ChemicalBook >> CAS DataBase List >>1H-Isoindole-1,3(2H)-dione, 5-(3-aminopropyl)-2-(2,6-dioxo-3-piperidinyl)-, hydrochloride (1:1)

1H-Isoindole-1,3(2H)-dione, 5-(3-aminopropyl)-2-(2,6-dioxo-3-piperidinyl)-, hydrochloride (1:1)

1H-Isoindole-1,3(2H)-dione, 5-(3-aminopropyl)-2-(2,6-dioxo-3-piperidinyl)-, hydrochloride (1:1) structure

CAS No.: 2357110-84-8

Chemical Name:: 1H-Isoindole-1,3(2H)-dione, 5-(3-aminopropyl)-2-(2,6-dioxo-3-piperidinyl)-, hydrochloride (1:1)

Synonyms: Thalidomide-4-C3-NH2, HCl salt;Thalidomide-4-C3-NH2 hydrochloride;Thalidomide-4-C3-NH2 hydrochloride?, Thalidomide-4-C3-NH2 HCl;5-(3-Aminopropyl)-2-(2,6-dioxo-3-piperidyl)isoindoline-1,3-dione Hydrochloride;1H-Isoindole-1,3(2H)-dione, 5-(3-aminopropyl)-2-(2,6-dioxo-3-piperidinyl)-, hydrochloride (1:1)

CBNumber:: CB410339604

Molecular Formula:: C16H18ClN3O4

Molecular Weight:: 351.79

MDL Number:

MOL File:: 2357110-84-8.mol

Last updated:2025-04-18 09:52:14

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1H-Isoindole-1,3(2H)-dione, 5-(3-aminopropyl)-2-(2,6-dioxo-3-piperidinyl)-, hydrochloride (1:1) price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
BroadPharm	bp-40595	Thalidomide-4-C3-NH2, HCl salt	2357110-84-8	50MG	$430	2026-05-24	Buy
BroadPharm	bp-40595	Thalidomide-4-C3-NH2, HCl salt	2357110-84-8	100MG	$650	2026-05-24	Buy
BroadPharm	bp-40595	Thalidomide-4-C3-NH2, HCl salt	2357110-84-8	250MG	$1250	2026-05-24	Buy
aablocks	AA028W0V	5-(3-aminopropyl)-2-(2,6-dioxopiperidin-3-yl)-2,3-dihydro-1H-isoindole-1,3-dione hydrochloride 95.00%	2357110-84-8	50mg	$423	2026-06-02	Buy
aablocks	AA028W0V	5-(3-aminopropyl)-2-(2,6-dioxopiperidin-3-yl)-2,3-dihydro-1H-isoindole-1,3-dione hydrochloride 95.00%	2357110-84-8	100mg	$612	2026-06-02	Buy

Product number	Packaging	Price	Buy
bp-40595	50MG	$430	Buy
bp-40595	100MG	$650	Buy
bp-40595	250MG	$1250	Buy
AA028W0V	50mg	$423	Buy
AA028W0V	100mg	$612	Buy

1H-Isoindole-1,3(2H)-dione, 5-(3-aminopropyl)-2-(2,6-dioxo-3-piperidinyl)-, hydrochloride (1:1) Chemical Properties, Uses, Production

Uses

Thalidomide-4-C3-NH2 hydrochloride is the Thalidomide-based cereblon ligand used in the recruitment of CRBN protein. Thalidomide-4-C3-NH2 hydrochloride can be connected to the ligand for protein by a linker to form PROTACs[1].

IC 50

Cereblon

References

[1] Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-994. DOI:10.1016/j.stem.2020.07.019

1H-Isoindole-1,3(2H)-dione, 5-(3-aminopropyl)-2-(2,6-dioxo-3-piperidinyl)-, hydrochloride (1:1) Preparation Products And Raw materials

Raw materials

Preparation Products

1H-Isoindole-1,3(2H)-dione, 5-(3-aminopropyl)-2-(2,6-dioxo-3-piperidinyl)-, hydrochloride (1:1) Suppliers

Global Suppliers ( 5)

Supplier	Tel	Email	Country	ProdList	Advantage
Jilin Province Woda Biotechnology Co., Ltd.	13504435624	1927928688@qq.com	China	1644	58
Shaoyuan Technology (Shanghai) Co., Ltd.	021-50795510 4000665055	marketing@accelachem.com	China	9831	58
Jilin Chinese Academy of Sciences-yanshen Technology	18143011203	ET-market@chemextension.com	China	38923	58
Shandong Dayou Pharmaceutical Research and Development Co., Ltd.	hanfangpharma@126.com 15165037910	hanfangpharma@126.com	China	25800	58
Henan Mengtai Pharmaceutical Technology Co., Ltd	17634413542	1959525201@qq.com	China	9011	58

Supplier	Advantage
Jilin Province Woda Biotechnology Co., Ltd.	58
Shaoyuan Technology (Shanghai) Co., Ltd.	58
Jilin Chinese Academy of Sciences-yanshen Technology	58
Shandong Dayou Pharmaceutical Research and Development Co., Ltd.	58
Henan Mengtai Pharmaceutical Technology Co., Ltd	58

2357110-84-8 (1H-Isoindole-1,3(2H)-dione, 5-(3-aminopropyl)-2-(2,6-dioxo-3-piperidinyl)-, hydrochloride (1:1)) Related Search:

Carbamic acid, N-[2-[2-[2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]ethoxy]ethoxy]ethyl]-, 1,1-dimethylethyl ester Propanoic acid, 3-[2-[2-[2-[2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]ethoxy]ethoxy]ethoxy]ethoxy]- 4-[(4-Aminobutyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl Propanoic acid, 3-[2-[2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]ethoxy]ethoxy]-, 2,5-dioxo-1-pyrrolidinyl ester Thalidomide-O-C6-acid

Thalidomide-4-O-C8-NH2 Thalidomide-O-C3-acid 5,6-dichloro-2-(2,6-dioxopiperidin-3-yl)-2,3-dihydro-1H-isoindole-1,3-dione Thalidomide-4-O-C6-NH2 hydrochloride Carbamic acid, N-[6-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]hexyl]-, 1,1-dimethylethyl ester

Nonanoic acid, 9-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]-, 1,1-dimethylethyl ester Thalidomide-O-C5-acid N-(3-(2-(2-(3-Aminopropoxy)ethoxy)ethoxy)propyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide Trifluoroacetate 6-Bromo-N-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)hexanamide

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1H-Isoindole-1,3(2H)-dione, 5-(3-aminopropyl)-2-(2,6-dioxo-3-piperidinyl)-, hydrochloride (1:1) Thalidomide-4-C3-NH2 hydrochloride Thalidomide-4-C3-NH2, HCl salt Thalidomide-4-C3-NH2 hydrochloride?, Thalidomide-4-C3-NH2 HCl 5-(3-Aminopropyl)-2-(2,6-dioxo-3-piperidyl)isoindoline-1,3-dione Hydrochloride 2357110-84-8