Tauro-ω-muricholic Acid (sodium salt)
- CAS No.
- 2456348-84-6
- Chemical Name:
- Tauro-ω-muricholic Acid (sodium salt)
- Synonyms
- Tauro-ω-Muricholic Acid Sodium Salt (Standard);Ethanesulfonic acid, 2-[[(3α,5β,6α,7β)-3,6,7-trihydroxy-24-oxocholan-24-yl]amino]-, sodium salt (1:1)
- CBNumber:
- CB413503343
- Molecular Formula:
- C26H45NO7S.Na
- Molecular Weight:
- 538.69
- MDL Number:
- MOL File:
- 2456348-84-6.mol
- MSDS File:
- SDS
Tauro-ω-muricholic Acid (sodium salt) price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 28842 | Tauro-ω-muricholic Acid (sodium salt) ≥95% | 2456348-84-6 | 1mg | $212 | 2026-04-30 | Buy |
| Cayman Chemical | 28842 | Tauro-ω-muricholic Acid (sodium salt) ≥95% | 2456348-84-6 | 5mg | $845 | 2026-04-30 | Buy |
| Cayman Chemical | 28842 | Tauro-ω-muricholic Acid (sodium salt) ≥95% | 2456348-84-6 | 10mg | $1584 | 2026-04-30 | Buy |
| ChemScene | CS-0119476 | Tauro-ω-muricholic acid sodium 97.8% | 2456348-84-6 | 1mg | $628 | 2026-06-04 | Buy |
| ChemScene | CS-0119476 | Tauro-ω-muricholic acid sodium 97.8% | 2456348-84-6 | 5mg | $2004 | 2026-06-04 | Buy |
Tauro-ω-muricholic Acid (sodium salt) Chemical Properties,Uses,Production
Uses
Tauro-ω-muricholic acid sodium (TωMCA sodium) is a bile acid released by the liver and an analog of tauro-α-muricholic acid. Tauro-ω-muricholic acid sodium is investigated as a potential marker in plasma for early-onset neonatal sepsis (EOS) and cholestasis studies[1][2]
in vivo
Sprague–Dawley rats are fed a standard diet with 1 week, and then randomly assigned to the two groups. The control group received a normal diet (10 kcal%), while the NAFLD group is fed a high-fat diet (60 kcal%; 18 weeks)[1].
10 BAs from the NAFLD group are significantly decreased in the liver, including 4 tauro-conjugated BA species including taurolithocholic acid (TLCA), THDCA, taurodeoxycholic acid (TDCA) and tauro ω-muricholic acid (TωMCA). Furthermore, βDCA, HDCA, 6-ketoLCA, 23-nordeoxycholic acid (NorDCA), LCA and 3β-chenodeoxycholic acid (βCDCA) shows lower levels in the NAFLD group[2].
References
[1] Zhrer E, et al. Neonatalsepsisleadstoearlyriseofrareserumbileacidtauro-omega-muricholicacid(TOMCA).Pediatr Res.2018 Jul;84(1):66-70. DOI:10.1038/s41390-018-0007-y
[2] Tang Y, et al. Turnoverofbileacidsinliver,serumandcaecalcontentbyhigh-fatdietfeedingaffectshepaticsteatosisinrats. Biochim Biophys Acta Mol Cell Biol Lipids.2019 Oct;1864(10):1293-1304 DOI:10.1016/j.bbalip.2019.05.016
[3] YOUCAI ZHANG Curtis D K. Effects of feeding bile acids and a bile acid sequestrant on hepatic bile acid composition in mice.[J]. Journal of Lipid Research, 2010, 51 11: 3230-3242. DOI: 10.1194/jlr.m007641
Tauro-ω-muricholic Acid (sodium salt) Preparation Products And Raw materials
Raw materials
Preparation Products
Tauro-ω-muricholic Acid (sodium salt) Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9799 | 58 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
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| Guangzhou Younan Technology Co., Ltd | 020-82000279 18988941452 | YN_research@163.com | China | 2984 | 58 |
| Shanghai Beiwanta Biotechnology Co., Ltd. | 021-67187366 19901745723 | info@bwtlab.com | China | 9884 | 58 |
| SHANGHAI ZZBIO CO., LTD. | 18019219489 18901678489 | tech@zzbioco.com | China | 12062 | 58 |
| ShangHai ZskBio CO., LTD | 021-58056897 15399714481 | info@zsklab.com | China | 7539 | 58 |
| TargetMol | 400-821-0310 15002144251 | xuexiang.shao@tsbiochem.com | China | 29128 | 58 |
| Zhejiang Huida Biotech Co., Ltd. | 0571-89903022 18679456698 | zilong@hizyme.com | China | 7853 | 58 |
