Quinoline-6-carboxylic acid ethyl ester
- CAS No.
- 73987-38-9
- Chemical Name:
- Quinoline-6-carboxylic acid ethyl ester
- Synonyms
- Nsc 85328;Brn 0148800;Ethyl 6-quinolinecarboxylate;ethyl quinoline-6-carboxylate;6-quinolinecarboxylicacid,ethylester;Quinoline-6-carboxylic acid ethyl ester;4-22-00-01197 (Beilstein Handbook Reference);QUINOLINE-6-CARBOXYLIC ACID ETHYL ESTER ISO 9001：2015 REACH
- CBNumber:
- CB3677904
- Molecular Formula:
- C12H11NO2
- Molecular Weight:
- 201.22
- MDL Number:
- MFCD00047612
- MOL File:
- 73987-38-9.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| storage temp. | Sealed in dry,Room Temperature |
|---|---|
| Appearance | Off-white to pink Solid |
| FDA UNII | TVD8MFO8DJ |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
Quinoline-6-carboxylic acid ethyl ester price More Price(42)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Chem-Impex | 24715 | Ethyl 6-quinolinecarboxylate ≥95%(HPLC) | 73987-38-9 | 250MG | $81.92 | 2026-05-19 | Buy |
| Chem-Impex | 24715 | Ethyl 6-quinolinecarboxylate ≥95%(HPLC) | 73987-38-9 | 1G | $159.24 | 2026-05-19 | Buy |
| Chem-Impex | 24715 | Ethyl 6-quinolinecarboxylate ≥95%(HPLC) | 73987-38-9 | 5G | $610.11 | 2026-05-19 | Buy |
| Matrix Scientific | 074634 | Ethyl quinoline-6-carboxylate | 73987-38-9 | 1.00g | $231 | 2026-05-18 | Buy |
| Matrix Scientific | 074634 | Ethyl quinoline-6-carboxylate | 73987-38-9 | 5.00g | $798 | 2026-05-18 | Buy |
Quinoline-6-carboxylic acid ethyl ester Chemical Properties, Uses, Production
Synthesis
10349-57-2
64-17-5
73987-38-9
1. 6-Quinolinecarboxylic acid (9.50 g, 54.9 mmol) was dissolved in ethanol (250 ml), concentrated sulfuric acid (2 ml) was added and the reaction was carried out at reflux for 8 hours. After completion of the reaction, the solvent was removed by evaporation. The residue was dissolved in water and the pH was adjusted to 8 with aqueous potassium hydroxide, the product was collected by filtration and dried under vacuum to give ethyl 6-quinolinecarboxylate (9.85 g, 89% yield) as a light brown solid. Melting point: 66-67 ° C. TLC (unfolding agent: CH2Cl2/MeOH/AcOH = 9:0.5:0.1): Rf = 0.52. 2. Ethyl 6-quinolinecarboxylate (9.80 g, 48.7 mmol) was dissolved in an appropriate amount of solvent and the pH was adjusted to 2 with aqueous 1 N HCl. 20% Pd-Mohr catalyst (1.96 g) was added and hydrogenated at 60 °C and 3 bar hydrogen pressure for 17 h. The reaction was carried out over a 2.5 mmol glass tube. Upon completion of the reaction, the reaction mixture was filtered through diatomaceous earth. The filtrate was evaporated and the residue was dissolved in ethyl acetate and water and the pH was adjusted to 16 with 1N aqueous potassium hydroxide. the organic and aqueous phases were separated, the organic phase was washed with brine, dried over anhydrous Na2SO4 and the solvent was evaporated to give ethyl 1,2,3,4-tetrahydro-6-quinolinecarboxylate (8.72 g, 87% yield) as a light brown solid. Melting point: 68-70°C. GC-MS: [M+]=205.
References
[1] Patent: US2003/232868, 2003, A1. Location in patent: Page 15-16
[2] Patent: US2012/108619, 2012, A1. Location in patent: Page/Page column 36
[3] Patent: WO2007/89626, 2007, A2. Location in patent: Page/Page column 75-76
[4] Chemische Berichte, 1909, vol. 42, p. 4854
[5] Journal of the Chemical Society, 1948, p. 2008,2010
Quinoline-6-carboxylic acid ethyl ester Preparation Products And Raw materials
Raw materials
Preparation Products
Quinoline-6-carboxylic acid ethyl ester Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Longsheng chemical Co.,Ltd. | 58099637 13585536065 | sales@shlschem.com | China | 9880 | 59 |
| ZEROSCHEM.CO.,LTD. | 10-61256048 13810278579; | sales@zeroschem.com | China | 1399 | 59 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32273 | 50 |
| China DongFan Chemical Co.,LTD | 86-0571-85151182 | China | 5681 | 66 | |
| Beijing HengPuGao Pharmaceutical Chemistry Technology Co., Ltd. | 010-81520996 13439320863 | hengpugao@126.com | China | 159 | 57 |
| Shandong Xiya Chemical Co., Ltd | 13355009207 13355009207 | 3007715519@qq.com | China | 18722 | 57 |
| Chengdu Forest Science and Technology Development Co., Ltd. | 18030648795 18030648795 | sales@cdforestchem.com | China | 1998 | 58 |
| Shanghai civi chemical technology co.,Ltd | 86-21-34053660 | sale@labgogo.com | China | 9853 | 52 |
| Shanghai Topbiochem Technology Co., Ltd | +86-21-60341587 | sales@topbiochem.com | China | 6166 | 58 |
View Latest Price from Quinoline-6-carboxylic acid ethyl ester manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-20 | QUINOLINE-6-CARBOXYLIC ACID ETHYL ESTER
73987-38-9
|
$1.10 | 1g | 99.00% | 100 Tons | Dideu Industries Group Limited |
-
- QUINOLINE-6-CARBOXYLIC ACID ETHYL ESTER
73987-38-9
- $1.10
- 99.00%
- Dideu Industries Group Limited
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