ChemicalBook >> CAS DataBase List >>5,8,11,14-Eicosatetraenamide, N-[(1R)-2-hydroxy-1-methylethyl]-13-methyl-, (5Z,8Z,11Z,13S,14Z)-

5,8,11,14-Eicosatetraenamide, N-[(1R)-2-hydroxy-1-methylethyl]-13-methyl-, (5Z,8Z,11Z,13S,14Z)-

5,8,11,14-Eicosatetraenamide, N-[(1R)-2-hydroxy-1-methylethyl]-13-methyl-, (5Z,8Z,11Z,13S,14Z)- structure

CAS No.: 2244425-65-6

Chemical Name:: 5,8,11,14-Eicosatetraenamide, N-[(1R)-2-hydroxy-1-methylethyl]-13-methyl-, (5Z,8Z,11Z,13S,14Z)-

Synonyms: AMG-315;5,8,11,14-Eicosatetraenamide, N-[(1R)-2-hydroxy-1-methylethyl]-13-methyl-, (5Z,8Z,11Z,13S,14Z)-

CBNumber:: CB410801280

Molecular Formula:: C24H41NO2

Molecular Weight:: 375.59

MDL Number:

MOL File:: 2244425-65-6.mol

MSDS File:: SDS

Last updated:2023-03-31 09:12:58

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5,8,11,14-Eicosatetraenamide, N-[(1R)-2-hydroxy-1-methylethyl]-13-methyl-, (5Z,8Z,11Z,13S,14Z)- Properties

Boiling point	536.0±50.0 °C(Predicted)
Density	0.931±0.06 g/cm3(Predicted)
pka	14.51±0.10(Predicted)

5,8,11,14-Eicosatetraenamide, N-[(1R)-2-hydroxy-1-methylethyl]-13-methyl-, (5Z,8Z,11Z,13S,14Z)- Chemical Properties, Uses, Production

Description

AMG-315 is a Potent Endocannabinoid Ligand with Stability to Metabolizing Enzymes. AMG-315 is a chiral arachidonoyl ethanolamide (AEA) analogue or (13S,1′R)-dimethylanandamide. AMG-315 is a high affinity ligand for the CB1 receptor (Ki of 7.8 ± 1.4 nM) that behaves as a potent CB1 agonist in vitro (EC50 = 0.6 ± 0.2 nM). AMG-315 is the first potent AEA analogue with significant stability for all endocannabinoid hydrolyzing enzymes as well as the oxidative enzymes COX-2. AMG-315 will serve as a very useful endocannabinoid probe.

5,8,11,14-Eicosatetraenamide, N-[(1R)-2-hydroxy-1-methylethyl]-13-methyl-, (5Z,8Z,11Z,13S,14Z)- Preparation Products And Raw materials

Raw materials

Preparation Products

5,8,11,14-Eicosatetraenamide, N-[(1R)-2-hydroxy-1-methylethyl]-13-methyl-, (5Z,8Z,11Z,13S,14Z)- Suppliers

Global Suppliers ( 1)

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	15002134094	marketing@targetmol.cn	China	29874	58

Supplier	Advantage
TargetMol Chemicals Inc.	58

AMG-315 5,8,11,14-Eicosatetraenamide, N-[(1R)-2-hydroxy-1-methylethyl]-13-methyl-, (5Z,8Z,11Z,13S,14Z)- 2244425-65-6