHYDE Spectrum

BISNORCHOLENALDEHYDE(3986-89-8)MSBISNORCHOLENALDEHYDE(3986-89-8)1HNMRBISNORCHOLENALDEHYDE(3986-89-8)13CNMR

3986-89-8 (BISNORCHOLENALDEHYDE) Related Search:

20α-Acetoxy-4-pregnen-3-one (17α)-Pregn-4-ene-3,20-dione 4,9(11)-Pregnadien-3,20-dione 4-Pregnen-20-beta-ol-3-one 4-Pregnen-20-alpha-ol-3-one
Progesterone EP Impurity F Progesterone EP Impurity G 1,4-Pregnadien-3,20-dione Benzene, 2-[[2-[(6-broMohexyl)oxy]ethoxy]Methyl]-1,3-dichloro 21ξ-morpholino-23,24-dinor-chola-4,20-dien-3-one
Androstenone hydrazone 17-Iodoandrosta-5,16-dien-3beta-ol tert-Butyl (2-(2,2-dimethyl-4H-benzo[d][1,3]dioxin-6-yl)-2-oxoethyl)carbamate CarbaMic acid, [(2R)-2-(2,2-diMethyl-4H-1,3-benzodioxin-6-yl)-2-hydroxyethyl]-, 1,1-diMethylethyl ester 2-Oxazolidinone, 5-(2,2-diMethyl-4H-1,3-benzodioxin-6-yl)-, (5R)-
N-(1-Cyclohexen-1-yl)morpholine Abiraterone Pregna-4,6-diene-3,20-dione

1of4

KETOBISNORALDEHYDE 3-KETO-4-PREGNENE-20-BETA-CARBOXALDEHYDE 4-PREGNEN-20BETA-CARBOXALDEHYDE-3-ONE 4-PREGNEN-3-ONE-20-BETA-CARBOXALDEHYDE Progesterone EP Impurity I Progesterone Impurity 7 Progesterone EP Impurity I (S-isomer) (20S)-3-oxopregn-4-ene-20-carboxaldehyde BNKY018-PG01 Bisnorcholeldehyde Pregn-4-ene-20-carboxaldehyde, 3-oxo-, (20S)- (S)-2-((8S,9S,10R,13S,14S,17R)-10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)propanal 3-Oxo-pregn-4-ene-20α- carboxaldehyde Progesterone Impurity 24 (20S)-20-Formylpregn-4-en-3-one (S)-2-((8S,9S,10R,13S,14S,17R)-10,13-Dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)propanal (Progesterone Impurity) Bisnorcholenaldehyde Progesterone EP Impurity I-02 Progesterone Impurity(S-Isomer) Didroprogesterone impurity 2 (2S)-2-[(8S,9S,10R,13S,14S,17R)-10,13-dimethyl-3-oxo-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl]propanal (2S)-2-[(8S,9S,10R,13R,14S,17R)-10,13-dimethyl-3-oxo-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl]propanal 3986-89-8