Nizofenone
- CAS No.
- 54533-85-6
- Chemical Name:
- Nizofenone
- Synonyms
- EkonN;Y-9179;Midafenone;Nizofenone;Nizofenone fumarate;Nizofenone USP/EP/BP;1-[2-(2-Chlorobenzoyl)-4-nitrophenyl]-2-(diethylaminomethyl)-1H-imidazole;2'-Chloro-2-[2-[(diethylamino)methyl]-1H-imidazol-1-yl]-5-nitrobenzophenone;(2-chlorophenyl)-[2-[2-(diethylaminomethyl)-1-imidazolyl]-5-nitrophenyl]methanone;(2-Chlorophenyl)[2-[2-(diethylamino)methyl]-1H-imidazol-1-y1]-5-nitmphenyl]methanone
- CBNumber:
- CB3875403
- Molecular Formula:
- C21H21ClN4O3
- Molecular Weight:
- 412.87
- MDL Number:
- MFCD00864693
- MOL File:
- 54533-85-6.mol
- MSDS File:
- SDS
| Melting point | 75-76° |
|---|---|
| Boiling point | 609.7±65.0 °C(Predicted) |
| Density | 1.28±0.1 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| pka | 8.75±0.25(Predicted) |
| FDA UNII | 7A2NOC3R88 |
| ATC code | N06BX10 |
Nizofenone Chemical Properties,Uses,Production
Description
Nizofenzone fumarate is a potent antianoxic agent reported of benefit to geriatric and stroke patients. In animal models nizofenzone is reported to have protective effects against anoxia, global ischemia or other conditions resulting from cerebral infarction. It is also claimed to be a sedative and anticonvulsant.
Chemical Properties
Pale yellow crystals from isopropyl ether, melting point 75-76°C. Nizofenone Fumarate: C21H21ClN4O3C4H4O4.[54533-86-7]. Pale yellow crystals from isopropyl ether, melting point 157-158°C. Acute toxicity LD50 male and female mice, male and female rats (mg/kg): 495, 504, 1711, 1580 orally; 62, 70, 63, 65 intravenously; 270, 278, 1830, 1629 subcutaneously.
Originator
Yoshitomi (Japan)
Uses
Nizofenone has the effect of prolonging survival time in local and global cerebral ischemia models, global cerebral ischemia-reperfusion models, and hypoxia models, and has the effect of improving brain function and shrinking cerebral embolism lesions. It is used for brain disorders caused by ischemia in the acute phase of mild to moderate subarachnoid hemorrhage.
Definition
ChEBI: Nizofenone is a member of benzophenones.
brand name
Ekonal
Nizofenone Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
Nizofenone Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| LGM Pharma | 1-(800)-881-8210 | inquiries@lgmpharma.com | United States | 2110 | 70 |
| XiaoGan ShenYuan ChemPharm co,ltd | 15527621225; 15527621225 | 1791901229@qq.com | China | 6746 | 52 |
| Chengdu HuaXia Chemical Reagent Co. Ltd | 400-1166-196 13458535857 | cdhxsj@163.com | China | 13323 | 58 |
| Shanghai Synchem Pharma Co., ltd | 21-619849051-1 18521059765 | synchempharma@aliyun.com | China | 4988 | 55 |
| Shandong Xiya Chemical Co., Ltd. | 4009903999 13395398332 | sales@xiyashiji.com | China | 20788 | 60 |
| Raw material medicin reagent co.,Ltd | sales@njromanme.com | China | 4511 | 58 | |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
| Shandong Ono Chemical Co., Ltd. | 0539-6362799 20） | China | 10007 | 58 | |
| Wuhan FengyaoTonghui Chemical Products Co., Ltd. | 027-87466105 15377573527 | 2678564200@qq.com | China | 17968 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
View Lastest Price from Nizofenone manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-20 | Nizofenone USP/EP/BP
54533-85-6
|
$1.10 | 1g | 99.9% | 100 Tons min | Dideu Industries Group Limited | |
 |
2026-05-11 | Nizofenone
54533-85-6
|
$1520.00-2500.00 | 10g | TargetMol Chemicals Inc. |
-
- Nizofenone USP/EP/BP
54533-85-6
- $1.10
- 99.9%
- Dideu Industries Group Limited
-
- Nizofenone
54533-85-6
- $1520.00-2500.00
- TargetMol Chemicals Inc.
