ANKAFLAVIN
- CAS No.
- 50980-32-0
- Chemical Name:
- ANKAFLAVIN
- Synonyms
- ANKAFLAVIN;Monascus flavan;Anti-cancer Activity;Ankaflavin in Acetonitrile;2H-Furo[3,2-g][2]benzopyran-2,9(3H)-dione, 3a,4,8,9a-tetrahydro-9a-methyl-3-(1-oxooctyl)-6-(1E)-1-propen-1-yl-, (3S,3aR,9aR)-
- CBNumber:
- CB41267972
- Molecular Formula:
- C23H30O5
- Molecular Weight:
- 386.48
- MDL Number:
- MFCD32200995
- MOL File:
- 50980-32-0.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Boiling point | 590.7±50.0 °C(Predicted) |
|---|---|
| Density | 1.15±0.1 g/cm3(Predicted) |
| storage temp. | 4°C, protect from light |
| solubility | Soluble in DMSO |
| form | Solid |
| pka | 10.75±0.60(Predicted) |
| color | Light yellow to yellow |
| Major Application | (Pharmaceutical small molecule) |
| InChIKey | AQTJNEHGKRUSLT-ODTNPMSZSA-N |
| SMILES | C1(/C=C/C)OCC2C(=O)[C@]3(C)OC(=O)[C@H](C(=O)CCCCCCC)[C@@]3([H])CC=2C=1 |
| NACRES | NA.24 |
ANKAFLAVIN price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 39546 | Ankaflavin ≥98% | 50980-32-0 | 1mg | $68 | 2026-04-30 | Buy |
| Cayman Chemical | 39546 | Ankaflavin ≥98% | 50980-32-0 | 5mg | $315 | 2026-04-30 | Buy |
| Cayman Chemical | 39546 | Ankaflavin ≥98% | 50980-32-0 | 10mg | $597 | 2026-04-30 | Buy |
| Usbiological | 592510 | Ankaflavin | 50980-32-0 | 1mg | $704 | 2026-06-03 | Buy |
| Usbiological | 592510 | Ankaflavin | 50980-32-0 | 5mg | $1381 | 2026-06-03 | Buy |
ANKAFLAVIN Chemical Properties,Uses,Production
Description
Ankaflavin (AK), isolated from Monascus-Fermented red rice, is a PPARγ agonist with anti-inlfammatory activity. Ankaflavin is an active compound having anti-inflammatory, anti-cancer, antiatherosclerotic, and hypolipidemic effects.
Anti-cancer Activity
Ankaflavin was found to be toxic to human cancer cell lines Hep G2 and A549 with a similar IC50 value of 15 μg/mL, while it posed no significant toxicity to normal MRC-5 and WI-38 cells at the same concentration.Ankaflavin exhibits selective cytotoxic effect and induces cell death on cancer cells.
Description
Ankaflavin is a microbial metabolite that has been found in M. ruber and has diverse biological activities.1,2,3 It induces cytotoxicity in HepG2 hepatic carcinoma and A549 lung cancer cells (IC50 = ~15 µg/ml for both).1 Ankaflavin (15 µg/ml) induces cell cycle arrest at the G0 phase in HepG2 cells. It reduces nitric oxide (NO) production in LPS-stimulated RAW 264.7 macrophages when used at concentrations of 5, 10, and 15 µg/ml.2 Ankaflavin (10 µM) increases lipolysis in 3T3-L1 adipocytes matured by isobutylmethylxanthine (IBMX; Item No. 13347), dexamethasone (Item No. 11015), and insulin.3 In vivo, ankaflavin (5 mg/kg per day) reduces blood glucose and serum insulin levels in mice fed a high-fat diet.WARNING This product is not for human or veterinary use.
ANKAFLAVIN Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Chengdu Greenpure Biopharma CO.,Ltd | 17311681195 | zhang.liangjia@greenpurebio.com | China | 1615 | 58 |
| Chengdu Biopurify Phytochemicals Ltd. | +86-028-82633397 18982077548 | cwb1@biopurify.cn | China | 2376 | 60 |
| Shanghai Tauto Biotech Co., Ltd. | 021-51320588 | tauto@tautobiotech.com | China | 3984 | 66 |
| Wuhan ChemFaces Biochemical Co., Ltd. | 18607101326 15172504745 | aileen@chemfaces.com | China | 6904 | 55 |
| BOC Sciences | 16314854226 | info@bocsci.com | United States | 9909 | 65 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| Shandong Xiya Chemical Co., Ltd. | 4009903999 13395398332 | sales@xiyashiji.com | China | 20788 | 60 |
| Qingdao IniKem BioPharmaTech Co.,Ltd | 0532-58268781 18561687109 | sales@inikem.com | China | 298 | 55 |
| Shanghai SuperLan Chemcial Technique Centre | 0-2022843681 15618226720 | chaolaichem@foxmail.com | China | 10000 | 58 |
| Beijing Solarbio Science & Tecnology Co., Ltd. | 17801761073 18101056239 | 3193328036@qq.com | China | 28150 | 68 |
Related articles
- Ankaflavin: bioactivities, biosynthesis and applications
- Ankaflavin, derived from Monascus, has diverse bioactivities and therapeutic potential, making it valuable for addressing vari....
- Dec 1,2023
- Ankaflavin – one of secondary metabolites from Monascus-fermented products
- Ankaflavin (AK), isolated from Monascus-Fermented red rice, is a PPARγ agonist with anti-inlfammatory activity. Ankaflavin is ....
- Dec 23,2019
View Lastest Price from ANKAFLAVIN manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-27 | Ankaflavin
50980-32-0
|
$86.00-771.00 | 10g | TargetMol Chemicals Inc. | |||
 |
2026-07-27 | Ankaflavin
50980-32-0
|
$86.00-771.00 | 10g | TargetMol Chemicals Inc. | |||
 |
2025-07-19 | Ankaflavin
50980-32-0
|
10g | TargetMol Chemicals Inc. |
-
- Ankaflavin
50980-32-0
- $86.00-771.00
- TargetMol Chemicals Inc.
-
- Ankaflavin
50980-32-0
- $86.00-771.00
- TargetMol Chemicals Inc.
-
- Ankaflavin
50980-32-0
- TargetMol Chemicals Inc.
