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HEXANOIC ANHYDRIDE

CAS No.
2051-49-2
Chemical Name:
HEXANOIC ANHYDRIDE
Synonyms
N-HEXANOIC ANHYDRIDE;CAPROIC ANHYDRIDE;hexanoylhexanoate;N-HEXOIC ANHYDRIDE;Capronic anhydride;Hexanoyl anhydride;n-Capriocanhydride;HEXANOIC ANHYDRIDE;N-CAPROIC ANHYDRIDE;N-CAPRONIC ANHYDRIDE
CBNumber:
CB3766110
Molecular Formula:
C12H22O3
Molecular Weight:
214.3
MDL Number:
MFCD00009509
MOL File:
2051-49-2.mol
MSDS File:
SDS
Last updated:2026-01-13 11:20:04
Product description Number Pack Size Price
Hexanoic anhydride 97% 194530 50g $46.17
Hexanoic anhydride purum, ≥97.0% (GC) 21580 250ML $73.3
Hexanoic anhydride 97% 194530 250g $94.8
Hexanoic anhydride purum, ≥97.0% (GC) 21580 50mL $33
Hexanoic Anhydride >96.0%(GC) C0021 25mL $18
More product size

HEXANOIC ANHYDRIDE Properties

Melting point -40 °C
Boiling point 246-248 °C (lit.)
Density 0.928 g/mL at 20 °C (lit.)
vapor pressure 2.9Pa at 25℃
refractive index n20/D 1.428(lit.)
Flash point >230 °F
storage temp. Store below +30°C.
solubility ethanol: soluble1g/10 mL, clear, colorless
form Liquid
color Clear colorless to light yellow
explosive limit 0.7%(V)
Water Solubility Hydrolyzes in water.
Sensitive Moisture Sensitive
BRN 1776561
InChI 1S/C12H22O3/c1-3-5-7-9-11(13)15-12(14)10-8-6-4-2/h3-10H2,1-2H3
InChIKey PKHMTIRCAFTBDS-UHFFFAOYSA-N
SMILES CCCCCC(=O)OC(=O)CCCCC
LogP 4.45 at 25℃
CAS DataBase Reference 2051-49-2(CAS DataBase Reference)
FDA UNII GG70Y8LTBY
EPA Substance Registry System Hexanoic acid, anhydride (2051-49-2)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS05
Signal word  Danger
Hazard statements  H314
Precautionary statements  P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363-P405
PPE Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
Hazard Codes  C
Risk Statements  34
Safety Statements  26-36/37/39-45
RIDADR  UN 3265 8/PG 2
WGK Germany  3
TSCA  TSCA listed
HazardClass  8
PackingGroup  III
HS Code  29159000
Storage Class 8A - Combustible corrosive hazardous materials
Hazard Classifications Skin Corr. 1B
Limited Quantities 1.0 L (0.3 gallons) (liquid) or 1 Kg (2.2 lbs) (solid)
Excepted Quantities Max Inner Pack (30g or 30ml) and Max Outer Pack (500g or 500ml)
NFPA 704
1
3 0

HEXANOIC ANHYDRIDE price More Price(15)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 194530 Hexanoic anhydride 97% 2051-49-2 50g $46.17 2025-07-31 Buy
Sigma-Aldrich 21580 Hexanoic anhydride purum, ≥97.0% (GC) 2051-49-2 250ML $73.3 2025-07-31 Buy
Sigma-Aldrich 194530 Hexanoic anhydride 97% 2051-49-2 250g $94.8 2025-07-31 Buy
Sigma-Aldrich 21580 Hexanoic anhydride purum, ≥97.0% (GC) 2051-49-2 50mL $33 2023-06-20 Buy
TCI Chemical C0021 Hexanoic Anhydride >96.0%(GC) 2051-49-2 25mL $18 2025-07-31 Buy
Product number Packaging Price Buy
194530 50g $46.17 Buy
21580 250ML $73.3 Buy
194530 250g $94.8 Buy
21580 50mL $33 Buy
C0021 25mL $18 Buy

HEXANOIC ANHYDRIDE Chemical Properties,Uses,Production

Chemical Properties

clear colorless to light yellow liquid

Uses

Hexanoic anhydride has been used in:

  • green synthesis of esters of acyclovir (acyclovir prodrugs)
  • preparation of hexanoyl-modified chitosan nanoparticles and chitosan-based polymeric surfactants via N-acylation of chitosans

Uses

Hexanoic anhydride was used in:

  • green synthesis of esters of acyclovir (acyclovir prodrugs)
  • preparation of hexanoyl-modified chitosan nanoparticles
  • preparation of chitosan-based polymeric surfactants via N-acylation of chitosans

Uses

Hexanoic Anhydride, is used as a reactant in the total synthesis of acremomannolipin A via steroselective β-mannosylation of 4,6,-O-benzylidene-protected mannosyl sulfoxide with a D-mannitol derivative.

Preparation

To an ice-cooled flask containing 116 gm (1.0 mole) of n-caproic acid is added 21.0-23.10 gm (0.5-0.55 mole) of ketene at a rate of 0.45 mole/hr. The reaction mixture is fractionally distilled at atmospheric pressure to afford a forecut of acetone, acetic acid, and acetic anhydride. The oil bath is raised to 220°C over a 1-hr period, kept there for 3 hr to ensure complete removal of acetic acid, and then cooled. The distillation is continued under reduced pressure to afford 86-95 gm (80-87%), b.p. 109- 112°C (3 mm Hg) and b.p. 118-121°C (6 mm Hg).
Preparation of n-Caproic Anhydride

Flammability and Explosibility

Not classified

HEXANOIC ANHYDRIDE Preparation Products And Raw materials

Global( 214)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Chuanghai Biotechnology Co,.LTD
+86-13131129325 sales1@chuanghaibio.com China 5242 58
Hebei Chuanghai Biotechnology Co., Ltd
+8615531151365 mina@chuanghaibio.com China 18126 58
Shanghai Zheyan Biotech Co., Ltd.
18017610038 zheyansh@163.com CHINA 3619 58
career henan chemical co
+86-0371-86658258 +8613203830695 factory@coreychem.com China 29795 58
Hefei TNJ Chemical Industry Co.,Ltd.
+86-0551-65418671 +8618949823763 sales@tnjchem.com China 34563 58
Shanghai UCHEM Inc.
+862156762820 +86-13564624040 sales@myuchem.com China 8731 58
ANHUI WITOP BIOTECH CO., LTD
+8615255079626 eric@witopchemical.com China 23541 58
Dideu Industries Group Limited
+86-29-89586680 +86-15129568250 1026@dideu.com China 19282 58
Dayang Chem (Hangzhou) Co.,Ltd.
+86-0571-88938639 +8617705817739 info@dycnchem.com China 52846 58
GLR Innovations
+91 9891111994 info@glrgroup.in India 4535 58

View Lastest Price from HEXANOIC ANHYDRIDE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
HEXANOIC ANHYDRIDE pictures 2025-12-01 HEXANOIC ANHYDRIDE
2051-49-2
US $0.00-0.00 / KG 1KG 98.0% 10000KGS Shaanxi Dideu New Materials Co. Ltd
Hexanoic anhydride pictures 2025-06-27 Hexanoic anhydride
2051-49-2
US $0.00-0.00 / KG 50KG 99% 500000kg Hebei Chuanghai Biotechnology Co., Ltd
Hexanoic Anhydride pictures 2025-05-26 Hexanoic Anhydride
2051-49-2
US $5.00-2.00 / KG 1KG 99% 10000kg Hebei Chuanghai Biotechnology Co,.LTD
N-BUTYLACETIC ANHYDRIDE N-CAPRONIC ANHYDRIDE N-CAPROIC ANHYDRIDE N-HEXANOIC ANHYDRIDE N-HEXOIC ANHYDRIDE PENTYLFORMIC ANHYDRIDE N-CAPROICANHYDRIDE=HEXANOICANHYDRIDE Bis(hexanoic)anhydride Biscaproic anhydride Bishexanoic anhydride Dihexanoic anhydride Hexanoic anhydride,97% Hexanoic anhydride, 97% 250GR Hexanoic anhydride, 97% 50GR Hexanoic acid,1,1'-anhydride Hexanoic anhydride 97% Caproic acid anhydride Capronic acid anhydride Capronic anhydride hexanoicacid,anhydride Hexanoicacidanhydride Hexanoyl anhydride n-Capriocanhydride n-Hexanoic acid anhydride HEXANOIC ANHYDRIDE CAPROIC ANHYDRIDE 6-benzamido-2-bromohexanoic acid Hexanoic Anhydride > hexanoylhexanoate HEXANOIC ANHYDRIDE ISO 9001:2015 REACH High Quality HEXANOIC ANHYDRIDE CAS 2051-49-2 with Free sample 2051-49-2 C12H22O3 CH3CH24CO2O C5H11CO2O Carboxylic Acid Anhydrides Carbonyl Compounds Building Blocks Organic Building Blocks Pharmaceutical Intermediates