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ChemicalBook >> CAS DataBase List >>8-Benzyl-3-exo-(5-isopropyl-3-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane

8-Benzyl-3-exo-(5-isopropyl-3-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane

8-Benzyl-3-exo-(5-isopropyl-3-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane Structure
8-Benzyl-3-exo-(5-isopropyl-3-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane structure
CAS No.
423165-13-3
Chemical Name:
8-Benzyl-3-exo-(5-isopropyl-3-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane
Synonyms
Maraviroc interMediate(Tropine aMine );-8-Benzyl-3-(3-isopropyl-5-methyl-4H-1,2,4-triazol-4-yl);8-Benzyl-3-exo-(5-isopropyl-3-methyl-4H-1,2,4-triazol-4-yl)-...;8-benzyl-3-(3-isopropyl-5-Methyl-4H-1,2,4-triazol-4-yl)-8-aza-bicyclo[3.2.1]octane;8-BENZYL-3-EXO-(3-ISOPROPYL-5-METHYL-4H-1,2,4-TRIAZOL-4-YL)-8-AZABICYCLO[3.2.1]OCTANE;exo-8-Benzyl-3-(3-isopropyl-5-Methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane;8-Benzyl-3-exo-(5-isopropyl-3-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane;(3-exo)-8-Benzyl-(5-isopropyl-3-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane;exo-8-benzyl-3-[3-methyl-5-(propan-2-yl)-4H-1,2,4-triazol-4-yl]-8-azabicyclo[3.2.1]octane;(1R,3s,5S)-8-Benzyl-3-(3-isopropyl-5-Methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane
CBNumber:
CB41475489
Molecular Formula:
C20H28N4
Molecular Weight:
324.46
MDL Number:
MFCD12911892
MOL File:
423165-13-3.mol
MSDS File:
SDS
Last updated:2026-05-28 01:19:15
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8-Benzyl-3-exo-(5-isopropyl-3-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane Properties

Melting point 149 ºC
Boiling point 481.5±55.0 °C(Predicted)
Density 1.20
storage temp. 2-8°C
solubility soluble in Chloroform, Dichloromethane
pka 9.71±0.40(Predicted)
form Solid
color Brown
InChI InChI=1/C20H28N4/c1-14(2)20-22-21-15(3)24(20)19-11-17-9-10-18(12-19)23(17)13-16-7-5-4-6-8-16/h4-8,14,17-19H,9-13H2,1-3H3/t17-,18+,19-
InChIKey YHGHRIAZABSSGB-REPLKXPHNA-N
SMILES C1C[C@]2([H])C[C@@H](N3C(C(C)C)=NN=C3C)C[C@@]1([H])N2CC1C=CC=CC=1 |&1:2,5,16,r|
FDA UNII YLC8DY2K99

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)Corrosion (GHS05)
GHS07,GHS05
Signal word  Danger
Hazard statements  H302-H412-H318
Precautionary statements  P273-P501-P264-P270-P301+P312-P330-P501-P280-P305+P351+P338-P310

8-Benzyl-3-exo-(5-isopropyl-3-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane price More Price(21)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological 003591 8-Benzyl-3-(3-isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-exo-8-azabicyclo[3.2.1]octane 423165-13-3 10mg $446 2026-06-03 Buy
Chem-Impex 29374 8-Benzyl-3-exo-(5-isopropyl-3-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane 423165-13-3 10MG $173.66 2026-05-19 Buy
Chem-Impex 29374 8-Benzyl-3-exo-(5-isopropyl-3-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane 423165-13-3 25MG $362.54 2026-05-19 Buy
Matrix Scientific 090862 Exo-8-Benzyl-3-(3-isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane 423165-13-3 250.00mg $1872 2026-05-18 Buy
aablocks AA00BXVM 8-benzyl-3-(3-isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-aza-bicyclo[3.2.1]octane 95+% 423165-13-3 10mg $300 2026-05-28 Buy
Product number Packaging Price Buy
003591 10mg $446 Buy
29374 10MG $173.66 Buy
29374 25MG $362.54 Buy
090862 250.00mg $1872 Buy
AA00BXVM 10mg $300 Buy

8-Benzyl-3-exo-(5-isopropyl-3-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane Chemical Properties,Uses,Production

Chemical Properties

Brown Solid

Synthesis

A solution of N-(8-benzyl-8-aza-bicyclo[3.2.1]oct-3-yl)-isobutyramide in dichloromethane was slowly added to a slurry of phosphorous pentachloride in dichloromethane at 0 °C, and the mixture was allowed to warm to ambient temperature over 2 hours. The resulting solution was cooled to 0°C, and a solution of acetyl hydrazide in amyl alcohol was slowly added at 10 °C. The reaction was stirred at ambient temperature overnight. The mixture was then cooled to 0°C and treated with 2N sodium hydroxide at 20°C, and the pH was adjusted to 9 with 30% aqueous sodium hydroxide. The organic layer was separated and the aqueous layer was extracted with dichloromethane. The combined organic layers were dried and concentrated to about volume. Ethyl acetate and acetic acid were added and the mixture was heated to 80° C for 1 hour, cooled to ambient temperature and stirred overnight. The solution was cooled to 0°C and the pH was adjusted to about 12 with 2N sodium hydroxide. The organic layer was separated and the aqueous layer was extracted with ethyl acetate. The combined organic layers were dried and concentrated to give 8-Benzyl-3-(3-isopropyl-5-methyl-4h-1,2,4-triazol-4-yl)-8-aza-bicyclo[3.2.1]octane. Yield: 65%.
8-Benzyl-3-(3-isopropyl-5-methyl-4h-1,2,4-triazol-4-yl)-8-aza-bicyclo[3.2.1]octane

8-Benzyl-3-exo-(5-isopropyl-3-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane Preparation Products And Raw materials

Raw materials

Preparation Products

(1R,3s,5S)-3-(3-Isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane 3-(3-Isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane-p-toluenesulfonate

8-Benzyl-3-exo-(5-isopropyl-3-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane Suppliers

Global( 60)Suppliers
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Beijing Mediking Biopharm Co., Ltd 010-81769521,89753524,81760121 15901403431 sales01@mediking.cn China 100 68
Shanghai Scientia Pharmaceutical Technology Co., Ltd. 21-21-54301573 13917723525 sales@scientiapharm.com China 260 62
Nanjing Chemlin Chemical Co., Ltd 025-83697070 13770331960 info@chemlin.com.cn China 16305 64
Chemsky（shanghai）International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32273 50
Beijing HuaMeiHuLiBiological Chemical 010-56205725 waley188@sohu.com China 12323 58
China Nobel Chem Co., Limited +86(0)21 60484900 China 762 50
Shanghai Yudiao Chemistry Technology Co.,Ltd 021-37285211 18964703211 info@yudiaochem.com China 120 58
Shanghai AQBioPharma Co., Ltd. 13661411401 yinglv.que@aqbiopharma.com.cn China 2976 58
Shanghai QianYan Bio-technology Co., Ltd 02781293128 orders@biochemsafebuy.com China 9904 55
Supplier Advantage
J & K SCIENTIFIC LTD. 76
Beijing Mediking Biopharm Co., Ltd 68
Shanghai Scientia Pharmaceutical Technology Co., Ltd. 62
Nanjing Chemlin Chemical Co., Ltd 64
Chemsky（shanghai）International Co.,Ltd. 50
Beijing HuaMeiHuLiBiological Chemical 58
China Nobel Chem Co., Limited 50
Shanghai Yudiao Chemistry Technology Co.,Ltd 58
Shanghai AQBioPharma Co., Ltd. 58
Shanghai QianYan Bio-technology Co., Ltd 55

View Lastest Price from 8-Benzyl-3-exo-(5-isopropyl-3-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
8-BENZYL-3-EXO-(3-ISOPROPYL-5-METHYL-4H-1,2,4-TRIAZOL-4-YL)-8-AZABICYCLO[3.2.1]OCTANE pictures 2025-12-24 8-BENZYL-3-EXO-(3-ISOPROPYL-5-METHYL-4H-1,2,4-TRIAZOL-4-YL)-8-AZABICYCLO[3.2.1]OCTANE
423165-13-3
 1KG 99.0% 1000 tons Shaanxi Dideu Medichem Co. Ltd
8-BENZYL-3-EXO-(3-ISOPROPYL-5-METHYL-4H-1,2,4-TRIAZOL-4-YL)-8-AZABICYCLO[3.2.1]OCTANE pictures 2025-06-20 8-BENZYL-3-EXO-(3-ISOPROPYL-5-METHYL-4H-1,2,4-TRIAZOL-4-YL)-8-AZABICYCLO[3.2.1]OCTANE
423165-13-3
 1kg 0.99 20tons Hebei Yanxi Chemical Co., Ltd.
8-Benzyl-3-exo-(5-isopropyl-3-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane pictures 2022-01-18 8-Benzyl-3-exo-(5-isopropyl-3-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane
423165-13-3
 1KG 97.6% 100 tons Honest Joy Holdings Limited

423165-13-3(8-Benzyl-3-exo-(5-isopropyl-3-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane )Related Search:

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exo-8-benzyl-3-[3-methyl-5-(propan-2-yl)-4H-1,2,4-triazol-4-yl]-8-azabicyclo[3.2.1]octane 8-Benzyl-3-exo-(5-isopropyl-3-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane 8-Azabicyclo[3,2,1]octane3-[3-methyl-5-(1-methlethyl)-4H-1,2,4-triazol-4-yl]-8-(phenylmethyl) exo-8-Benzyl-3-(3-isopropyl-5-Methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane 3-[3-Methyl-5-(1-Methylethyl)-4H-1,2,4-triazol-4-yl]-8-(phenylMethyl)-(3-exo)-8-azabicyclo[3.2.1]octane Maraviroc interMediate(Tropine aMine ) 8-Azabicyclo[3.2.1]octane,3-[3-Methyl-5-(1-Methylethyl)-4H-1,2,4-triazol-4-yl]-8-(phenylMethyl)-,(3-exo)- (1R,3s,5S)-8-Benzyl-3-(3-isopropyl-5-Methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane -8-Benzyl-3-(3-isopropyl-5-methyl-4H-1,2,4-triazol-4-yl) 8-BENZYL-3-EXO-(3-ISOPROPYL-5-METHYL-4H-1,2,4-TRIAZOL-4-YL)-8-AZABICYCLO[3.2.1]OCTANE (3-exo)-3-[3-Methyl-5-(1-methylethyl)-4H-1,2,4-triazol- 4-yl] -8-(phenylmethyl)-8-azabicyclo[3.2.1]octane 8-Benzyl-3-exo-(5-isopropyl-3-methyl-4H-1,2,4-triazol-4-yl)-... 8-benzyl-3-(3-isopropyl-5-Methyl-4H-1,2,4-triazol-4-yl)-8-aza-bicyclo[3.2.1]octane (3-exo)-8-Benzyl-(5-isopropyl-3-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane (3-exo)-3-[3-Methyl-5-(1-methylethyl)-4H-[1,2,4]-triazol-4-yl]-8-(benzyl)-8-azabicyclo[3.2.1]octane 423165-13-3