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LY3522348

LY3522348 structure

CAS No.: 2568608-48-8

Chemical Name:: LY3522348

Synonyms: LY3522348;Ethanone, 2-[4-[2-[(2S)-2-methyl-1-azetidinyl]-6-(trifluoromethyl)-4-pyrimidinyl]-1H-pyrazol-1-yl]-1-(1-piperazinyl)-;(S)-2-(4-(2-(2-Methylazetidin-1-yl)-6-(trifluoromethyl)pyrimidin-4-yl)-1H-pyrazol-1-yl)-1-(piperazin-1-yl)ethan-1-one

CBNumber:: CB413811642

Molecular Formula:: C18H22F3N7O

Molecular Weight:: 409.41

MDL Number:

MOL File:: 2568608-48-8.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-28 01:17:22

Request For Quotation

LY3522348 Properties

Boiling point	617.799±65.00 °C(Press: 760.00 Torr)(predicted)
Density	1.517±0.14 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
pka	8.368±0.10(predicted)
form	Solid
color	Off-white to yellow

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319
Precautionary statements	P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

LY3522348 price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
ChemScene	CS-0781652	LY3522348 98.30%	2568608-48-8	5mg	$217	2026-06-04	Buy
ChemScene	CS-0781652	LY3522348 98.30%	2568608-48-8	10mg	$347	2026-06-04	Buy
ChemScene	CS-0781652	LY3522348 98.30%	2568608-48-8	25mg	$628	2026-06-04	Buy
ChemScene	CS-0781652	LY3522348 98.30%	2568608-48-8	50mg	$817	2026-06-04	Buy
ChemScene	CS-0781652	LY3522348 98.30%	2568608-48-8	100mg	$1062	2026-06-04	Buy

Product number	Packaging	Price	Buy
CS-0781652	5mg	$217	Buy
CS-0781652	10mg	$347	Buy
CS-0781652	25mg	$628	Buy
CS-0781652	50mg	$817	Buy
CS-0781652	100mg	$1062	Buy

LY3522348 Chemical Properties, Uses, Production

Uses

KHK-IN-3 (Example 1) is a ketohexokinase (KHK) inhibitor. KHK-IN-3 can be used in the study of kidney disease, nonalcoholic steatohepatitis (NASH), diabetes and heart failure. KHK is a rate-limiting enzyme and fructokinase involved in fructose metabolism. KHK catalyzes the phosphorylation of fructose to fructose-1-phosphate (FIP) at the expense of ATP. The lack of feedback inhibition of fructose metabolism triggers the accumulation of downstream intermediates such as lipogenesis, gluconeogenesis, and oxidative phosphorylation[1].

References

[1] Coates David Andrew, et al. Preparation of the disubstituted pyrazole compound and their medical applications. United States, US20200392118 A1. 2020-12-17.

LY3522348 Preparation Products And Raw materials

Raw materials

Preparation Products

LY3522348 Suppliers

Global Suppliers ( 7)

Supplier	Tel	Email	Country	ProdList	Advantage
WUHAN SUN-SHINE BIO-TECHNOLOGY Co., Ltd.	17702719238	sales@sun-shinechem.com	China	1197	64
ShangHai ChuanQian Chemcial Technique Centre	15869524721	3525679403@qq.com	China	4565	58
Bide Pharmatech Ltd.	400-1647117 13681763483	product02@bidepharm.com	China	59929	58
Shanghai Tachizaki Biomedical Research Center	18014399201	sales@chemlab-tachizaki.com	China	2934	58
TargetMol Chemicals Inc.	15002134094	marketing@targetmol.cn	China	29874	58
Wuhan Xinsengyang Biotechnology Co., Ltd	18402740988 18402740988	3879363529@qq.com	China	1000	58

Supplier	Advantage
WUHAN SUN-SHINE BIO-TECHNOLOGY Co., Ltd.	64
ShangHai ChuanQian Chemcial Technique Centre	58
Bide Pharmatech Ltd.	58
Shanghai Tachizaki Biomedical Research Center	58
TargetMol Chemicals Inc.	58
Wuhan Xinsengyang Biotechnology Co., Ltd	58

2568608-48-8 (LY3522348) Related Search:

1-[4-(1-ethyl-1H-pyrazol-4-yl)-6-(trifluoromethyl)pyrimidin-2-yl]piperidin-4-amine LY3522348 tert-butyl (S)-4-(2-(4-(2-(2-methylazetidin-1-yl)-6-(trifluoromethyl)pyrimidin-4-yl)-1H-pyrazol-1-yl)acetyl)piperazine-1-carboxylate (S)-2-(4-(2-(2-methylazetidin-1-yl)-6-(trifluoromethyl)pyrimidin-4-yl)-1H-pyrazol-1-yl)acetic acid KHK-IN-5

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LY3522348 (S)-2-(4-(2-(2-Methylazetidin-1-yl)-6-(trifluoromethyl)pyrimidin-4-yl)-1H-pyrazol-1-yl)-1-(piperazin-1-yl)ethan-1-one Ethanone, 2-[4-[2-[(2S)-2-methyl-1-azetidinyl]-6-(trifluoromethyl)-4-pyrimidinyl]-1H-pyrazol-1-yl]-1-(1-piperazinyl)- 2568608-48-8