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KARAKOLINE

KARAKOLINE structure

CAS No.: 39089-30-0

Chemical Name:: KARAKOLINE

Synonyms: Karacoline;Carmicheline(7CI);Karacoline, 10 mM in DMSO;Inhibitor,Karacoline,inhibit;(16S)-20-Ethyl-16-methoxy-4-methylaconitane-1α,8,14α-triol;(1α,14α,16β)-20-Ethyl-16-methoxy-4-methylaconitane-1,8,14-triol;Aconitane-1,8,14-triol,20-ethyl-16-methoxy-4-methyl-, (1a,14a,16b)-;Aconitane-1,8,14-triol, 20-ethyl-16-methoxy-4-methyl-, (1α,14α,16β)-;11aH-12,3,6a-Ethanylylidene-7,9-methanonaphth[2,3-b]azocine, aconitane-1,8,14-triolderiv.;(3R,6S,6aS,7R,7aR,8S,9S,10S,11aS,12S,12aR,14R)-1-Ethyl-10-methoxy-3-methyltetradecahydro-11aH-3,6a,12-(epiethane[1,1,2]triyl)-7,9-methanonaphtho[2,3-b]azocine-6,8,11a-triol

CBNumber:: CB3986952

Molecular Formula:: C22H35NO4

Molecular Weight:: 377.52

MDL Number:: MFCD00274546

MOL File:: 39089-30-0.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-07-16 07:06:08

Product description	Number	Pack Size	Price
Karacoline	PBA08930	10mg	$662.7
Karacoline	PBA08930	25mg	$1242.5
Karacoline	PBA08930	50mg	$1988.5
Karacoline 99.58%	CS-0027924	5mg	$217
Karacoline 99.58%	CS-0027924	10mg	$347
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KARAKOLINE Properties

Melting point	185-186℃ (acetone )
Boiling point	540.2±50.0 °C(Predicted)
Density	1.30±0.1 g/cm3 (20 ºC 760 Torr)
storage temp.	2-8°C
form	Solid
pka	13.80±0.70(Predicted)
color	White to off-white

SAFETY

Risk and Safety Statements

RTECS	AR5569480

KARAKOLINE price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Biosynth	PBA08930	Karacoline	39089-30-0	10mg	$662.7	2026-06-04	Buy
Biosynth	PBA08930	Karacoline	39089-30-0	25mg	$1242.5	2026-06-04	Buy
Biosynth	PBA08930	Karacoline	39089-30-0	50mg	$1988.5	2026-06-04	Buy
ChemScene	CS-0027924	Karacoline 99.58%	39089-30-0	5mg	$217	2026-06-04	Buy
ChemScene	CS-0027924	Karacoline 99.58%	39089-30-0	10mg	$347	2026-06-04	Buy

Product number	Packaging	Price	Buy
PBA08930	10mg	$662.7	Buy
PBA08930	25mg	$1242.5	Buy
PBA08930	50mg	$1988.5	Buy
CS-0027924	5mg	$217	Buy
CS-0027924	10mg	$347	Buy

KARAKOLINE Chemical Properties,Uses,Production

Description

A second atisine base found in the tubers of Aconitum karacolicum, the structure has been elucidated from chemical and spectroscopic data. Oxidation with KMn04 gives anhydroepoxykaracoline. The alkaloid furnishes a triacetyl deriva_x0002_tive which, after pyrolysis and hydrolysis, yields acetyldemethylisopyrokaracoline.

Uses

Karacoline is an Aconitane (A189875) derivative, which is a neurotoxin which activates tetrodotoxin-sensitive Na+ channels, inducing presynaptic depolarization, thus blocking the nerve action potential which, in turn, blocks the release of neurotransmitters and decreases the end plate potential at the neuromuscular junction.

Definition

ChEBI: An organonitrogen heterocyclic compound that is aconitane bearing hydroxy groups at the 1alpha, 8, and 14alpha positions and substituted at on the nitrogen and at positions 4 and 16beta by ethyl, methyl, a d methoxy groups, respectively.

References

Sultankhodzhaev, Yunusov, Yunusov., Khim. Prir. Soedin., 9, 199 (1973)

KARAKOLINE Preparation Products And Raw materials

Raw materials

Preparation Products

KARAKOLINE Suppliers

Global( 92)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Chengdu GLP biotechnology Co Ltd	028-87075086 13350802083	scglp@glp-china.com	CHINA	1824	58
Chengdu Biopurify Phytochemicals Ltd.	+86-28-82633860; +8618080483897	sales@biopurify.com	China	4616	58
Wuhan ChemNorm Biotech Co.,Ltd.	+86-27-8439 4403 18971486879	sales@chemnorm.com	CHINA	2935	58
TargetMol Chemicals Inc.	+1-781-999-5354; +17819995354	marketing@targetmol.com	United States	32466	58
Hubei Ipure Biology Co., Ltd	+8613367258412	ada@ipurechemical.com	China	10236	58
BOC Sciences	16314854226; +16314854226	inquiry@bocsci.com	United States	19853	58
Chengdu Youngshe Chemical Co., Ltd.	+8618108235634	Cecilia@youngshechem.com	China	2345	58
TargetMol Chemicals Inc.	+1-781-999-5354;	support@targetmol.com	United States	39037	58
ShenZhen Trendseen Biological Technology Co.,Ltd.	13417589054	trendseenbio@gmail.com	China	11680	58
Aladdin Scientific		tp@aladdinsci.com	United States	52923	58

Supplier	Advantage
Chengdu GLP biotechnology Co Ltd	58
Chengdu Biopurify Phytochemicals Ltd.	58
Wuhan ChemNorm Biotech Co.,Ltd.	58
TargetMol Chemicals Inc.	58
Hubei Ipure Biology Co., Ltd	58
BOC Sciences	58
Chengdu Youngshe Chemical Co., Ltd.	58
TargetMol Chemicals Inc.	58
ShenZhen Trendseen Biological Technology Co.,Ltd.	58
Aladdin Scientific	58

View Lastest Price from KARAKOLINE manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2026-07-15	Karacoline 39089-30-0	$64.00-263.00		99.64%	10g	TargetMol Chemicals Inc.

Karacoline
39089-30-0
$64.00-263.00
99.64%
TargetMol Chemicals Inc.

KARAKOLINE Spectrum

KARAKOLINE(39089-30-0)¹HNMR

39089-30-0(KARAKOLINE)Related Search:

Hypaconine ranaconitine Aconitane-1,8,14,15-tetrol, 20-ethyl-6,16-dimethoxy-4-(methoxymethyl)- , (1alpha,6alpha,14alpha,15alpha,16beta)- INDACONITINE Aconitine

benzoylmesaconine CRASSICAULINE A Acetylaconitine Benzoylhypacoitine 12-epi-Napelline

benzoylaconine Mesaconitine Hypaconitine VILMORRIANINE C Bullatine B

CHASMANINE KARAKOLINE VILMORRIANINE A

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(16S)-20-Ethyl-16-methoxy-4-methylaconitane-1α,8,14α-triol Aconitane-1,8,14-triol,20-ethyl-16-methoxy-4-methyl-, (1a,14a,16b)- Aconitane-1,8,14-triol, 20-ethyl-16-methoxy-4-methyl-, (1α,14α,16β)- Carmicheline(7CI) 11aH-12,3,6a-Ethanylylidene-7,9-methanonaphth[2,3-b]azocine, aconitane-1,8,14-triolderiv. (1α,14α,16β)-20-Ethyl-16-methoxy-4-methylaconitane-1,8,14-triol Inhibitor,Karacoline,inhibit Karacoline, 10 mM in DMSO (3R,6S,6aS,7R,7aR,8S,9S,10S,11aS,12S,12aR,14R)-1-Ethyl-10-methoxy-3-methyltetradecahydro-11aH-3,6a,12-(epiethane[1,1,2]triyl)-7,9-methanonaphtho[2,3-b]azocine-6,8,11a-triol Karacoline 39089-30-0 Alkaloids chemical reagent pharmaceutical intermediate phytochemical reference standards from Chinese medicinal herbs (TCM). standardized herbal extract