HEXANOIC ANHYDRIDE
- CAS No.
- 2051-49-2
- Chemical Name:
- HEXANOIC ANHYDRIDE
- Synonyms
- N-HEXANOIC ANHYDRIDE;CAPROIC ANHYDRIDE;hexanoylhexanoate;N-HEXOIC ANHYDRIDE;Capronic anhydride;Hexanoyl anhydride;n-Capriocanhydride;HEXANOIC ANHYDRIDE;N-CAPROIC ANHYDRIDE;N-CAPRONIC ANHYDRIDE
- CBNumber:
- CB3766110
- Molecular Formula:
- C12H22O3
- Molecular Weight:
- 214.3
- MDL Number:
- MFCD00009509
- MOL File:
- 2051-49-2.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| Hexanoic anhydride 97% | 194530 | 50g | $46.17 |
| Hexanoic anhydride purum, ≥97.0% (GC) | 21580 | 250ML | $73.3 |
| Hexanoic anhydride 97% | 194530 | 250g | $94.8 |
| Hexanoic anhydride purum, ≥97.0% (GC) | 21580 | 50mL | $33 |
| Hexanoic Anhydride >96.0%(GC) | C0021 | 25mL | $18 |
| More product size | |||
| Melting point | -40 °C |
|---|---|
| Boiling point | 246-248 °C (lit.) |
| Density | 0.928 g/mL at 20 °C (lit.) |
| vapor pressure | 2.9Pa at 25℃ |
| refractive index |
n |
| Flash point | >230 °F |
| storage temp. | Store below +30°C. |
| solubility | ethanol: soluble1g/10 mL, clear, colorless |
| form | Liquid |
| color | Clear colorless to light yellow |
| explosive limit | 0.7%(V) |
| Water Solubility | Hydrolyzes in water. |
| Sensitive | Moisture Sensitive |
| BRN | 1776561 |
| InChI | 1S/C12H22O3/c1-3-5-7-9-11(13)15-12(14)10-8-6-4-2/h3-10H2,1-2H3 |
| InChIKey | PKHMTIRCAFTBDS-UHFFFAOYSA-N |
| SMILES | CCCCCC(=O)OC(=O)CCCCC |
| LogP | 4.45 at 25℃ |
| CAS DataBase Reference | 2051-49-2(CAS DataBase Reference) |
| FDA UNII | GG70Y8LTBY |
| EPA Substance Registry System | Hexanoic acid, anhydride (2051-49-2) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS05 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H314 | |||||||||
| Precautionary statements | P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363-P405 | |||||||||
| PPE | Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter | |||||||||
| Hazard Codes | C | |||||||||
| Risk Statements | 34 | |||||||||
| Safety Statements | 26-36/37/39-45 | |||||||||
| RIDADR | UN 3265 8/PG 2 | |||||||||
| WGK Germany | 3 | |||||||||
| TSCA | TSCA listed | |||||||||
| HazardClass | 8 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29159000 | |||||||||
| Storage Class | 8A - Combustible corrosive hazardous materials | |||||||||
| Hazard Classifications | Skin Corr. 1B | |||||||||
| Limited Quantities | 1.0 L (0.3 gallons) (liquid) or 1 Kg (2.2 lbs) (solid) | |||||||||
| Excepted Quantities | Max Inner Pack (30g or 30ml) and Max Outer Pack (500g or 500ml) | |||||||||
| NFPA 704 |
|
HEXANOIC ANHYDRIDE price More Price(15)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 194530 | Hexanoic anhydride 97% | 2051-49-2 | 50g | $46.17 | 2025-07-31 | Buy |
| Sigma-Aldrich | 21580 | Hexanoic anhydride purum, ≥97.0% (GC) | 2051-49-2 | 250ML | $73.3 | 2025-07-31 | Buy |
| Sigma-Aldrich | 194530 | Hexanoic anhydride 97% | 2051-49-2 | 250g | $94.8 | 2025-07-31 | Buy |
| Sigma-Aldrich | 21580 | Hexanoic anhydride purum, ≥97.0% (GC) | 2051-49-2 | 50mL | $33 | 2023-06-20 | Buy |
| TCI Chemical | C0021 | Hexanoic Anhydride >96.0%(GC) | 2051-49-2 | 25mL | $18 | 2025-07-31 | Buy |
HEXANOIC ANHYDRIDE Chemical Properties,Uses,Production
Chemical Properties
clear colorless to light yellow liquid
Uses
Hexanoic anhydride has been used in:
- green synthesis of esters of acyclovir (acyclovir prodrugs)
- preparation of hexanoyl-modified chitosan nanoparticles and chitosan-based polymeric surfactants via N-acylation of chitosans
Uses
Hexanoic anhydride was used in:
- green synthesis of esters of acyclovir (acyclovir prodrugs)
- preparation of hexanoyl-modified chitosan nanoparticles
- preparation of chitosan-based polymeric surfactants via N-acylation of chitosans
Uses
Hexanoic Anhydride, is used as a reactant in the total synthesis of acremomannolipin A via steroselective β-mannosylation of 4,6,-O-benzylidene-protected mannosyl sulfoxide with a D-mannitol derivative.
Preparation
To an ice-cooled flask containing 116 gm (1.0 mole) of n-caproic acid is added 21.0-23.10 gm (0.5-0.55 mole) of ketene at a rate of 0.45 mole/hr. The reaction mixture is fractionally distilled at atmospheric pressure to afford a forecut of acetone, acetic acid, and acetic anhydride. The oil bath is raised to 220°C over a 1-hr period, kept there for 3 hr to ensure complete removal of acetic acid, and then cooled. The distillation is continued under reduced pressure to afford 86-95 gm (80-87%), b.p. 109- 112°C (3 mm Hg) and b.p. 118-121°C (6 mm Hg).
Flammability and Explosibility
Not classified
HEXANOIC ANHYDRIDE Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | sales1@chuanghaibio.com | China | 5242 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615531151365 | mina@chuanghaibio.com | China | 18126 | 58 |
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3619 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29795 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| Shanghai UCHEM Inc. | +862156762820 +86-13564624040 | sales@myuchem.com | China | 8731 | 58 |
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | eric@witopchemical.com | China | 23541 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 19282 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52846 | 58 |
| GLR Innovations | +91 9891111994 | info@glrgroup.in | India | 4535 | 58 |
View Lastest Price from HEXANOIC ANHYDRIDE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2025-12-01 | HEXANOIC ANHYDRIDE
2051-49-2
|
US $0.00-0.00 / KG | 1KG | 98.0% | 10000KGS | Shaanxi Dideu New Materials Co. Ltd | |
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2025-06-27 | Hexanoic anhydride
2051-49-2
|
US $0.00-0.00 / KG | 50KG | 99% | 500000kg | Hebei Chuanghai Biotechnology Co., Ltd | |
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2025-05-26 | Hexanoic Anhydride
2051-49-2
|
US $5.00-2.00 / KG | 1KG | 99% | 10000kg | Hebei Chuanghai Biotechnology Co,.LTD |
-

- HEXANOIC ANHYDRIDE
2051-49-2
- US $0.00-0.00 / KG
- 98.0%
- Shaanxi Dideu New Materials Co. Ltd
-

- Hexanoic anhydride
2051-49-2
- US $0.00-0.00 / KG
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-

- Hexanoic Anhydride
2051-49-2
- US $5.00-2.00 / KG
- 99%
- Hebei Chuanghai Biotechnology Co,.LTD
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