DEPMPO
- CAS No.
- 157230-67-6
- Chemical Name:
- DEPMPO
- Synonyms
- DEPMPO;DEPMPO, Spin trap;5-(Diethoxyphosphoryl)-;5-(DIETHYLPHOSPHONO)-5-METHYL-1-PYRROLINE N-OXIDE;5-(DIETHOXYPHOSPHORYL)-5-METHYL-1-PYRROLINE-N-OXIDE;5-(DIETHOXYPHOSPHONYL)-5-METHYL-1-PYRROLINE-N-OXIDE;5-(Diethylphosphono)-5-methyl-1-pyrrolineN-Oxide>5-(Diethylphosphono)-5-methyl-1-pyrroline N-Oxide;2-DIETHYLPHOSPHONO-2-METHYL-3,4-DIHYDRO-2H-PYRROLE 1-OXIDE;(2-METHYL-3,4-DIHYDRO-1-OXIDE-2H-PYRROL-2-YL)DIETHYLPHOSPHONATE
- CBNumber:
- CB3675728
- Molecular Formula:
- C9H18NO4P
- Molecular Weight:
- 235.22
- MDL Number:
- MFCD01074976
- MOL File:
- 157230-67-6.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS05 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H335-H318-H315 | |||||||||
| Precautionary statements | P280-P305+P351+P338-P310-P264-P280-P302+P352-P321-P332+P313-P362 | |||||||||
| NFPA 704 |
|
DEPMPO price More Price(30)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 10006435 | DEPMPO ≥98% | 157230-67-6 | 50mg | $134 | 2026-04-30 | Buy |
| Cayman Chemical | 10006435 | DEPMPO ≥98% | 157230-67-6 | 250mg | $565 | 2026-04-30 | Buy |
| Cayman Chemical | 10006435 | DEPMPO ≥98% | 157230-67-6 | 500mg | $1058 | 2026-04-30 | Buy |
| Usbiological | 272129 | 5-(Diethoxyphosphoryl)-5-methyl-1-pyrroline-N-oxide | 157230-67-6 | 5mg | $403 | 2026-06-03 | Buy |
| Usbiological | 272129 | 5-(Diethoxyphosphoryl)-5-methyl-1-pyrroline-N-oxide | 157230-67-6 | 10mg | $602 | 2026-06-03 | Buy |
DEPMPO Chemical Properties, Uses, Production
Description
DEPMPO (157230-67-6) is a spin trap capable of detecting oxygen, nitrogen, sulfur and carbon-centered free radicals both in vitro and in vivo. DEPMPO is useful for distinguishing between superoxide-dependent pathways of hydroxyl radical generation, and those that are superoxide independent.
Chemical Properties
DEPMPO is Pale Yellow Oil
Uses
DEPMPO is the most efficient spin trap for the in vitro detection of O-, N-, S- and C-centered free radicals both invitro and invivo. It has a longer life-time than DMPO and can distinguish between superoxide-dependent and independent mechanisms that lead to the hydroxyl radical. It is less lipophilic (Kp=0.16) than DIPPMPO.
Uses
DEPMPO is a spin trap useful as a probe for free radical formation during myocardial ischemia/reperfusion injury. An analogue of DMPO
References
[1] KE JIAN LIU . Evaluation of DEPMPO as a spin trapping agent in biological systems[J]. Free Radical Biology and Medicine, 1999, 26 5: Pages 714-721. DOI:10.1016/s0891-5849(98)00251-2
[2] HONGLIAN SHI . Evaluation of spin trapping agents and trapping conditions for detection of cell-generated reactive oxygen species[J]. Archives of biochemistry and biophysics, 2005, 437 1: Pages 59-68. DOI:10.1016/j.abb.2005.02.028
[3] MARCEL CULCASI . EPR spin trapping evaluation of ROS production in human fibroblasts exposed to cerium oxide nanoparticles: Evidence for NADPH oxidase and mitochondrial stimulation[J]. Chemico-Biological Interactions, 2012, 199 3: Pages 161-176. DOI:10.1016/j.cbi.2012.08.007
[4] FRANCESCO TAMPIERI*. Comment on “Water-Soluble Fluorescent Probe with Dual Mitochondria/Lysosome Targetability for Selective Superoxide Detection in Live Cells and in Zebrafish Embryos”[J]. ACS Sensors, 2019, 4 11: 3080-3083. DOI:10.1021/acssensors.9b01358
DEPMPO Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hangzhou Sulfuchem Material Technology Co., Ltd. | 0571-86113725 15372021306 | sales@sulfuchem.com | China | 969 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15813 | 69 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32273 | 50 |
| Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. | 025-66113011 13913916777 | cfzhang@aikonchem.com | China | 19902 | 55 |
| 9ding chemical ( Shanghai) Limited | 4009209199 | sales@9dingchem.com | China | 22497 | 55 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9799 | 58 |
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