MRS 2279
- CAS No.
- 367909-40-8
- Chemical Name:
- MRS 2279
- Synonyms
- MRS 2279;MRS2279,MRS-2279;MRS 2279, CID: 5311301;[(1S,2R,4R)-4-[(2-chloro-6-methylaminopurin-9-yl)methyl]-2-(phosphonooxymethyl)cyclopentyl] dihydrogen phosphate;Bicyclo[3.1.0]hexane-1-methanol, 4-[2-chloro-6-(methylamino)-9H-purin-9-yl]-2-(phosphonooxy)-, 1-(dihydrogen phosphate), (1R,2S,4S,5S)-;(1R*,2S*)-4-[2-Chloro-6-(methylamino)-9H-purin-9-yl]-2-(phosphonooxy)bicyclo[3.1.0]hexane-1-methanoldihydrogenphosphateesterdiammoniumsalt
- CBNumber:
- CB3848748
- Molecular Formula:
- C13H18ClN5O8P2
- Molecular Weight:
- 469.71
- MDL Number:
- MFCD09038551
- MOL File:
- 367909-40-8.mol
- TDS File:
- TDS
MRS 2279 price More Price(6)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | FM30705 | MRS 2279 | 367909-40-8 | 1g | $2998.38 | 2026-06-04 | Buy |
| ApexBio Technology | B5265 | MRS 2279 | 367909-40-8 | 1mg | $938 | 2026-05-06 | Buy |
| Tocris | 2158 | MRS2279 ≥98%(HPLC) | 367909-40-8 | 1 | $400 | 2021-12-16 | Buy |
| TRC | M750250 | MRS2279 | 367909-40-8 | 1mg | $355 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | BRS0000600 | MRS-2279 95.00% | 367909-40-8 | 5MG | $500.42 | 2021-12-16 | Buy |
MRS 2279 Chemical Properties,Uses,Production
Uses
MRS 2279 is a selective P2Y1 antagonist with high affinity and results in modulation of aggregation of blood platelets induced by ADP.
Biological Activity
Selective, high affinity competitive antagonist of the P2Y 1 receptor (K i = 2.5 nM; IC 50 = 51.6 nM). Fails to block nucleotide signaling at most other P2Y receptors (P2Y 2 , P2Y 4 , P2Y 6 , P2Y 11 and P2Y 12 ) and potently inhibits ADP-induced aggregation of human blood platelets in vitro (pK B = 8.05).
in vivo
MRS2279 (2 μL, 1 nM; intracerebroventricular injection; 30 min prior to mechanical ventilation) reduces mouse brain injury induced by mechanical ventilation in high-pressure ventilation mice[3].
IC 50
P2Y1 Receptor: 51.6 nM (IC50)
MRS 2279 Preparation Products And Raw materials
Raw materials
Preparation Products
MRS 2279 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15813 | 69 |
| EMMX Biotechnology LLC | 888-539-0666 | info@emmx.com | United States | 8435 | 60 |
| Jinan Yaoyan Pharmaceutical Co., Ltd. | jnyaoyan@163.com | China | 3057 | 58 | |
| Nanjing Meihao Pharmaceutical Technology Co., Ltd. | meitaochem@126.com | meitaochem@126.com | China | 19087 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19935 | 58 |
| JinOu Biomedical (Nanjing) Co., Ltd. | 13000000000 | jinoupharma@163.com | China | 11706 | 58 |
| TargetMol Chemicals Inc. | 4008200310 15002144251 | marketing@tsbiochem.com | China | 24951 | 58 |
| Chengdu Peter-like Biotechnology Co., Ltd. | 028-81700200 13308200041 | 2851167782@qq.com | China | 10763 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49709 | 58 |
