4-Benzyloxy-2-methoxybenzaldehyde
- CAS No.
- 58026-14-5
- Chemical Name:
- 4-Benzyloxy-2-methoxybenzaldehyde
- Synonyms
- 4-Benzyloxy-o-anisaldehyde;5-(Benzyloxy)-2-formylanisole;4-Benzyloxy-2-methoxybenzaldehyde;2-methoxy-4-benzyloxybenzaldehyde;2-Methoxy-4-(phenylMethoxy)benzaldehyde;4-BENZYLOXY-2-METHOXYBENZALDEHYDE, 98+%;Benzaldehyde, 2-methoxy-4-(phenylmethoxy)-
- CBNumber:
- CB3683929
- Molecular Formula:
- C15H14O3
- Molecular Weight:
- 242.27
- MDL Number:
- MFCD01075699
- MOL File:
- 58026-14-5.mol
- MSDS File:
- SDS
| Melting point | 98-100°C |
|---|---|
| Boiling point | 180°C 2mm |
| Density | 1.154±0.06 g/cm3(Predicted) |
| Flash point | 180°C/2mm |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| Appearance | Light yellow to brown Solid |
| Sensitive | Air Sensitive |
| BRN | 1880700 |
| CAS DataBase Reference | 58026-14-5(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| Hazard Codes | Xi |
| Safety Statements | 22-24/25 |
| HS Code | 2912490090 |
4-Benzyloxy-2-methoxybenzaldehyde price More Price(37)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | FB18446 | 4-Benzyloxy-2-methoxybenzaldehyde | 58026-14-5 | 25g | $4262.5 | 2026-06-04 | Buy |
| Biosynth | FB18446 | 4-Benzyloxy-2-methoxybenzaldehyde | 58026-14-5 | 50g | $6875 | 2026-06-04 | Buy |
| Biosynth | FB18446 | 4-Benzyloxy-2-methoxybenzaldehyde | 58026-14-5 | 100g | $9213 | 2026-06-04 | Buy |
| Apolloscientific | OR14750 | 4-(Benzyloxy)-2-methoxybenzaldehyde 99% | 58026-14-5 | 1g | $21 | 2026-06-04 | Buy |
| Apolloscientific | OR14750 | 4-(Benzyloxy)-2-methoxybenzaldehyde 99% | 58026-14-5 | 5g | $56 | 2026-06-04 | Buy |
4-Benzyloxy-2-methoxybenzaldehyde Chemical Properties, Uses, Production
Synthesis
18278-34-7
100-39-0
58026-14-5
4-Hydroxy-2-methoxybenzaldehyde (200 mg, 1.31 mmol) was dissolved in N,N-dimethylformamide (DMF) under the protection of nitrogen (N2), potassium carbonate (K2CO3, 543 mg, 3.93 mmol) was added, and stirred for 30 min at room temperature. Subsequently, benzyl bromide (BnBr, 0.312 mL, 2.62 mmol) was added dropwise to the reaction mixture and stirring was continued for 1.5 hours. After completion of the reaction, the reaction mixture was diluted with ethyl acetate (EtOAc) and washed with deionized water (H2O). The organic phase was dried with anhydrous sodium sulfate (Na2SO4) and concentrated under reduced pressure. Purification by silica gel column chromatography with ethyl acetate/hexane (1:2, v/v) as eluent afforded the target product 4-benzyloxy-2-methoxybenzaldehyde (304 mg, 95.7% yield).1H-NMR (CDCl3, 400 MHz) δ: 7.81 (d, 1H, J = 8.6 Hz), 7.36 (m, 5H), 6.62 ( dd, 1H, J = 8.7, 2.2 Hz), 6.54 (d, 1H, J = 2.2 Hz), 5.14 (s, 2H), 3.89 (s, 3H).
References
[1] Molecules, 2015, vol. 20, # 9, p. 15966 - 15975
[2] Bioorganic and Medicinal Chemistry, 1998, vol. 6, # 9, p. 1429 - 1437
[3] Journal of the American Chemical Society, 2006, vol. 128, # 33, p. 10640 - 10641
[4] Patent: WO2006/40520, 2006, A1. Location in patent: Page/Page column 103
[5] Patent: WO2007/99326, 2007, A1. Location in patent: Page/Page column 111
4-Benzyloxy-2-methoxybenzaldehyde Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
4-Benzyloxy-2-methoxybenzaldehyde Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15813 | 69 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Chemsky (shanghai) International Co.,Ltd | 021-50135380 | shchemsky@sina.com | China | 15350 | 60 |
| Chembon Pharmaceutical Co., Ltd. | 028-84252981 18583719936 | sales@chembon.com.cn | China | 854 | 64 |
| Shanghai Aladdin Bio-Chem Technology Co.,LTD | 400-6206333 13167063860 | anhua.mao@aladdin-e.com | China | 29985 | 65 |
| Shanghai Raise Chemical Technology Co.,Ltd | 15026594951 | rs@raise-chem.com | China | 4905 | 55 |
| Shanghai Raise Chemical Technology Co.,Ltd | +86-021-50935922 | China | 7854 | 55 |
