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ChemicalBook >> CAS DataBase List >>2,4-Dichloropyrido[2,3-d]pyrimidine

2,4-Dichloropyrido[2,3-d]pyrimidine

2,4-Dichloropyrido[2,3-d]pyrimidine Structure
2,4-Dichloropyrido[2,3-d]pyrimidine structure
CAS No.
126728-20-9
Chemical Name:
2,4-Dichloropyrido[2,3-d]pyrimidine
Synonyms
2,4-dichloropyrido[2,3-d]...;2,4-DICHLOROPYRIDO[2,3-D]PYRIMIDINE;Pyrido[2,3-d]pyrimidine,2,4-dichloro-;2,4-Dichloro-pyrido[2,3-d]pyrimidine2,4-Dichloro-pyrido[2,3-d]pyrimidine
CBNumber:
CB3696084
Molecular Formula:
C7H3Cl2N3
Molecular Weight:
200.02
MDL Number:
MFCD07644627
MOL File:
126728-20-9.mol
MSDS File:
SDS
Last updated:2026-05-28 04:33:41
Request For Quotation

2,4-Dichloropyrido[2,3-d]pyrimidine Properties

Melting point 157-158 °C (decomp)
Density 1.573±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
pka -0.38±0.30(Predicted)
Appearance White to off-white Solid
InChI InChI=1S/C7H3Cl2N3/c8-5-4-2-1-3-10-6(4)12-7(9)11-5/h1-3H
InChIKey QSNSZGYDLUPWSV-UHFFFAOYSA-N
SMILES C1(Cl)=NC(Cl)=C2C=CC=NC2=N1

SAFETY

Risk and Safety Statements

Symbol(GHS)  Skull and Crossbones (GHS06)
GHS06
Signal word  Danger
Hazard statements  H301
Precautionary statements  P264-P270-P301+P310-P321-P330-P405-P501

2,4-Dichloropyrido[2,3-d]pyrimidine price More Price(58)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
AstaTech 60470 2,4-DICHLOROPYRIDO[2,3-D]PYRIMIDINE 95% 126728-20-9 1G $37 2026-04-30 Buy
AstaTech 60470 2,4-DICHLOROPYRIDO[2,3-D]PYRIMIDINE 95% 126728-20-9 5G $177 2026-04-30 Buy
AstaTech 60470 2,4-DICHLOROPYRIDO[2,3-D]PYRIMIDINE 95% 126728-20-9 25G $599 2026-04-30 Buy
Biosynth FD31600 2,4-Dichloropyrido [2,3-D] pyrimidine 126728-20-9 50g $4082 2026-06-04 Buy
Biosynth FD31600 2,4-Dichloropyrido [2,3-D] pyrimidine 126728-20-9 100g $6712 2026-06-04 Buy
Product number Packaging Price Buy
60470 1G $37 Buy
60470 5G $177 Buy
60470 25G $599 Buy
FD31600 50g $4082 Buy
FD31600 100g $6712 Buy

2,4-Dichloropyrido[2,3-d]pyrimidine Chemical Properties, Uses, Production

Reactivity Profile

Selective disubstitution of 2,4-dichloropyrido[2,3-d]pyrimidine with various nucleophiles was investigated by Lavecchia et al. Suzuki and Stille cross-coupling reactions on monosubstituted compound 4-tert-butylamino-2-chloro-pyrido[2,3-d]pyrimidine were performed in high yields. ,4-dichloropyrido[2,3-d]pyrimidine was easily substituted at position 4 with different nucleophiles. This position was more reactive than position 2, as in simple pyrimidinic systems. 2,4-dichloropyrido[2,3-d]pyrimidine 3 was prepared from 2-aminonicotinic acid 1 via 2,4-dihydroxypyrido[2,3-d]pyrimidine 2 following Robin and Hitchings method.
2,4-DICHLOROPYRIDO[2,3-D]PYRIMIDINE

Synthesis

2,4-dichloropyrido[2,3-d]pyrimidine 3 was prepared from 2-aminonicotinic acid 1 via 2,4-dihydroxypyrido[2,3-d]pyrimidine 2 following Robin and Hitchings method[1].
2,4-DICHLOROPYRIDO[2,3-D]PYRIMIDINE

References

[1] G. Lavecchia, G. Guillaumet, S. Berteina-Raboin. “Selective bifunctionalization of pyrido[2,3-d]pyrimidines in positions 2 and 4 by SNAr and palladium-catalyzed coupling reactions.” Tetrahedron Letters 46 35 (2005): Pages 5851-5855.

2,4-Dichloropyrido[2,3-d]pyrimidine Preparation Products And Raw materials

Raw materials

Pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione

Preparation Products

4-(2-Chloropyrido[2,3-d]pyrimidin-4-yl)morpholine

2,4-Dichloropyrido[2,3-d]pyrimidine Suppliers

Global Suppliers ( 170)
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Wuhan Chemwish Technology Co., Ltd 86-027-67849912 sales@chemwish.com China 35884 56
Shanghai Sinch Parmaceuticals Tech. Co. Ltd. +86-21-54098501 sales@sinch.com.cn China 11592 64
Jia Xing Isenchem Co.,Ltd 0573-85285100 18627885956 isenchem@163.com China 9389 66
Shangchem Co., Ltd. +86-21-68182121 China 881 52
Accela ChemBio Co.,Ltd. 021-50795510 4000665055 marketing@accelachem.com China 10972 64
Nanjing Chemlin Chemical Co., Ltd 025-83697070 13770331960 info@chemlin.com.cn China 16305 64
skychemical Co.Ltd 021-20958197 20965099 sales@skychemical.com China 1182 57
Shanghai AmasPharm Co., Ltd. 021-54540637 18621091017 sales@amaspharm.com China 787 62
SpringPharma Tech Co.,Ltd +86-25-68710855, +86-25-68710897 sales@springpharma.net China 1260 62
Supplier Advantage
J & K SCIENTIFIC LTD. 76
Wuhan Chemwish Technology Co., Ltd 56
Shanghai Sinch Parmaceuticals Tech. Co. Ltd. 64
Jia Xing Isenchem Co.,Ltd 66
Shangchem Co., Ltd. 52
Accela ChemBio Co.,Ltd. 64
Nanjing Chemlin Chemical Co., Ltd 64
skychemical Co.Ltd 57
Shanghai AmasPharm Co., Ltd. 62
SpringPharma Tech Co.,Ltd 62

View Latest Price from 2,4-Dichloropyrido[2,3-d]pyrimidine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2,4-DICHLOROPYRIDO[2,3-D]PYRIMIDINE pictures 2021-07-13 2,4-DICHLOROPYRIDO[2,3-D]PYRIMIDINE
126728-20-9
 $10.00-15.00 1KG 99%+ HPLC Zhuozhou Wenxi import and Export Co., Ltd
2,4-DICHLOROPYRIDO[2,3-D]PYRIMIDINE pictures 2021-07-10 2,4-DICHLOROPYRIDO[2,3-D]PYRIMIDINE
126728-20-9
 $10.00-15.00 1KG 99%+ HPLC Zhuozhou Wenxi import and Export Co., Ltd
2,4-Dichloropyrido[2,3-d]pyrimidine pictures 2020-05-15 2,4-Dichloropyrido[2,3-d]pyrimidine
126728-20-9
 $1.00 1KG 99% 20T Shaanxi Dideu Medichem Co. Ltd

2,4-Dichloropyrido[2,3-d]pyrimidine Spectrum

2,4-DICHLOROPYRIDO[2,3-D]PYRIMIDINE(126728-20-9)1HNMR

126728-20-9 (2,4-Dichloropyrido[2,3-d]pyrimidine) Related Search:

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2,4-dichloropyrido[2,3-d]... Pyrido[2,3-d]pyrimidine,2,4-dichloro- 2,4-DICHLOROPYRIDO[2,3-D]PYRIMIDINE 2,4-Dichloro-pyrido[2,3-d]pyrimidine2,4-Dichloro-pyrido[2,3-d]pyrimidine 126728-20-9 C7H3Cl2N3