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Propiverine hydrochloride

CAS No.
54556-98-8
Chemical Name:
Propiverine hydrochloride
Synonyms
PROPIVERINE HCL;Bup-4;Urecure;Noraguard;Nsc172140;Pollarine;mictonorm;Uronaverine;Mictonetten;Yansuan Bingpaiweilin
CBNumber:
CB3855472
Molecular Formula:
C23H30ClNO3
Molecular Weight:
403.94
MDL Number:
MFCD01672343
MOL File:
54556-98-8.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-16 07:06:08

Propiverine hydrochloride Properties

Melting point 224-226°C
storage temp. 2-8°C
solubility H2O: soluble5mg/mL, clear (warmed)
form powder
color white to beige
Water Solubility H2O: 5mg/mL, clear (warmed)
InChI InChI=1S/C23H29NO3.ClH/c1-3-18-26-23(19-10-6-4-7-11-19,20-12-8-5-9-13-20)22(25)27-21-14-16-24(2)17-15-21;/h4-13,21H,3,14-18H2,1-2H3;1H
InChIKey KFUJMHHNLGCTIJ-UHFFFAOYSA-N
SMILES C(OCCC)(C(=O)OC1CCN(C)CC1)(C1=CC=CC=C1)C1C=CC=CC=1.Cl
CAS DataBase Reference 54556-98-8(CAS DataBase Reference)
FDA UNII DC4GZD10H3
UNSPSC Code 12352200
NACRES NA.77

Pharmacokinetic data

Protein binding 90-95%
Excreted unchanged in urine <1%
Volume of distribution 125-473 Litres (average: 279 Litres)
Biological half-life 20 / -

SAFETY

Risk and Safety Statements

Symbol(GHS)  Corrosion (GHS05)Exclamation Mark (GHS07)
GHS05,GHS07
Signal word  Danger
Hazard statements  H315-H318-H335
Precautionary statements  P280-P302+P352-P305+P351+P338+P310
target organs Respiratory system
Hazard Codes  Xi
Risk Statements  37/38-41
Safety Statements  26-39
WGK Germany  3
RTECS  AH3297000
Storage Class 11 - Combustible Solids
Hazard Classifications Eye Dam. 1
Skin Irrit. 2
STOT SE 3
Toxicity LD50 in male, female mice, male, female rats (mg/kg): 36, 36, 22, 25 i.v.; 223, 283, 1632, 1411 s.c.; 410, 323, 1000, 1092 orally (Yamashita)
NFPA 704
0
3 0

Propiverine hydrochloride price More Price(36)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich SML0602 Propiverine hydrochloride ≥98% (HPLC) 54556-98-8 5mg $68.3 2026-04-30 Buy
Sigma-Aldrich SML0602 Propiverine hydrochloride ≥98% (HPLC) 54556-98-8 100mg $213 2026-04-30 Buy
Cayman Chemical 36049 Propiverine (hydrochloride) ≥98% 54556-98-8 25mg $44 2026-04-30 Buy
Cayman Chemical 36049 Propiverine (hydrochloride) ≥98% 54556-98-8 50mg $84 2026-04-30 Buy
Cayman Chemical 36049 Propiverine (hydrochloride) ≥98% 54556-98-8 100mg $131 2026-04-30 Buy
Product number Packaging Price Buy
SML0602 5mg $68.3 Buy
SML0602 100mg $213 Buy
36049 25mg $44 Buy
36049 50mg $84 Buy
36049 100mg $131 Buy

Propiverine hydrochloride Chemical Properties,Uses,Production

Description

Propiverine hydrochloride is a new urological agent developed for pollakuria and aconuresis. It appears to exhibit anticholinergic properties and in animal experiments inhibited KCl induced contractions in the bladder and ileum.

Chemical Properties

Off-White Solid

Originator

Apogepha (Germany)

Uses

Propiverine is used in treatment of urinary incontinence. Propiverine is an anticholinergic.

Definition

ChEBI: Propiverine hydrochloride is a diarylmethane.

brand name

Mictonorm; Mictonetten

General Description

Propiverine hydrochloride drug is a tertiary amine with spasmolytic and analgesic properties. This drug exerts neurotropic and musculotropic effects on the urinary bladder and smooth muscles. Propiverine hydrochloride has a half-life of 20 hours.

Biochem/physiol Actions

Propiverine is an antimuscarinic drug used for the treatment of overactive blaqdder and urinary incontinence. Propiverine and/or its metabolites also have calcium channel blocking properties in addition to antimuscarinic activity, which may contribute to the clinical activity.

Clinical Use


Treatment of urinary frequency, urgency and incontinence
Neurogenic bladder instability

Drug interactions

Potentially hazardous interactions with other drugs
Anti-arrhythmics: increased risk of antimuscarinic side effects with disopyramide.

Metabolism

Propiverine is extensively metabolised by intestinal and hepatic enzymes. Four metabolites were identified in urine; two of them are pharmacologically active and may contribute to the therapeutic efficacy.
Propiverine and its metabolites are excreted in the urine, bile and faeces.

Propiverine hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 194)Suppliers
Supplier Tel Email Country ProdList Advantage
Kangmei Pharmaceutical Co., Ltd. -- kangmeixg@kangmei.com.cn China 5 58
Shanghai Boyle Chemical Co., Ltd. 021-50182298 021-50180596 sales@boylechem.com China 2202 55
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Jia Xing Isenchem Co.,Ltd 0573-85285100 18627885956 isenchem@163.com China 9389 66
LGM Pharma 1-(800)-881-8210 inquiries@lgmpharma.com United States 2110 70
Chemsky(shanghai)International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32273 50
Dalian Meilun Biotech Co., Ltd. 0411-62910999 13889544652 sales@meilune.com China 4765 58
Beijing Lianben Pharm-Chemicals Tech. Co., Ltd +86-10-83386766 sales@lianben.com China 91 58
TargetMol Chemicals Inc. 021-021-33632979 15002134094 marketing@targetmol.com China 7993 58
Quality Control Solutions Ltd. 0755-66853366 13670046396 orders@qcsrm.com China 18188 56

View Lastest Price from Propiverine hydrochloride manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Propiverine hydrochloride pictures 2026-09-11 Propiverine hydrochloride
54556-98-8
$1.00 1g ≥98% 1kg/month WUHAN FORTUNA CHEMICAL CO., LTD
Propiverine hydrochloride pictures 2026-08-25 Propiverine hydrochloride
54556-98-8
1kg 0.99 1000kg Shaanxi Xianhe Biotech Co., Ltd
Propiverine hydrochloride USP/EP/BP pictures 2026-08-20 Propiverine hydrochloride USP/EP/BP
54556-98-8
$1.10 1g 99.9% 100 Tons Min Dideu Industries Group Limited

Propiverine hydrochloride Spectrum

(1-methyl-3,4,5,6-tetrahydro-2h-pyridin-4-yl) 2,2-diphenyl-2-propoxy-acetate chloride 1-methyl-4-piperidyl diphenylpropoxyacetate hydrochloride propiverine hydrochloride PROPIVERINE HYDROCHLORRIDE aceticacid,diphenylpropoxy-,1-methyl-4-piperidylester,hydrochloride alpha,alpha-diphenyl-alpha-n-propoxyaceticacid1-methylpiperidyl-4-esterhyd alpha-phenyl-alpha-propoxy-benzeneaceticaci1-methyl-4-piperidinylester alpha-phenyl-alpha-propoxybenzeneaceticacid1-methyl-4-piperidinylesterhyd diphenylpropoxyaceticacid1-methyl-4-piperidylesterhydrochloride Benzeneacetic Benzeneacetic acid, α-phenyl-α-propoxy-, 1-Methyl-4-piperidinyl ester, hydrochloride (1:1) 1-Methyl-4-piperidyldiphenylpropoxyacetateHCl 2,2-Diphenyl-2-propoxyacetic acid 1-methyl-4-piperidyl·hydrochloride Bup-4 Noraguard Urecure Uronaverine Nsc172140 Mictonetten Pollarine α-Phenyl-α-propoxybenzeneacetic Acid 1-Methyl-4-piperidinyl Ester Hydrochloride 1-Methyl-4-piperidinyl ester hydrochloride (1-Methylpiperidin-1-ium-4-yl) 2,2-diphenyl-2-propoxyacetate chloride α,α-Diphenyl-α-propoxyacetic acid hydrochloride 1-methyl-4-piperidyl ester mictonorm Propiverine Hydrochloride RS Propiverine hydrochloride USP/EP/BP Yansuan Bingpaiweilin Propiverine D7 HydrochlorideQ: What is Propiverine D7 Hydrochloride Q: What is the CAS Number of Propiverine D7 Hydrochloride Q: What is the storage condition of Propiverine D7 Hydrochloride Q: What are the applications of Propiverine D7 Hydrochloride Propiverine HydrochlorideQ: What is Propiverine Hydrochloride Q: What is the CAS Number of Propiverine Hydrochloride Q: What is the storage condition of Propiverine Hydrochloride Q: What are the applications of Propiverine Hydrochloride Propiverine hydrochloride, 10 mM in DMSO PROPIVERINE HCL 54556-98-8 C23H29NO3ClH C23H29NO3HCl Intermediates & Fine Chemicals Pharmaceuticals Aromatics Heterocycles