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MURISTERONE A

MURISTERONE A Structure
MURISTERONE A structure
CAS No.
38778-30-2
Chemical Name:
MURISTERONE A
Synonyms
MURA;Muristerone;MURISTERONE A;Ecdysonic sterol;MURISTERONE A(P);MURISTERONE A USP/EP/BP;MURISTERONE A, IPOMOEA SPP;Muristerone A, EcR agonist;5B, 7-CHOLESTENE-2B,3B,5A,11A,14,20,22-HEPTOL-6-ONE;2B,3B,5A,11A,14,20,22-HEPTAHYDROXY-5B-7-CHOLESTEN-6-ONE
CBNumber:
CB3781616
Molecular Formula:
C27H44O8
Molecular Weight:
496.63
MDL Number:
MFCD00056450
MOL File:
38778-30-2.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-11 16:31:51
Product description Number Pack Size Price
Muristerone A ≥95% 11741 250μg $63
Muristerone A ≥95% 11741 1mg $171
Muristerone A ≥95% 11741 250μg $57
Muristerone A ≥95% 11741 1mg $155
Muristerone A Asreported 284116 1mg $472
Request For Quotation

MURISTERONE A Properties

Boiling point 707.2±60.0 °C(Predicted)
Density 1.33±0.1 g/cm3(Predicted)
storage temp. −20°C
solubility Soluble in DMSO
form solid
pka 11.78±0.70(Predicted)
color white

SAFETY

Risk and Safety Statements

WGK Germany  3

MURISTERONE A price More Price(42)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 11741 Muristerone A ≥95% 38778-30-2 250μg $63 2026-04-30 Buy
Cayman Chemical 11741 Muristerone A ≥95% 38778-30-2 1mg $171 2026-04-30 Buy
Cayman Chemical 11741 Muristerone A ≥95% 38778-30-2 250μg $57 2024-03-01 Buy
Cayman Chemical 11741 Muristerone A ≥95% 38778-30-2 1mg $155 2024-03-01 Buy
Usbiological 284116 Muristerone A Asreported 38778-30-2 1mg $472 2026-06-03 Buy
Product number Packaging Price Buy
11741 250μg $63 Buy
11741 1mg $171 Buy
11741 250μg $57 Buy
11741 1mg $155 Buy
284116 1mg $472 Buy

MURISTERONE A Chemical Properties,Uses,Production

Description

Muristerone A is a natural analog of 20-hydroxyecdysone . It is an agonist of the ecdysteroid receptor (Kd = 1 nM), a nuclear receptor that heterodimerizes with a retinoid X receptor ortholog and regulates arthropod development. Muristerone A is used as an agonist in ecdysone-inducible gene expression systems in mammalian cells. However, it inhibits apoptosis in the human colon carcinoma cell line RKO by inducing the upregulation of Bcl-xL, suggesting limitations in its use in certain types of studies.

Uses

Muristerone A, an ecdysteroid, is widely used for the induction of ecdysteroid-dependent transcription in mammalian cells.

Biological Activity

Ecdysone analog that acts as an inducer of ecdysone-inducible gene expression systems in mammalian cells and transgenic animals. Stimulates Bcl-XL mRNA transcription and inhibits TRAIL- and hFasL-induced apoptosis in RKO cells.

storage

+4°C

References

[1] A C ZELHOF. Identification and characterization of a Drosophila nuclear receptor with the ability to inhibit the ecdysone response.[J]. Proceedings of the National Academy of Sciences of the United States of America, 1995, 92 23: 10477-10481. DOI: 10.1073/pnas.92.23.10477
[2] T M LANDON. Characterization and partial purification of the Drosophila Kc cell ecdysteroid receptor.[J]. The Journal of Biological Chemistry, 1988, 263 10: 4693-4697.
[3] MARKUS LEZZI. Ligand-induced heterodimerization between the ligand binding domains of the Drosophila ecdysteroid receptor and ultraspiracle[J]. The FEBS journal, 2009, 269 13: 3237-3245. DOI: 10.1046/j.1432-1033.2002.03001.x
[4] D NO  R M E  T P Yao. Ecdysone-inducible gene expression in mammalian cells and transgenic mice.[J]. Proceedings of the National Academy of Sciences of the United States of America, 1996, 93 8: 3346-3351. DOI: 10.1073/pnas.93.8.3346
[5] E SAEZ. Identification of ligands and coligands for the ecdysone-regulated gene switch.[J]. Proceedings of the National Academy of Sciences of the United States of America, 2000, 97 26: 14512-14517. DOI: 10.1073/pnas.260499497
[6] I OEHME  M Z  S Bsser. Agonists of an ecdysone-inducible mammalian expression system inhibit Fas Ligand- and TRAIL-induced apoptosis in the human colon carcinoma cell line RKO[J]. Cell Death and Differentiation, 2005, 13 2: 189-201. DOI: 10.1038/sj.cdd.4401730

MURISTERONE A Preparation Products And Raw materials

Raw materials

Preparation Products

MURISTERONE A Suppliers

Global( 89)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354; +17819995354 marketing@targetmol.com United States 32466 58
Dideu Industries Group Limited 		+86-86-15536356810 +8617392712697 1022@dideu.com China 29095 58
Hangzhou MolCore BioPharmatech Co.,Ltd. 		+86-057181025280; +8617767106207 sales@molcore.com China 49734 58
R&D Scientific Inc. 		+1-2266000236 sales@rdscientific.com Canada 1941 58
Aladdin Scientific 		tp@aladdinsci.com United States 52923 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
3B Pharmachem (Wuhan) International Co.,Ltd. 18930552037 3bsc@sina.com China 15838 69
Chemsky（shanghai）International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32321 50
BOC Sciences 1-631-485-4226; 16314854226 info@bocsci.com United States 9920 65
Shanghai Tauto Biotech Co., Ltd. 021-51320588 tauto@tautobiotech.com China 3988 66
Supplier Advantage
TargetMol Chemicals Inc. 		58
Dideu Industries Group Limited 		58
Hangzhou MolCore BioPharmatech Co.,Ltd. 		58
R&D Scientific Inc. 		58
Aladdin Scientific 		58
J & K SCIENTIFIC LTD. 76
3B Pharmachem (Wuhan) International Co.,Ltd. 69
Chemsky（shanghai）International Co.,Ltd. 50
BOC Sciences 65
Shanghai Tauto Biotech Co., Ltd. 66

View Lastest Price from MURISTERONE A manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Muristerone A pictures 2026-05-11 Muristerone A
38778-30-2
 $388.00 10g TargetMol Chemicals Inc.
Muristerone A pictures 2026-01-08 Muristerone A
38778-30-2
 $1900.00 1mg 98 5 Kg R&D Scientific Inc.

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2B,3B,5A,11A,14,20,22-HEPTAHYDROXY-5B-7-CHOLESTEN-6-ONE 2BETA,3BETA,5ALPHA,11ALPHA,14,20,22-HEPTAHYDROXY-5BETA,7-CHOLESTEN-6-ONE 2BETA,3BETA,5BETA,11ALPHA,14ALPHA,20R,22R-HEPTAHYDROXYCHOLEST-7-EN-6-ONE 5B, 7-CHOLESTENE-2B,3B,5A,11A,14,20,22-HEPTOL-6-ONE 5BETA,7-CHOLESTENE-2BETA,3BETA,5ALPHA,11ALPHA,14,20,22-HEPTOL-6-ONE MurA, 2β,3β,5β,11α,14α,20R,22R-Heptahydroxycholest-7-en-6-one (22R)-2β,3β,5,11α,14,20,22-Heptahydroxy-5β-cholest-7-en-6-one Ecdysonic sterol Muristerone Cholest-7-en-6-one, 2,3,5,11,14,20,22-heptahydroxy-, (2beta,3beta,5beta,11alpha,22R)- (2β,3β,5β,11α,22R)-2,3,5,11,14,20,22-Heptahydroxycholest-7-en-6-one MURISTERONE A(P) (2beta,3beta,5beta,11alpha,22R)-2,3,5,11,14,20,22-Heptahydroxy-cholest-7-en-6-one MURISTERONE A MURISTERONE A, IPOMOEA SPP MURA 2β,3β,5β,11α,14α,20R,22R-Heptahydroxycholest-7-en-6-one MURISTERONE A USP/EP/BP Cholest-7-en-6-one, 2,3,5,11,14,20,22-heptahydroxy-, (2β,3β,5β,11α,22R)- Muristerone A, EcR agonist 38778-30-2 BioChemical Apoptosis and Cell Cycle Cell Biology Apoptosis Inducers Cell Signaling and Neuroscience Miscellaneous Natural Products