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HER2-IN-12

CAS No.
2820126-51-8
Chemical Name:
HER2-IN-12
Synonyms
HER2-IN-12;Imidazo[2,1-b]thiazole-3-carboxylic acid, 5-(4-bromophenyl)-6-(4-morpholinylmethyl)-, hydrazide
CBNumber:
CB413259691
Molecular Formula:
C17H18BrN5O2S
Molecular Weight:
436.33
MDL Number:
MOL File:
2820126-51-8.mol
MSDS File:
SDS
Last updated:2025-05-19 13:47:15

HER2-IN-12 Properties

Density 1.740±0.14 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
pka 10.192±0.20(predicted)

HER2-IN-12 Chemical Properties, Uses, Production

Uses

HER2-IN-12 is a HER2 inhibitor (IC50: 121 nM). HER2-IN-12 can be used in the research of cancers, such as breast cancer[1].

IC 50

HER2: 121 nM (IC50)

References

[1] Mohamed A Sabry, et al. New thiazole-based derivatives as EGFR/HER2 and DHFR inhibitors: Synthesis, molecular modeling simulations and anticancer activity. Eur J Med Chem. 2022 Aug 10;241:114661. DOI:10.1016/j.ejmech.2022.114661

HER2-IN-12 Preparation Products And Raw materials

Raw materials

Preparation Products

HER2-IN-12 Suppliers

Global Suppliers ( 3)
Supplier Tel Email Country ProdList Advantage
Shanghai Beckham Medical Technology Co., Ltd 13816613772 huahero21@sina.com China 2996 55
Tianjin Kailiqi Biotechnology Co., Ltd. 15076683720 klq@cw-bio.com China 9792 55
TargetMol 400-821-0310 15002144251 xuexiang.shao@tsbiochem.com China 29128 58
HER2-IN-12 Imidazo[2,1-b]thiazole-3-carboxylic acid, 5-(4-bromophenyl)-6-(4-morpholinylmethyl)-, hydrazide 2820126-51-8