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KARAKOLINE

KARAKOLINE Structure
KARAKOLINE structure
CAS No.
39089-30-0
Chemical Name:
KARAKOLINE
Synonyms
Karacoline;Carmicheline(7CI);Karacoline, 10 mM in DMSO;Inhibitor,Karacoline,inhibit;(16S)-20-Ethyl-16-methoxy-4-methylaconitane-1α,8,14α-triol;(1α,14α,16β)-20-Ethyl-16-methoxy-4-methylaconitane-1,8,14-triol;Aconitane-1,8,14-triol,20-ethyl-16-methoxy-4-methyl-, (1a,14a,16b)-;Aconitane-1,8,14-triol, 20-ethyl-16-methoxy-4-methyl-, (1α,14α,16β)-;11aH-12,3,6a-Ethanylylidene-7,9-methanonaphth[2,3-b]azocine, aconitane-1,8,14-triolderiv.;(3R,6S,6aS,7R,7aR,8S,9S,10S,11aS,12S,12aR,14R)-1-Ethyl-10-methoxy-3-methyltetradecahydro-11aH-3,6a,12-(epiethane[1,1,2]triyl)-7,9-methanonaphtho[2,3-b]azocine-6,8,11a-triol
CBNumber:
CB3986952
Molecular Formula:
C22H35NO4
Molecular Weight:
377.52
MDL Number:
MFCD00274546
MOL File:
39089-30-0.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-16 07:06:08
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KARAKOLINE Properties

Melting point 185-186℃ (acetone )
Boiling point 540.2±50.0 °C(Predicted)
Density 1.30±0.1 g/cm3 (20 ºC 760 Torr)
storage temp. 2-8°C
form Solid
pka 13.80±0.70(Predicted)
color White to off-white

SAFETY

Risk and Safety Statements

RTECS  AR5569480

KARAKOLINE price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth PBA08930 Karacoline 39089-30-0 10mg $662.7 2026-06-04 Buy
Biosynth PBA08930 Karacoline 39089-30-0 25mg $1242.5 2026-06-04 Buy
Biosynth PBA08930 Karacoline 39089-30-0 50mg $1988.5 2026-06-04 Buy
ChemScene CS-0027924 Karacoline 99.58% 39089-30-0 5mg $217 2026-06-04 Buy
ChemScene CS-0027924 Karacoline 99.58% 39089-30-0 10mg $347 2026-06-04 Buy
Product number Packaging Price Buy
PBA08930 10mg $662.7 Buy
PBA08930 25mg $1242.5 Buy
PBA08930 50mg $1988.5 Buy
CS-0027924 5mg $217 Buy
CS-0027924 10mg $347 Buy

KARAKOLINE Chemical Properties,Uses,Production

Description

A second atisine base found in the tubers of Aconitum karacolicum, the structure has been elucidated from chemical and spectroscopic data. Oxidation with KMn04 gives anhydroepoxykaracoline. The alkaloid furnishes a triacetyl deriva_x0002_tive which, after pyrolysis and hydrolysis, yields acetyldemethylisopyrokaracoline.

Uses

Karacoline is an Aconitane (A189875) derivative, which is a neurotoxin which activates tetrodotoxin-sensitive Na+ channels, inducing presynaptic depolarization, thus blocking the nerve action potential which, in turn, blocks the release of neurotransmitters and decreases the end plate potential at the neuromuscular junction.

Definition

ChEBI: An organonitrogen heterocyclic compound that is aconitane bearing hydroxy groups at the 1alpha, 8, and 14alpha positions and substituted at on the nitrogen and at positions 4 and 16beta by ethyl, methyl, a d methoxy groups, respectively.

References

Sultankhodzhaev, Yunusov, Yunusov., Khim. Prir. Soedin., 9, 199 (1973)

KARAKOLINE Preparation Products And Raw materials

Raw materials

Preparation Products

KARAKOLINE Suppliers

Global( 91)Suppliers
Supplier Tel Email Country ProdList Advantage
Adamas Reagent, Ltd. 400-6009262 15618770481 yhx@titansci.com China 14098 59
Dalian Meilun Biotech Co., Ltd. 0411-62910999 13889544652 sales@meilune.com China 4765 58
Chengdu Biopurify Phytochemicals Ltd. +86-028-82633397 18982077548 cwb1@biopurify.cn China 2376 60
Shanghai Tauto Biotech Co., Ltd. 021-51320588 tauto@tautobiotech.com China 3984 66
Wuxi Zhongkun Biochemical Technology Co., Ltd. 0510-85629785 18013409632; sales@reading-chemicals.com China 15165 58
Shanghai Yongye Biotechnology Co., Ltd. 86-021-61559134 15921386130 3423497944@qq.com China 8135 55
ALB Technology Limited 702-983-3769 sales@albtechnology.com United States 2992 55
Wuhan ChemFaces Biochemical Co., Ltd. 18607101326 15172504745 aileen@chemfaces.com China 6904 55
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
Shanghai QianYan Bio-technology Co., Ltd 02781293128 orders@biochemsafebuy.com China 9904 55
Supplier Advantage
Adamas Reagent, Ltd. 59
Dalian Meilun Biotech Co., Ltd. 58
Chengdu Biopurify Phytochemicals Ltd. 60
Shanghai Tauto Biotech Co., Ltd. 66
Wuxi Zhongkun Biochemical Technology Co., Ltd. 58
Shanghai Yongye Biotechnology Co., Ltd. 55
ALB Technology Limited 55
Wuhan ChemFaces Biochemical Co., Ltd. 55
Shanghai YuanYe Biotechnology Co., Ltd. 60
Shanghai QianYan Bio-technology Co., Ltd 55

View Lastest Price from KARAKOLINE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Karacoline pictures 2026-07-15 Karacoline
39089-30-0
 $64.00-263.00 99.64% 10g TargetMol Chemicals Inc.
  • Karacoline pictures
  • Karacoline
    39089-30-0
  • $64.00-263.00
  • 99.64%
  • TargetMol Chemicals Inc.

KARAKOLINE Spectrum

KARAKOLINE(39089-30-0)1HNMR

39089-30-0(KARAKOLINE)Related Search:

Hypaconine ranaconitine Aconitane-1,8,14,15-tetrol, 20-ethyl-6,16-dimethoxy-4-(methoxymethyl)- , (1alpha,6alpha,14alpha,15alpha,16beta)- INDACONITINE Aconitine
benzoylmesaconine CRASSICAULINE A Acetylaconitine Benzoylhypacoitine 12-epi-Napelline
benzoylaconine Mesaconitine Hypaconitine VILMORRIANINE C Bullatine B
CHASMANINE KARAKOLINE VILMORRIANINE A

1of4

(16S)-20-Ethyl-16-methoxy-4-methylaconitane-1α,8,14α-triol Aconitane-1,8,14-triol,20-ethyl-16-methoxy-4-methyl-, (1a,14a,16b)- Aconitane-1,8,14-triol, 20-ethyl-16-methoxy-4-methyl-, (1α,14α,16β)- Carmicheline(7CI) 11aH-12,3,6a-Ethanylylidene-7,9-methanonaphth[2,3-b]azocine, aconitane-1,8,14-triolderiv. (1α,14α,16β)-20-Ethyl-16-methoxy-4-methylaconitane-1,8,14-triol Inhibitor,Karacoline,inhibit Karacoline, 10 mM in DMSO (3R,6S,6aS,7R,7aR,8S,9S,10S,11aS,12S,12aR,14R)-1-Ethyl-10-methoxy-3-methyltetradecahydro-11aH-3,6a,12-(epiethane[1,1,2]triyl)-7,9-methanonaphtho[2,3-b]azocine-6,8,11a-triol Karacoline 39089-30-0 Alkaloids chemical reagent pharmaceutical intermediate phytochemical reference standards from Chinese medicinal herbs (TCM). standardized herbal extract