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Boc-Trp-OBzl

Boc-Trp-OBzl Structure
Boc-Trp-OBzl structure
CAS No.
57229-67-1
Chemical Name:
Boc-Trp-OBzl
Synonyms
Boc-Trp-OBzl;Boc-L-Trp-OBzl;BOC-L-TRYPTOPHAN BENZYL ESTER;(Tert-Butoxy)Carbonyl Trp-OBzl;N-a-Boc-L-Tryptophanbenzylester;Nα-Boc-L-tryptophan benzyl ester;N-α-Boc-L-Tryptophan benzyl ester;N-Boc-L-tryptophanbenzylester,95%;N-.ALPHA.-BOC-L-TRYPTOPHAN BENZYL ESTER;Trit-butoxycarbonyl-tryptophan benzyl ester
CBNumber:
CB3751758
Molecular Formula:
C23H26N2O4
Molecular Weight:
394.46
MDL Number:
MFCD00190837
MOL File:
57229-67-1.mol
MSDS File:
SDS
Last updated:2026-09-12 18:52:11
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Boc-Trp-OBzl Properties

Melting point 140-146℃
Boiling point 591.0±50.0 °C(Predicted)
Density 1.205±0.06 g/cm3(Predicted)
storage temp. 2-8°C
form Powder
pka 11.14±0.46(Predicted)
color Off-white to white

Boc-Trp-OBzl price More Price(30)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological 285733 Na-Boc-L-tryptophan benzyl ester Asreported 57229-67-1 5g $389 2026-06-03 Buy
Usbiological 285733 Na-Boc-L-tryptophan benzyl ester Asreported 57229-67-1 10g $593 2026-06-03 Buy
Usbiological 285733 Na-Boc-L-tryptophan benzyl ester Asreported 57229-67-1 25g $837 2026-06-03 Buy
Usbiological 240336 Na-Boc-L-tryptophan benzyl ester 98+% (HPLC) ≥98%(HPLC) 57229-67-1 1g $173 2026-06-03 Buy
Usbiological 240336 Na-Boc-L-tryptophan benzyl ester 98+% (HPLC) ≥98%(HPLC) 57229-67-1 5g $233 2026-06-03 Buy
Product number Packaging Price Buy
285733 5g $389 Buy
285733 10g $593 Buy
285733 25g $837 Buy
240336 1g $173 Buy
240336 5g $233 Buy

Boc-Trp-OBzl Chemical Properties, Uses, Production

Chemical Properties

White to off-white powder

Synthesis

Benzyl bromide

100-39-0

N-[(tert-Butoxy)carbonyl]-L-tryptophan

13139-14-5

BOC-TRP-OBZL

57229-67-1

General procedure for the synthesis of N-tert-butoxycarbonyl-O-benzyl-L-tryptophan from benzyl bromide and (S)-2-((tert-butoxycarbonyl)amino)-3-(1H-indol-3-yl)propanoic acid: to a solution of methyl (S)-2-((tert-butoxycarbonyl)amino)-3-(1H-indol-3-yl)propanoate (2 g, 6.57 mmol) in DMF (27 mL) K2CO3 (2.27 g, 16.5 mmol) and benzyl bromide (811 μL, 6.83 mmol) were added to it. The reaction mixture was stirred at room temperature for 12 hours. After completion of the reaction, the reaction was quenched with saturated aqueous NaHCO3 solution. The reaction mixture was diluted with EtOAc (10 mL) and washed with aqueous NH4Cl to separate the organic and aqueous layers. The aqueous layer was extracted with EtOAc (3 x 10 mL), the organic layers were combined, washed with brine (3 x 15 mL), dried over anhydrous Na2SO4, filtered and concentrated under reduced pressure. A white powdery product (2.1 g, 81% yield) was obtained by recrystallization from cyclohexane with a melting point of 140 °C. The spectral data of the product were in agreement with those reported in the literature.1H NMR (250 MHz, CDCl3): δ=8.00 (br s, 1H), 7.56 (d, J=8.3 Hz, 1H), 7.38-7.30 (m, 4H), 7.29-7.17 (m, 3H), 7.16-7.07 (m, 1H), 6.81 (s, 1H), and 5.09 (d, J=3.7Hz, 2H), 4.79-4.61 (m, 1H), 3.29 (d, J=5.3Hz, 2H), 1.43 (s, 9H).

References

[1] Organic and Biomolecular Chemistry, 2013, vol. 11, # 10, p. 1594 - 1597
[2] Journal of Organic Chemistry, 2014, vol. 79, # 23, p. 11549 - 11557
[3] Tetrahedron Letters, 2009, vol. 50, # 26, p. 3645 - 3647
[4] Synthesis (Germany), 2017, vol. 49, # 2, p. 391 - 396
[5] Carbohydrate Research, 1981, vol. 89, p. 229 - 236

Boc-Trp-OBzl Preparation Products And Raw materials

Raw materials

Benzyl bromide N-[(tert-Butoxy)carbonyl]-L-tryptophan Potassium carbonate N,N-Dimethylformamide

Preparation Products

Boc-Trp-OBzl Suppliers

Global Suppliers ( 59)
Supplier Tel Email Country ProdList Advantage
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
Beijing HuaMeiHuLiBiological Chemical 010-56205725 waley188@sohu.com China 12323 58
NINGBO INNO PHARMCHEM CO.,LTD. 86-574-27787657 info@dearchem.com China 4607 58
Shanghai GL Peptide Ltd. +86-21-61263310 13764994101 fisherwang@glschina.com China 8059 55
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
Wuxi Asia Peptide Biotechnology Limited Company 0510-83583050 13771062561 willsun@peptide-search.com China 6713 58
Nanjing Peptide Biotech Ltd. 025-58361106-805 15951641583 zhao.xu@njpeptide.com China 9976 55
9ding chemical ( Shanghai) Limited 021-021-52271985 17721149837 sales@9dingchem.com China 19780 60
Aikon International Limited 025-66113011 19370895928 qzhang@aikonchem.com China 15390 58
Shanghai Jizhi Biochemical Technology Co. Ltd. 021-4009004166/18616739031 18616739031 3007523370@qq.com China 40000 58
Supplier Advantage
Shanghai Hanhong Scientific Co.,Ltd. 64
Beijing HuaMeiHuLiBiological Chemical 58
NINGBO INNO PHARMCHEM CO.,LTD. 58
Shanghai GL Peptide Ltd. 55
Shanghai YuanYe Biotechnology Co., Ltd. 60
Wuxi Asia Peptide Biotechnology Limited Company 58
Nanjing Peptide Biotech Ltd. 55
9ding chemical ( Shanghai) Limited 60
Aikon International Limited 58
Shanghai Jizhi Biochemical Technology Co. Ltd. 58

View Latest Price from Boc-Trp-OBzl manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
BOC-TRP-OBZL pictures 2020-01-19 BOC-TRP-OBZL
57229-67-1
 $1.00 1KG 99.0% 100kg Career Henan Chemical Co

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BOC-L-TRYPTOPHAN BENZYL ESTER N-α-Boc-L-Tryptophan benzyl ester N-a-Boc-L-Tryptophanbenzylester N-.ALPHA.-BOC-L-TRYPTOPHAN BENZYL ESTER (S)-benzyl 2-(tert-butoxycarbonylamino)-3-(1H-indol-3-yl)propanoate (S)-2-tert-Butoxycarbonylamino-3-(-1H-indol-3-yl)propionic acid benzyl ester Boc-L-Trp-OBzl Nα-Boc-L-tryptophan benzyl ester≥ 99% (HPLC) N-ALPHA-T-BUTOXYCARBONYL-L-TRYPTOPHAN BENZYL ESTER N-tert-Butoxycarbonyl-L-tryptophan benzyl ester (Tert-Butoxy)Carbonyl Trp-OBzl benzyl (2S)-2-{[(tert-butoxy)carbonyl]amino}-3-(1H-indol-3-yl)propanoate L-Tryptophan, N-[(1,1-dimethylethoxy)carbonyl]-, phenylmethyl ester N-Boc-L-tryptophanbenzylester,95% Nα-Boc-L-tryptophan benzyl ester Trit-butoxycarbonyl-tryptophan benzyl ester Boc-Trp-OBzl 57229-67-1