4,5,6,7-tetrahydro-1H-benzoimidazole
- CAS No.
- 3752-24-7
- Chemical Name:
- 4,5,6,7-tetrahydro-1H-benzoimidazole
- Synonyms
- 4,5,6,7-Tetrahydrobenzimidazole;4,5,6,7-TETRAHYDRO-1H-BENZIMIDAZOLE;1H-Benzimidazole, 4,5,6,7-tetrahydro-;4,5,6,7-tetrahydro-1H-benzenebenzoimidazole
- CBNumber:
- CB41261208
- Molecular Formula:
- C7H10N2
- Molecular Weight:
- 122.17
- MDL Number:
- MFCD00829762
- MOL File:
- 3752-24-7.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 4,5,6,7-Tetrahydro-1H-benzoimidazole 98% | OR912584 | 1g | $21 |
| 4,5,6,7-Tetrahydro-1H-benzoimidazole 98% | OR912584 | 5g | $97 |
| 4,5,6,7-Tetrahydro-1H-benzoimidazole 98% | OR912584 | 25g | $475 |
| 4,5,6,7-Tetrahydro-1H-benzoimidazole 98% | OR912584 | 100g | $1566 |
| 4,5,6,7-Tetrahydro-1H-benzoimidazole 98% | AS15253 | 1g | $36 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H332-H335 |
| Precautionary statements | P261-P280-P305+P351+P338 |
| HS Code | 2933998090 |
4,5,6,7-tetrahydro-1H-benzoimidazole price More Price(35)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | OR912584 | 4,5,6,7-Tetrahydro-1H-benzoimidazole 98% | 3752-24-7 | 1g | $21 | 2026-06-04 | Buy |
| Apolloscientific | OR912584 | 4,5,6,7-Tetrahydro-1H-benzoimidazole 98% | 3752-24-7 | 5g | $97 | 2026-06-04 | Buy |
| Apolloscientific | OR912584 | 4,5,6,7-Tetrahydro-1H-benzoimidazole 98% | 3752-24-7 | 25g | $475 | 2026-06-04 | Buy |
| Apolloscientific | OR912584 | 4,5,6,7-Tetrahydro-1H-benzoimidazole 98% | 3752-24-7 | 100g | $1566 | 2026-06-04 | Buy |
| Activate Scientific | AS15253 | 4,5,6,7-Tetrahydro-1H-benzoimidazole 98% | 3752-24-7 | 1g | $36 | 2026-06-04 | Buy |
4,5,6,7-tetrahydro-1H-benzoimidazole Chemical Properties,Uses,Production
Uses
4,5-Tetramethyleneimidazole is a useful reactant for preparation of imidazolylnitroquinoxalinedione.
Synthesis Reference(s)
The Journal of Organic Chemistry, 41, p. 19, 1976 DOI: 10.1021/jo00863a004
Synthesis
51-17-2
3752-24-7
The general procedure for the synthesis of 4,5,6,7-tetrahydro-1H-benzimidazole from benzimidazole was as follows: a suspension of benzimidazole (3.0 g, 25.4 mmol) with Pd/C (Degussa 5 wt%; 1.3 g) in acetic acid (50 mL) was added to a Parr reactor, and the reaction was carried out at 80 °C and 200 psi hydrogen pressure overnight. Upon completion of the reaction, the mixture was cooled to room temperature, filtered through diatomaceous earth and the diatomaceous earth pad was washed several times with distilled water. The filtrates were combined and the pH was adjusted to 9 with solid K2CO3, followed by liquid-liquid separation by addition of ethyl acetate. The organic layer was dried over anhydrous magnesium sulfate and concentrated under reduced pressure to give 4,5,6,7-tetrahydro-1H-benzimidazole (2.4 g, 77% yield) as a white solid. The product was characterized by 1H NMR (400 MHz, CDCl3): δ 1.82-1.85 (m, 4H), 2.06-2.10 (m, 4H), 7.55 (s, 1H), 10.21 (br s, NH).LC-MS (ES+) analysis showed m/z 123 ([M+H]+) and retention time (RT) was consistent with the solvent front (method A).
References
[1] Organic Letters, 2004, vol. 6, # 5, p. 735 - 738
[2] Patent: WO2015/86513, 2015, A1. Location in patent: Page/Page column 87; 88
[3] Patent: US2018/186773, 2018, A1. Location in patent: Paragraph 0793; 0794; 0795
[4] Journal fuer Praktische Chemie (Leipzig), 1958, vol. <4> 7, p. 207,212
4,5,6,7-tetrahydro-1H-benzoimidazole Preparation Products And Raw materials
4,5,6,7-tetrahydro-1H-benzoimidazole Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shaanxi Dideu Medichem Co. Ltd | +86-029-81138252 +86-173 9270 1263 | 1057@dideu.com | China | 3961 | 58 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32997 | 60 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63645 | 58 |
| Nanjing jinheyou Trading Co., Ltd. | 15705188088 | admin@jheyou.com | CHINA | 1267 | 58 |
| career henan chemical co | +86-0371-86658258 | factory@coreychem.com | China | 29780 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 +8619957148339 | market18@leapchem.com | China | 24569 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 54746 | 58 | |
| Suzhou ARTK Medchem Co., Ltd. | +86-18168183658 | sales1@artkmedchem.com | China | 39007 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
| PharmaBlock Sciences (Nanjing),Inc. | 025-86918202 4000255188 | sales@pharmablock.com | China | 5000 | 55 |
View Lastest Price from 4,5,6,7-tetrahydro-1H-benzoimidazole manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2024-07-14 | 4,5,6,7-tetrahydro-1H-benzoimidazole
3752-24-7
|
$1.00 | 1KG | 99% | 20t | Shaanxi Dideu Medichem Co. Ltd | |
 |
2020-01-10 | 4,5,6,7-tetrahydro-1H-benzoimidazole
3752-24-7
|
$1.00 | 1KG | 99% | 200kg | Career Henan Chemical Co | |
 |
2019-11-14 | 4,5,6,7-tetrahydro-1h-benzimidazole
3752-24-7
|
1g | 95%min | 20kgs/month | Nanjing jinheyou Trading Co., Ltd. |
-
- 4,5,6,7-tetrahydro-1H-benzoimidazole
3752-24-7
- $1.00
- 99%
- Shaanxi Dideu Medichem Co. Ltd
-
- 4,5,6,7-tetrahydro-1H-benzoimidazole
3752-24-7
- $1.00
- 99%
- Career Henan Chemical Co
-
- 4,5,6,7-tetrahydro-1h-benzimidazole
3752-24-7
- $0.00
- 95%min
- Nanjing jinheyou Trading Co., Ltd.
