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PYRAZOLO[1,5-A]PYRAZINE-2-CARBOXYLIC ACID, 4,5,6,7-TETRAHYDRO-4-OXO-, ETHYL ESTER

PYRAZOLO[1,5-A]PYRAZINE-2-CARBOXYLIC ACID, 4,5,6,7-TETRAHYDRO-4-OXO-, ETHYL ESTER structure

CAS No.: 951626-95-2

Chemical Name:: PYRAZOLO[1,5-A]PYRAZINE-2-CARBOXYLIC ACID, 4,5,6,7-TETRAHYDRO-4-OXO-, ETHYL ESTER

Synonyms: KML-98;KML-67;Ethyl 4-oxo-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine-2-carb;ethyl 4-oxo-4H,5H,6H,7H-pyrazolo[1,5-a]pyrazine-2-carboxylate;4-oxo-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine-2-carboxylate;ethyl 4-oxo-6,7-dihydro-5H-pyrazolo[1,5-a]pyrazine-2-carboxylate;PYRAZOLO[1,5-A]PYRAZINE-2-CARBOXYLIC ACID, 4,5,6,7-TETRAHYDRO-4-OXO-, ETHYL ESTER

CBNumber:: CB41502244

Molecular Formula:: C9H11N3O3

Molecular Weight:: 209.2

MDL Number:: MFCD09832110

MOL File:: 951626-95-2.mol

MSDS File:: SDS

Last updated:2026-05-28 02:05:01

Product description	Number	Pack Size	Price
Ethyl 4-oxo-4,5,6,7-tetrahydropyrazolo- [1,5-a]pyrazine-2-carboxylate	124249	250.00mg	$33
Ethyl 4-oxo-4,5,6,7-tetrahydropyrazolo- [1,5-a]pyrazine-2-carboxylate	124249	1.00g	$71
Ethyl 4-oxo-4,5,6,7-tetrahydropyrazolo- [1,5-a]pyrazine-2-carboxylate	124249	5.00g	$291
Ethyl 4-oxo-4,5,6,7-tetrahydropyrazolo [1,5-a]pyrazine-2-carboxylate 95+%	E14694	250mg	$30
Ethyl 4-oxo-4,5,6,7-tetrahydropyrazolo [1,5-a]pyrazine-2-carboxylate 95+%	E14694	500mg	$45
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Request For Quotation

PYRAZOLO[1,5-A]PYRAZINE-2-CARBOXYLIC ACID, 4,5,6,7-TETRAHYDRO-4-OXO-, ETHYL ESTER Properties

Boiling point	504.8±45.0 °C(Predicted)
Density	1.48±0.1 g/cm3(Predicted)
storage temp.	Sealed in dry,Room Temperature
pka	13.84±0.20(Predicted)
Appearance	White to off-white Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H335-H315-H332-H319-H302
Precautionary statements	P264-P270-P301+P312-P330-P501-P264-P280-P302+P352-P321-P332+P313-P362-P261-P271-P304+P340-P312-P264-P280-P305+P351+P338-P337+P313P

PYRAZOLO[1,5-A]PYRAZINE-2-CARBOXYLIC ACID, 4,5,6,7-TETRAHYDRO-4-OXO-, ETHYL ESTER price More Price(56)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Matrix Scientific	124249	Ethyl 4-oxo-4,5,6,7-tetrahydropyrazolo- [1,5-a]pyrazine-2-carboxylate	951626-95-2	250.00mg	$33	2026-05-18	Buy
Matrix Scientific	124249	Ethyl 4-oxo-4,5,6,7-tetrahydropyrazolo- [1,5-a]pyrazine-2-carboxylate	951626-95-2	1.00g	$71	2026-05-18	Buy
Matrix Scientific	124249	Ethyl 4-oxo-4,5,6,7-tetrahydropyrazolo- [1,5-a]pyrazine-2-carboxylate	951626-95-2	5.00g	$291	2026-05-18	Buy
Synthonix	E14694	Ethyl 4-oxo-4,5,6,7-tetrahydropyrazolo [1,5-a]pyrazine-2-carboxylate 95+%	951626-95-2	250mg	$30	2026-05-06	Buy
Synthonix	E14694	Ethyl 4-oxo-4,5,6,7-tetrahydropyrazolo [1,5-a]pyrazine-2-carboxylate 95+%	951626-95-2	500mg	$45	2026-05-06	Buy

Product number	Packaging	Price	Buy
124249	250.00mg	$33	Buy
124249	1.00g	$71	Buy
124249	5.00g	$291	Buy
E14694	250mg	$30	Buy
E14694	500mg	$45	Buy

PYRAZOLO[1,5-A]PYRAZINE-2-CARBOXYLIC ACID, 4,5,6,7-TETRAHYDRO-4-OXO-, ETHYL ESTER Chemical Properties,Uses,Production

Synthesis

1H-Pyrazole-3,5-dicarboxylic acid, 1-[2-[[(1,1-dimethylethoxy)carbonyl]amino]ethyl]-, 3,5-diethyl ester

1380507-24-3

PYRAZOLO[1,5-A]PYRAZINE-2-CARBOXYLIC ACID, 4,5,6,7-TETRAHYDRO-4-OXO-, ETHYL ESTER

951626-95-2

Diethyl 1-(3-tert-butoxycarbonylaminoethyl)-1H-pyrazole-3,5-dicarboxylate (2.4 g, 6.7 mmol) was dissolved in a dioxane solution (25 mL) of 4 N hydrochloric acid under nitrogen atmosphere. The reaction mixture was stirred at room temperature for 1 h before being alkalized with saturated sodium carbonate solution and extracted with dichloromethane. The organic phase was separated, washed with saturated saline, dried over anhydrous sodium sulfate, filtered and the solvent concentrated under reduced pressure. The crude product was purified by fast column chromatography (silica gel as stationary phase, eluent dichloromethane/methanol solution containing 7 M ammonia, gradient from 0/100 to 5/95). The target fraction was collected and the solvent was removed under reduced pressure to afford ethyl 4-oxo-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine-2-carboxylate (1.1 g, 79% yield) as a white solid. The molecular formula of the compound is C9H11N3O3 and the LCMS analysis resulted in a retention time of 0.49 min and a mass-to-charge ratio of m/z 210 [M+H]+ (refer to LCMS method 1).

References

[1] Patent: WO2012/78817, 2012, A1. Location in patent: Page/Page column 140
[2] Patent: WO2012/83224, 2012, A1. Location in patent: Page/Page column 266
[3] Patent: WO2013/192350, 2013, A1. Location in patent: Paragraph 00591
[4] Bioorganic and Medicinal Chemistry Letters, 2016, vol. 26, # 2, p. 429 - 434
[5] Patent: US2015/361081, 2015, A1. Location in patent: Paragraph 0480

PYRAZOLO[1,5-A]PYRAZINE-2-CARBOXYLIC ACID, 4,5,6,7-TETRAHYDRO-4-OXO-, ETHYL ESTER Preparation Products And Raw materials

Raw materials

2-Chloroethylamine hydrochloride 1H-Pyrazole-3,5-dicarboxylic acid, 1-[2-[[(1,1-dimethylethoxy)carbonyl]amino]ethyl]-, 3,5-diethyl ester DIETHYL 3,5-PYRAZOLEDICARBOXYLATE Dichloromethane Methanol

1,4-Dioxane Ammonia Hydrochloric acid

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Preparation Products

PYRAZOLO[1,5-A]PYRAZINE-2-CARBOXYLIC ACID, 4,5,6,7-TETRAHYDRO-4-OXO-, ETHYL ESTER Suppliers

Global( 78)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
Accela ChemBio Inc.	+1-858-6993322	info@accelachem.com	United States	21193	58
Career Henan Chemica Co	+86-0371-86658258 +8613203830695	laboratory@coreychem.com	China	30225	58
Shanxi Xuanran Import and Export Trade Co., Ltd.	+8617735180244	mike_yan@xuanranglobal.com	CHINA	4017	58
Hefei Hirisun Pharmatech Co., Ltd	+8615056975894	shawn@hirisunpharm.com	CHINA	9911	58
Labnetwork lnc.	+86-27-50766799 +8618062016861	contact@labnetwork.com	China	19987	58
Shanxi Tihondan Pharmaceutical Technology Co., Ltd	+8618235132063	sales@tihondan.com	China	3767	58
Aladdin Scientific		tp@aladdinsci.com	United States	52923	58
Suzhou ARTK Medchem Co., Ltd.	+8618118463618	sales1@artkmedchem.com	China	39021	58
Chongqing Chemdad Co., Ltd	+86-023-6139-8061 +86-86-13650506873	sales@chemdad.com	China	39927	58

Supplier	Advantage
ATK CHEMICAL COMPANY LIMITED	60
Accela ChemBio Inc.	58
Career Henan Chemica Co	58
Shanxi Xuanran Import and Export Trade Co., Ltd.	58
Hefei Hirisun Pharmatech Co., Ltd	58
Labnetwork lnc.	58
Shanxi Tihondan Pharmaceutical Technology Co., Ltd	58
Aladdin Scientific	58
Suzhou ARTK Medchem Co., Ltd.	58
Chongqing Chemdad Co., Ltd	58

PYRAZOLO[1,5-A]PYRAZINE-2-CARBOXYLIC ACID, 4,5,6,7-TETRAHYDRO-4-OXO-, ETHYL ESTER Spectrum

PYRAZOLO[1,5-A]PYRAZINE-2-CARBOXYLIC ACID, 4,5,6,7-TETRAHYDRO-4-OXO-, ETHYL ESTER(951626-95-2)¹HNMR

951626-95-2(PYRAZOLO[1,5-A]PYRAZINE-2-CARBOXYLIC ACID, 4,5,6,7-TETRAHYDRO-4-OXO-, ETHYL ESTER)Related Search:

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PYRAZOLO[1,5-A]PYRAZINE-2-CARBOXYLIC ACID, 4,5,6,7-TETRAHYDRO-4-OXO-, ETHYL ESTER 4-oxo-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine-2-carboxylate ethyl 4-oxo-4H,5H,6H,7H-pyrazolo[1,5-a]pyrazine-2-carboxylate ethyl 4-oxo-6,7-dihydro-5H-pyrazolo[1,5-a]pyrazine-2-carboxylate KML-67 KML-98 Ethyl 4-oxo-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine-2-carb 951626-95-2