beta-endorphin (6-31)
- CAS No.
- 77761-27-4
- Chemical Name:
- beta-endorphin (6-31)
- Synonyms
- beta-endorphin (6-31);6-31-β-Endorphin (human);b-Lipotropin (64-89) (huMan);4 β-Endorphin (6-31) (human);β-Lipotropin (64-89) (human);6-31-b-Endorphin (sheep),27-L-tyrosine-31-L-glutamic acid;6-31-β-Endorphin (sheep), 27-L-tyrosine-31-L-glutamic acid-;H-Thr-Ser-Glu-Lys-Ser-Gln-Thr-Pro-Leu-Val-Thr-Leu-Phe-Lys-Asn-Ala-Ile-Ile-Lys-Asn-Ala-Tyr-Lys-Lys-Gly-Glu-OH
- CBNumber:
- CB41394797
- Molecular Formula:
- C131H218N34O40
- Molecular Weight:
- 2909.36
- MDL Number:
- MOL File:
- 77761-27-4.mol
Product description | Number | Pack Size | Price |
Beta-Endorphin (6-31) > 95% | orb364362 | 1mg | $479.4 |
Beta-Endorphin (6-31) > 95% | orb364362 | 5mg | $1016.6 |
Beta-Endorphin (6-31) > 95% | orb364362 | 10mg | $1518.1 |
beta-endorphin (6-31) price More Price(3)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Biorbyt Ltd | orb364362 | Beta-Endorphin (6-31) > 95% | 77761-27-4 | 1mg | $479.4 | 2021-12-16 | Buy |
Biorbyt Ltd | orb364362 | Beta-Endorphin (6-31) > 95% | 77761-27-4 | 5mg | $1016.6 | 2021-12-16 | Buy |
Biorbyt Ltd | orb364362 | Beta-Endorphin (6-31) > 95% | 77761-27-4 | 10mg | $1518.1 | 2021-12-16 | Buy |
beta-endorphin (6-31) Chemical Properties,Uses,Production
Uses
β-Endorphin, an endogenous opioid neuropeptide, is an opioid receptor agonist. β-Endorphin binds preferentially to μ-opioid receptors and is produced in certain neurons of the central and peripheral nervous system and is one of three endorphins produced in humans. β-Endorphin can be used to reduce stress and maintain homeostasis in the body and is involved in neurological pain perception regulation[1].
in vivo
β-Endorphin (0.03 to 1.00?μg/kg, i.p., once) impairs retention of a one-trial inhibitory avoidance task in a dose-dependent manner in male Swiss mice immediately post-training. Also, it works in the process of memory consolidation[1].
Animal Model: | Adult male Swiss mice (22-25 g)[1] |
Dosage: | 0.03, 0.10, 0.30 or 1.00 μg/kg |
Administration: | i.p., once |
Result: | Significantly impaired retention at the doses of 0.03 and 0.10?μg/kg while not significantly affect retention as compared with the control group at the two higher doses of 0.30 and 1.00?μg/kg , but tended to increase retention as compared with the dose of 0.10?μg/kg. Increased latencies to step-through at the two higher doses of 0.30 and 1.00?μg/kg but no effect at lower doses. |
References
[1] Introini IB, et al. The impairment of retention induced by beta-endorphin in mice may be mediated by a reduction of central cholinergic activity. Behav Neural Biol. 1984 Jul;41(2):152-63. DOI:10.1016/s0163-1047(84)90527-2
beta-endorphin (6-31) Preparation Products And Raw materials
Raw materials
Preparation Products
beta-endorphin (6-31) Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
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Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10405 | 58 |
Hangzhou Go Top Peptide Biotech | 0571-88211921 | sales1@gotopbio.com | CHINA | 2609 | 58 |
Chengdu Youngshe Chemical Co., Ltd. | +8618108235634 | Cecilia@youngshechem.com | China | 2345 | 58 |
Nanjing TGpeptide | +86-13347807150 | support@tgpeptide.com | China | 3279 | 58 |
Changsha MOL Changes Biotechnology Co., Ltd. | +8619375158599 | info@molchanges.com | China | 5218 | 58 |
Moxin Chemicals | +86-17320513646 +8617320513646 | anna@molcoo.com | China | 10000 | 58 |
Chemsky (shanghai) International Co.,Ltd | 021-50135380 | shchemsky@sina.com | China | 15402 | 60 |
BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 12952 | 65 |
Nanjing Leon Biological Technology Co., Ltd. | 17705183659 | sales@njleonbiotech.com | China | 5501 | 55 |
Nanjing Peptide Biotech Ltd. | 025-58361106-805 15951641583 | zhao.xu@njpeptide.com | China | 9979 | 55 |
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