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COTTONSEED OIL

CAS No.
8001-29-4
Chemical Name:
COTTONSEED OIL
Synonyms
cotton;LIPEX 109;cottonoil;nci-c50168;cottondoil;COTTONSEED OIL;Oils, cottonseed;COTTONSEEDOIL,NF;Baumwollsamenoel;cottonseedoilacid
CBNumber:
CB3773501
Molecular Formula:
CH4
Molecular Weight:
16.04246
MDL Number:
MFCD00130872
MOL File:
8001-29-4.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-08-25 20:17:46

COTTONSEED OIL Properties

Density 0.91
refractive index n20/D 1.471
Flash point 113 °C
storage temp. 2-8°C
solubility Slightly soluble in ethanol (95%); miscible with carbon disulfide, chloroform, ether, hexane, and petroleum ether.
form Oil
color Yellow
Odor at 100.00%. bland
biological source plant (Gossypium hirsutum L.)
Dielectric constant 1.3-1.4(0.0℃)
Stability Stable. Combustible. Incompatible with strong oxidizing agents. Heat and light sensitive.
Major Application pharmaceutical (small molecule)
Cosmetics Ingredients Functions SLIP MODIFIER
OPACIFYING
ABSORBENT
FRAGRANCE
SKIN CONDITIONING - MISCELLANEOUS
ANTICAKING
BULKING
SKIN CONDITIONING
Cosmetic Ingredient Review (CIR) COTTONSEED OIL (8001-29-4)
Indirect Additives used in Food Contact Substances COTTONSEED OIL
FDA 21 CFR 175.300; 176.210; 177.2800
EWG's Food Scores 1
FDA UNII H3E878020N
EPA Substance Registry System Cottonseed oil (8001-29-4)
UNSPSC Code 12352211
NACRES NA.25

SAFETY

Risk and Safety Statements

Safety Statements  24/25
WGK Germany  -
RTECS  GN2815000
8
TSCA  TSCA listed
HS Code  15122900
Storage Class 11 - Combustible Solids
Hazardous Substances Data 8001-29-4(Hazardous Substances Data)
NFPA 704
1
0 0

COTTONSEED OIL price More Price(19)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich PHR2976 Cottonseed Oil pharmaceutical secondary standard, certified reference material 8001-29-4 1G $107 2026-04-30 Buy
Sigma-Aldrich C7767 Cottonseed oil 8001-29-4 1l $70.4 2026-04-30 Buy
Sigma-Aldrich 1150207 Cottonseed oil 8001-29-4 1g $443 2026-04-30 Buy
Sigma-Aldrich 47113 Cottonseed oil analytical standard 8001-29-4 1000mg $60.8 2022-05-15 Buy
ChemScene CS-0040435 Cottonseed oil 99.12% 8001-29-4 100mL $27 2026-06-04 Buy
Product number Packaging Price Buy
PHR2976 1G $107 Buy
C7767 1l $70.4 Buy
1150207 1g $443 Buy
47113 1000mg $60.8 Buy
CS-0040435 100mL $27 Buy

COTTONSEED OIL Chemical Properties,Uses,Production

Chemical Properties

pale yellow liquid

Chemical Properties

Pale yellow or bright golden yellow-colored, clear oily liquid. It is odorless, or nearly so, with a bland, nutty taste. At temperatures below 10°C particles of solid fat may separate from the oil, and at about–5 to 10°C the oil becomes solid or nearly so.If it solidifies,the oil should be remelted and thoroughly mixed before use.

Uses

Pharmaceutic aid (solvent).

Uses

Cottonseed oil is a naturally occurring vegetable oil with insecticidal properties. It was used in the analysis of a calcimine compound.

Uses

Cottonseed oil has been used as an nutritional supplement for alveolar septal wall thickness in mice. It has been used to study its effects on indirect gestational and lactational exposure in rats.

Definition

Extractives and their physically modified derivatives. It consists primarily of the glycerides of the fatty acids linoleic, oleic and palmitic.

Production Methods

Cottonseed oil is the refined fixed oil obtained from the seed of cultivated varieties of Gossypium hirsutum Linne or of other species of Gossypium (Fam. Malvaceae). The seeds contain about 15% oil. The testae of the seeds are first separated and the kernels are then exposed to powerful expression in a hydraulic press. The crude oil thus obtained has a bright red or blackish-red color and requires purification before it is suitable for food or pharmaceutical purposes.
Cottonseed oil is refined by treatment with diluted alkali to neutralize acids, decolorized with fuller’s earth or activated carbon, deodorized with steam under reduced pressure, and chilled to separate glycerides and resinous substances of higher melting point.

General Description

Odorless colorless to pale-yellow liquid. Less dense than water and insoluble in water. Hence floats on water. Freezing point 32°F. Contains principally the glycerides of palmitic, oleic and linoleic acids.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

COTTONSEED OIL is sensitive to heat and light.

Health Hazard

None; is used as a food.

Fire Hazard

COTTONSEED OIL is combustible.

Pharmaceutical Applications

Cottonseed oil is used in pharmaceutical formulations primarily as a solvent for intramuscular injections. It has been used in intravenous emulsions as a fat source in parenteral nutrition regimens, although its use for this purpose has been superseded by soybean oil emulsions. It has also been used as an adjuvant in cholecystography and as a pediculicide and acaricide. It has the nutritive and emollient properties of fixed vegetable oils. By virtue of its high content of unsaturated acid glycerides (especially linoleic acid), it is used for dietary control of blood cholesterol levels in the prophylaxis and treatment of atherosclerosis. It is used as a solvent and vehicle for injections; as an emollient vehicle for other medications; and orally as a mild cathartic (in a dose of 30mL or more). It can also retard gastric secretion and motility, and increase caloric intake. It has been used in the manufacture of soaps, oleomargarine, lard substitutes, glycerin, lubricants, and cosmetics.
Cottonseed oil has been used as a tablet binder for acetaminophen; for characterization of the hot-melt fluid bed coating process;(1) in the manufacturing of stable oral pharmaceutical powders; in encapsulation of enzymes; and as an aqueous dispersion in pharmaceutical coating.

Safety Profile

Questionable carcinogen with experimental tumorigenic data. Experimental teratogenic effects. An allergen. Combustible liquid when exposed to heat or flame. However, if allowed to impregnate rags or oily waste, it can become a dangerous hazard due to spontaneous heating. To fight fire, use COa, dry chemical.

Safety

Cottonseed oil emulsions have in the past been used in long-term intravenous nutrition regimens. A complex of adverse reactions,called the ‘overloading syndrome’has been seen with chronic administration of cottonseed oil emulsion. This consisted of anorexia,nausea,abdominal pain,headache,fever,and sorethroat. Signs of impaired liver function, anemia, hepatosplenomegaly, thrombocytopenia, and spontaneous hemorrhage due to delayed blood clotting have been reported. For parenteral nutrition purposes, cottonseed oil has been replaced by soybean oil,especially in pregnant women, where the use of cottonseed lipid emulsion has been associated with adverse effects.
A notable difference between the cottonseed oil emulsion and the soybean oil emulsion is the particle size.The cottonseed oil emulsion has much larger particles than the soybean oil emulsion. These larger particles may have been handled differently by the body, thus perhaps accounting for some of the toxic reactions.

storage

Cottonseed oil is stable if stored in a well-filled, airtight, lightresistant container in a cool, dry place. Avoid exposure to excessive heat.

Regulatory Status

Included in the FDA Inactive Ingredients Database (IM injections, oral, capsule, tablet and sublingual preparations). Included in the Canadian List of Acceptable Non-medicinal Ingredients.

COTTONSEED OIL Preparation Products And Raw materials

Global( 179)Suppliers
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
Shandong Xiya Chemical Co., Ltd 13355009207 13355009207 3007715519@qq.com China 18722 57
Sichuan Kulinan Technology Co., Ltd 400-1166-196 18981987031 cdhxsj@163.com China 11674 57
Sinopharm Chemical Reagent Co,Ltd. 86-21-63210123 sj_scrc@sinopharm.com China 9791 79
Hunan Hui Bai Shi Biotechnology Co., Ltd. 0731-85526065 13308475853 ivy@hnhbsj.com China 7236 62
Maya High Purity Chemicals +86 (573) 82222445 (0)18006601000 452520369 sales@maya-r.com China 11693 57
Spectrum Chemical Manufacturing Corp. 021-021-021-67601398-809-809-809 15221380277 marketing_china@spectrumchemical.com China 9643 60
Thermo Fisher Scientific 800-810-5118 cnchemical@thermofisher.com China 17752 75
9ding chemical ( Shanghai) Limited 4009209199 sales@9dingchem.com China 22497 55

View Lastest Price from COTTONSEED OIL manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Cottonseed oil pictures 2026-09-11 Cottonseed oil
8001-29-4
$1.00 1KG 99% 100kg/month WUHAN FORTUNA CHEMICAL CO., LTD
COTTONSEED OIL pictures 2026-06-30 COTTONSEED OIL
8001-29-4
1kg 99% 10000KGS Shaanxi Dideu New Materials Co. Ltd
Cottonseed oil pictures 2026-05-08 Cottonseed oil
8001-29-4
≥98% 10g TargetMol Chemicals Inc.
LIPEX 109 COTTONSEED OIL cottonseed oil from cottonseed OIL OF COTTON SEED cottondoil cottonoil Cottonseedacidulatedsoapstock cottonseedoilacid deodorizedwinterizedcottonseedoil nci-c50168 Primebleachablesummeryellowcottonseedoil Solventextractedcrudecottonseedoil GOSSYPIUM HERBACEUM (COTTON) SEED OIL Cottonseed Oil (1 g) COTTONSEED OIL REFINED Cottonseed oil,unhydrogenated Cottonseed Oil (1 g) (AS) Gossypium hirsutum seed oil Gossypium hirsutum, seed oils Oils, cottonseed COTTONSEED OIL, 1000MG, NEAT Cottonseed oil, pure COTTONSEEDOIL,NF Baumwoellsamenoel COTTONSEED OIL USP/EP/BP COTTONSEED OIL USP/BP/EP Cottonseed oil, equivalent to analytical standard Baumwollsamenoel Refined Cottonseed Oils Cottonseed oil, 10 mM in DMSO cotton 8001-29-4 Oils Lipids Biochemicals and Reagents BioChemical Biochemicals and Reagents Lipids Oils CO - CZFood&Beverage Standards Natural Derived FatsBiochemicals and Reagents Alphabetic C FA/FAME/Lipids/Steroids Lipid Analytical Standards LipidsFood&Beverage Standards OilsOther Lipid Related Products