1H-1,2,3-Triazole-4-carboxamide, 1-cyclopropyl-N-[1-[[1-(phenylmethyl)-1H-pyrazol-4-yl]methyl]-3-azetidinyl]-
![1H-1,2,3-Triazole-4-carboxamide, 1-cyclopropyl-N-[1-[[1-(phenylmethyl)-1H-pyrazol-4-yl]methyl]-3-azetidinyl]- Structure](CAS/20210305/GIF/1887193-58-9.gif)
- CAS No.
- 1887193-58-9
- Chemical Name:
- 1H-1,2,3-Triazole-4-carboxamide, 1-cyclopropyl-N-[1-[[1-(phenylmethyl)-1H-pyrazol-4-yl]methyl]-3-azetidinyl]-
- Synonyms
- EPZ032597;1H-1,2,3-Triazole-4-carboxamide, 1-cyclopropyl-N-[1-[[1-(phenylmethyl)-1H-pyrazol-4-yl]methyl]-3-azetidinyl]-
- CBNumber:
- CB412978830
- Molecular Formula:
- C20H23N7O
- Molecular Weight:
- 377.44
- MDL Number:
- MOL File:
- 1887193-58-9.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P280-P305+P351+P338 |
1H-1,2,3-Triazole-4-carboxamide, 1-cyclopropyl-N-[1-[[1-(phenylmethyl)-1H-pyrazol-4-yl]methyl]-3-azetidinyl]- price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-1225845 | EPZ032597 | 1887193-58-9 | 1mg | $700 | 2026-06-04 | Buy |
| ChemScene | CS-1225845 | EPZ032597 | 1887193-58-9 | 5mg | $1818 | 2026-06-04 | Buy |
| ChemScene | CS-1225845 | EPZ032597 | 1887193-58-9 | 10mg | $2547 | 2026-06-04 | Buy |
| aablocks | AA02E651 | 1-Cyclopropyl-N-[1-[[1-(phenylmethyl)-1H-pyrazol-4-yl]methyl]-3-azetidinyl]-1H-1,2,3-triazole-4-carboxamide | 1887193-58-9 | 1mg | $415 | 2026-06-03 | Buy |
| aablocks | AA02E651 | 1-Cyclopropyl-N-[1-[[1-(phenylmethyl)-1H-pyrazol-4-yl]methyl]-3-azetidinyl]-1H-1,2,3-triazole-4-carboxamide | 1887193-58-9 | 5mg | $1206 | 2026-06-03 | Buy |
1H-1,2,3-Triazole-4-carboxamide, 1-cyclopropyl-N-[1-[[1-(phenylmethyl)-1H-pyrazol-4-yl]methyl]-3-azetidinyl]- Chemical Properties, Uses, Production
Uses
EPZ032597 is a selective and noncompetitive SMYD2 inhibitor with an IC50 value of 16 nM. EPZ032597 is promising for research of pancreatic ductal adenocarcinoma[1][2].
References
[1] Alshammari E, et al. Mechanistic and functional extrapolation of SET and MYND domain-containing protein 2 to pancreatic cancer. World J Gastroenterol. 2022 Aug 7;28(29):3753-3766. DOI:10.3748/wjg.v28.i29.3753
[2] Thomenius MJ, et al. Small molecule inhibitors and CRISPR/Cas9 mutagenesis demonstrate that SMYD2 and SMYD3 activity are dispensable for autonomous cancer cell proliferation. PLoS One. 2018 Jun 1;13(6):e0197372. DOI:10.1371/journal.pone.0197372
1H-1,2,3-Triazole-4-carboxamide, 1-cyclopropyl-N-[1-[[1-(phenylmethyl)-1H-pyrazol-4-yl]methyl]-3-azetidinyl]- Preparation Products And Raw materials
Raw materials
Preparation Products
1H-1,2,3-Triazole-4-carboxamide, 1-cyclopropyl-N-[1-[[1-(phenylmethyl)-1H-pyrazol-4-yl]methyl]-3-azetidinyl]- Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11963 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29874 | 58 |
| Shanghai Amole Biotechnology Co., Ltd. | 13370042665 18916960931 | 2596183085@qq.com | China | 17234 | 58 |
| Supplier | Advantage |
|---|---|
| TargetMol Chemicals Inc. | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 58 |
| TargetMol Chemicals Inc. | 58 |
| Shanghai Amole Biotechnology Co., Ltd. | 58 |
