apomine
- CAS No.
- 126411-13-0
- Chemical Name:
- apomine
- Synonyms
- F-99085;apomine;SR-9223i;SR-45023A;APB-231-A2;APB-231-A-2;Apomine, 10 mM in DMSO;Tetraisopropyl 2-(3,5-di-tert-butyl-4-hydroxyphenyl)ethyl-1,1-diphosphonate;Phosphonic acid, P,P'-[2-[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]ethylidene]bis-, P,P,P',P'-tetrakis(1-methylethyl) ester
- CBNumber:
- CB41322363
- Molecular Formula:
- C28H52O7P2
- Molecular Weight:
- 562.66
- MDL Number:
- MFCD00888475
- MOL File:
- 126411-13-0.mol
- MSDS File:
- SDS
| Melting point | 102-104 °C |
|---|---|
| Boiling point | 584.5±50.0 °C(Predicted) |
| Density | 1.066±0.06 g/cm3(Predicted) |
| pka | 12.02±0.40(Predicted) |
| form | Solid |
| color | Off-white to light yellow |
| FDA UNII | JQ95208805 |
apomine price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0016185 | Apomine 99.67% | 126411-13-0 | 5mg | $368 | 2026-06-04 | Buy |
| ChemScene | CS-0016185 | Apomine 99.67% | 126411-13-0 | 10mg | $531 | 2026-06-04 | Buy |
| ChemScene | CS-0016185 | Apomine 99.67% | 126411-13-0 | 25mg | $861 | 2026-06-04 | Buy |
| ChemScene | CS-0016185 | Apomine 99.67% | 126411-13-0 | 50mg | $1202 | 2026-06-04 | Buy |
| ApexBio Technology | BA3290 | Apomine | 126411-13-0 | 1mg | $121 | 2026-05-06 | Buy |
apomine Chemical Properties, Uses, Production
Uses
Apomine (SR-45023A) is an antineoplastic agent that inhibits the mevalonate/isoprenoid pathway in cholesterol synthesis. Apomine can accelerate the degradation of 3-hydroxy-3-methylglutaryl-CoA reductase (HMGR). Apomine can also inhibit the growth of various types of cancer cells, including lung cancer, colon cancer, breast cancer, and skin cancer. In addition, Apomine is able to induce apoptosis in tumor cell lines derived from leukemia, colon cancer, liver cancer, ovarian cancer, and breast cancer[1].
References
[1] Kuehl PJ, et al. Preformulation, formulation, and in vivo efficacy of topically applied apomine. Int J Pharm. 2009;382(1-2):104-110. DOI:10.1016/j.ijpharm.2009.08.016
apomine Preparation Products And Raw materials
Raw materials
Preparation Products
apomine Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Tianjin Kailiqi Biotechnology Co., Ltd. | 15076683720 | klq@cw-bio.com | China | 9792 | 55 |
| BOC Sciences | 16314854226; +8616314854226 | inquiry@bocsci.com | United States | 19852 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 | psaitong@jm-bio.com | China | 27626 | 58 |
| Aikon International Limited | 17714375163 | hywu@aikonchem.com | China | 9974 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11963 | 58 |
| Nanjing Shizhou Biology Technology Co.,Ltd | 025-85560043 15850508050 | cindy.huang@synzest.com | China | 11975 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29874 | 58 |
| Shanghai Amole Biotechnology Co., Ltd. | 13370042665 18916960931 | 2596183085@qq.com | China | 17234 | 58 |
