ChemicalBook >> CAS DataBase List >>3-AMINO-8-BENZYL-8-AZABICYCLO[3.2.1]OCTANE (3-EXO)-

3-AMINO-8-BENZYL-8-AZABICYCLO[3.2.1]OCTANE (3-EXO)-

3-AMINO-8-BENZYL-8-AZABICYCLO[3.2.1]OCTANE (3-EXO)- structure

CAS No.: 76272-36-1

Chemical Name:: 3-AMINO-8-BENZYL-8-AZABICYCLO[3.2.1]OCTANE (3-EXO)-

Synonyms: 8-benzyl-8-azabicyclo[3.2.1]octan-1-aMine;8-Benzyl-8-azabycyclo (3.2.1)octan-3-amine;Benzyl-8-azabicyclo[3.2.1]octan-3-exo-amine;exo-3-ami-8-benzyl-8-azabicyclo[3.2.1]octane;exo-8-Benzyl-8-azabicyclo[3.2.1]octan-3-aMine;8-Benzyl-8-azabicyclo[3.2.1]octan-3-exo-amine;exo-3-amino-8-benzyl-8-azabicyclo[3.2.1]octane;8-Benzyl-8-azabicyclo[3.2.1]octane-3-exo-amino;exo-8-benzyl-8-azabiscyclo[3.2.1]octyl-3-amine;(exo-8-Benzyl-8-azabicyclo[3.2.1]oct-3-yl)aMine

CBNumber:: CB41504051

Molecular Formula:: C14H20N2

Molecular Weight:: 216.33

MDL Number:: MFCD09753144

MOL File:: 76272-36-1.mol

MSDS File:: SDS

Last updated:2026-05-28 02:06:19

Product description	Number	Pack Size	Price
Benzyl-8-azabicyclo[3.2.1]octan-3-exo-amine	TRC-B230760-500MG	500mg	$223
Benzyl-8-azabicyclo[3.2.1]octan-3-exo-amine	TRC-B230760-250MG	250mg	$129
Benzyl-8-azabicyclo[3.2.1]octan-3-exo-amine	TRC-B230760-1G	1g	$326
exo 8-Benzyl-8-azabicyclo[3.2.1]octan-3-amine 97%	AS31992-exo	1g	$181
exo 8-Benzyl-8-azabicyclo[3.2.1]octan-3-amine 97%	AS31992-exo	5g	$525
More product size

Request For Quotation

3-AMINO-8-BENZYL-8-AZABICYCLO[3.2.1]OCTANE (3-EXO)- Properties

Boiling point	110-115 °C(Press: 0.05 Torr)
Density	1.082±0.06 g/cm3(Predicted)
storage temp.	under inert gas (nitrogen or Argon) at 2–8 °C
solubility	Chloroform (Slightly), Methanol (Slightly)
pka	10.23±0.20(Predicted)
form	Oil
color	Clear Light yellow to Beige

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H315-H319-H335
Precautionary statements	P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P362-P403+P233-P501

3-AMINO-8-BENZYL-8-AZABICYCLO[3.2.1]OCTANE (3-EXO)- price More Price(60)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TRC	TRC-B230760-500MG	Benzyl-8-azabicyclo[3.2.1]octan-3-exo-amine	76272-36-1	500mg	$223	2026-06-03	Buy
TRC	TRC-B230760-250MG	Benzyl-8-azabicyclo[3.2.1]octan-3-exo-amine	76272-36-1	250mg	$129	2026-06-03	Buy
TRC	TRC-B230760-1G	Benzyl-8-azabicyclo[3.2.1]octan-3-exo-amine	76272-36-1	1g	$326	2026-06-03	Buy
Activate Scientific	AS31992-exo	exo 8-Benzyl-8-azabicyclo[3.2.1]octan-3-amine 97%	76272-36-1	1g	$181	2026-06-04	Buy
Activate Scientific	AS31992-exo	exo 8-Benzyl-8-azabicyclo[3.2.1]octan-3-amine 97%	76272-36-1	5g	$525	2026-06-04	Buy

Product number	Packaging	Price	Buy
TRC-B230760-500MG	500mg	$223	Buy
TRC-B230760-250MG	250mg	$129	Buy
TRC-B230760-1G	1g	$326	Buy
AS31992-exo	1g	$181	Buy
AS31992-exo	5g	$525	Buy

3-AMINO-8-BENZYL-8-AZABICYCLO[3.2.1]OCTANE (3-EXO)- Chemical Properties,Uses,Production

Uses

Intermediate in the preparation of CCR5 receptor antagonists, antibacterial agents and dopamine antagonists

Synthesis

76272-34-9

3-AMINO-8-BENZYL-8-AZABICYCLO[3.2.1]OCTANE (3-EXO)-

76272-36-1

General procedure for the synthesis of exo-8-benzyl-8-azabicyclo[3.2.1]octan-3-one oxime from 8-benzyl-8-azabicyclo[3.2.1]octan-3-amine:[105] 8-benzyl-8-azabicyclo[3.2.1]octan-3-one oxime (7.65 g, 33 mmol) was dissolved in 1-pentanol (130 mL) at 120 °C. Sodium metal (7.6 g, 0.33 mol, 10.0 eq.) was added in batches over 2 hours. The mixture was stirred and heated under reflux conditions for 5 hours, then cooled to 5°C. The reaction mixture was slowly acidified with 6 M HCl until the pH reached acidic, and then the aqueous phase was further extracted with 6 M HCl (3 x 100 mL). The aqueous layer was gradually alkalized to pH 10 by addition of 5 M NaOH. the resulting aqueous solution was extracted with EtOAc (3 × 100 mL). The organic extracts were combined, dried with MgSO4, filtered and concentrated in vacuum. The crude product was purified by column chromatography (5-10% MeOH/CH2Cl2) to afford pure exo-8-benzyl-8-azabicyclo[3.2.1]octan-3-amine as a solid (2.60 g, 36%).

References

[1] Journal of Medicinal Chemistry, 2018, vol. 61, # 11, p. 5020 - 5033
[2] Journal of Heterocyclic Chemistry, 1982, vol. 19, # 3, p. 485 - 488
[3] Patent: WO2008/63600, 2008, A2. Location in patent: Page/Page column 11-12; 26
[4] ACS Medicinal Chemistry Letters, 2014, vol. 5, # 2, p. 133 - 137
[5] Medicinal Chemistry Research, 2018, vol. 27, # 8, p. 1906 - 1928

3-AMINO-8-BENZYL-8-AZABICYCLO[3.2.1]OCTANE (3-EXO)- synthesis

Synthesis of 3-AMINO-8-BENZYL-8-AZABICYCLO[3.2.1]OCTANE (3-EXO)- from 1,3-Acetonedicarboxylic acid

3-AMINO-8-BENZYL-8-AZABICYCLO[3.2.1]OCTANE (3-EXO)- Preparation Products And Raw materials

Raw materials

8-Azabicyclo[3.2.1]octan-3-one, 8-methyl-, oxime 8-BENZYL-1AH,5AH-NORTROPAN-3-ONE OXIME N-Benzyltropinone 1,3-Acetonedicarboxylic acid Hydrochloric acid

Sodium hydroxide Nortropan-3-one Sodium Tropinone Benzylamine

1of2

Preparation Products

exo-3-Boc-aminotropane

3-AMINO-8-BENZYL-8-AZABICYCLO[3.2.1]OCTANE (3-EXO)- Suppliers

Global( 78)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Yanxi Chemical Co., Ltd.	+8618531123677	faithe@yan-xi.com	China	5853	58
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29815	58
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	10403	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
Shaanxi Dideu Medichem Co. Ltd	+86-29-81139210 +86-18192627656	1059@dideu.com	China	3587	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	+8613580539051	joe@yuhengpharm.com	CHINA	21142	58
Shanghai Yudiao Chemistry Technology Co.,Ltd	02137285211 18964703211	info@yudiaochem.com	CHINA	238	58
Career Henan Chemica Co	+86-0371-86658258 +8613203830695	laboratory@coreychem.com	China	30225	58
Dayang Chem (Hangzhou) Co.,Ltd.	+86-0571-88938639 +8617705817739	info@dycnchem.com	China	52705	58
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418684 +8618949823763	sales@tnjchem.com	China	25356	58

Supplier	Advantage
Hebei Yanxi Chemical Co., Ltd.	58
career henan chemical co	58
Shenzhen Nexconn Pharmatechs Ltd	58
Alchem Pharmtech,Inc.	58
Shaanxi Dideu Medichem Co. Ltd	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	58
Shanghai Yudiao Chemistry Technology Co.,Ltd	58
Career Henan Chemica Co	58
Dayang Chem (Hangzhou) Co.,Ltd.	58
Hefei TNJ Chemical Industry Co.,Ltd.	58

View Lastest Price from 3-AMINO-8-BENZYL-8-AZABICYCLO[3.2.1]OCTANE (3-EXO)- manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-12-12	8-Benzyl-8-azabicyclo[3.2.1]octane-3-exo-amino 76272-36-1	$1.00	1KG	99%	10000KG	Shaanxi Dideu Medichem Co. Ltd
2025-06-20	3-AMINO-8-BENZYL-8-AZABICYCLO[3.2.1]OCTANE (3-EXO)- 76272-36-1		1kg	0.99	20tons	Hebei Yanxi Chemical Co., Ltd.
2020-02-26	Benzyl-8-azabicyclo[3.2.1]octan-3-exo-amine 76272-36-1	$1.00	1KG	99%+	100 tons	Shaanxi Dideu Medichem Co. Ltd

8-Benzyl-8-azabicyclo[3.2.1]octane-3-exo-amino
76272-36-1
$1.00
99%
Shaanxi Dideu Medichem Co. Ltd

3-AMINO-8-BENZYL-8-AZABICYCLO[3.2.1]OCTANE (3-EXO)-
76272-36-1
$0.00
0.99
Hebei Yanxi Chemical Co., Ltd.

Benzyl-8-azabicyclo[3.2.1]octan-3-exo-amine
76272-36-1
$1.00
99%+
Shaanxi Dideu Medichem Co. Ltd

3-AMINO-8-BENZYL-8-AZABICYCLO[3.2.1]OCTANE (3-EXO)- Spectrum

3-AMINO-8-BENZYL-8-AZABICYCLO[3.2.1]OCTANE (3-EXO)-(76272-36-1)¹HNMR

76272-36-1(3-AMINO-8-BENZYL-8-AZABICYCLO[3.2.1]OCTANE (3-EXO)-)Related Search:

5-Pyrimidinecarboxamide, 2-amino-N-(8-(p-fluorobenzyl)-3-beta-nortropa nyl)-4-methoxy-, monomaleate 5-Pyrimidinecarboxamide, N-(8-benzyl-3-beta-nortropanyl)-2-ethyl-4-met hoxy- 5-Pyrimidinecarboxamide, 2-amino-N-(8-benzyl-3-beta-nortropanyl)-4-met hoxy- 2-Amino-4-methoxy-N-(8-(p-nitrobenzyl)-3-beta-nortropanyl)-5-pyrimidin ecarboxamide maleate 2-Amino-4-methoxy-N-(8-(o-methylbenzyl)-3-beta-nortropanyl)-5-pyrimidi necarboxamide

5-Pyrimidinecarboxamide, N-(8-benzyl-3-beta-nortropanyl)-2-(dimethylam ino)-4-ethoxy-, monomaleate 2-Amino-N-(8-(o-fluorobenzyl)-3-beta-nortropanyl)-4-methoxy-5-pyrimidi necarboxamide 5-Pyrimidinecarboxamide, 4-methoxy-N-(8-(phenylmethyl)-8-azabicyclo(3. 2.1)oct-3-yl)-, exo- 2-Amino-N-(8-benzyl-3-beta-nortropanyl)-4-ethoxy-5-pyrimidinecarboxami de maleate 5-Pyrimidinecarboxamide, N-(8-benzyl-3-beta-nortropanyl)-2-(dimethylam ino)-4-methoxy-, monomaleate

5-Pyrimidinecarboxamide, N-(8-benzyl-3-beta-nortropanyl)-4-ethoxy-2-et hyl- 2-Amino-N-(8-(m-chlorobenzyl)-3-beta-nortropanyl)-4-methoxy-5-pyrimidi necarboxamide exo-5-Bromo-2,3-dimethoxy-N-(8-(phenylmethyl)-8-azabicyclo(3.2.1)oct-3 -yl)benzamide 5-Pyrimidinecarboxamide, 4-ethoxy-N-(8-(phenylmethyl)-8-azabicyclo(3.2 .1)oct-3-yl)-, exo- 2-Amino-N-(8-(p-chlorobenzyl)-3-beta-nortropanyl)-4-methoxy-5-pyrimidi necarboxamide

Benzamide, 4-amino-5-bromo-N-(8-((3,4-dichlorophenyl)methyl)-8-azabicy clo(3.2.1)oct-3-yl)-2-methoxy-, exo- Benzamide, 4-amino-5-bromo-N-(8-((4-ethylphenyl)methyl)-8-azabicyclo(3 .2.1)oct-3-yl)-2-methoxy-, exo- 2-Amino-4-methoxy-N-(8-(p-methylbenzyl)-3-beta-nortropanyl)-5-pyrimidi necarboxamide

1of4

exo-3-ami-8-benzyl-8-azabicyclo[3.2.1]octane 3-AMINO-8-BENZYL-8-AZABICYCLO[3.2.1]OCTANE (3-EXO)- 8-Benzyl-8-azabicyclo[3.2.1]octan-3-exo-amine Benzyl-8-azabicyclo[3.2.1]octan-3-exo-amine exo-3-amino-8-benzyl-8-azabicyclo[3.2.1]octane 8-Azabicyclo[3.2.1]octan-3-amine,8-(phenylmethyl)-, (3-exo)- 8-Benzyl-8-azabicyclo[3.2.1]octane-3-exo-amino 8-benzyl-8-azabicyclo[3.2.1]octan-1-aMine (3-exo-8-(PhenylMethyl)-8-azabicyclo[3.2.1]octan-3-aMine (exo-8-Benzyl-8-azabicyclo[3.2.1]oct-3-yl)aMine exo-8-Benzyl-8-azabicyclo[3.2.1]octan-3-aMine (1R,3s,5S)-8-benzyl-8-azabicyclo[3.2.1]octan-3-amine 8-Benzyl-8-azabycyclo (3.2.1)octan-3-amine (3-exo)-8-(Phenylmethyl)-8-azabicyclo [3.2.1]octan- 3-amine Fumarate salt (1R,3r,5S)-8-benzyl-8-azabicyclo[3.2.1]octan-3-amine (3-Exo)-8-Benzyl-8-aza-bicyclo[3.2.1]oct-3-ylamine exo-3-Amino-8-benzyl-8-azabicyclo[3.2.1]octane - [A14384] Rel-(1r,3s,5s)-8-benzyl-8-azabicyclo[3.2.1]octan-3-amine exo-8-benzyl-8-azabiscyclo[3.2.1]octyl-3-amine 76272-36-1 Amines Aromatics Heterocycles Intermediates & Fine Chemicals Pharmaceuticals