3,4-Dichlorophenylboronic acid
- CAS No.
- 151169-75-4
- Chemical Name:
- 3,4-Dichlorophenylboronic acid
- Synonyms
- Boronic acid, B-(3,4-dichlorophenyl)-;AKOS BRN-0087;RARECHEM AH PB 0086;3,4-Dichlorophenylbo;3,4-dichlorobenboronic acid;3,4-dichlophenylboronic acid;3,4-Dichlorophenylboronicaci;3,4-DICHLOROPHENYLBORNIC ACID;3,4-DICHLOROPHENYLBORONIC ACID;3,4-DICHLOROBENZENEBORONIC ACID
- CBNumber:
- CB4158699
- Molecular Formula:
- C6H5BCl2O2
- Molecular Weight:
- 190.82
- MDL Number:
- MFCD01074646
- MOL File:
- 151169-75-4.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 280-285 °C (lit.) |
|---|---|
| Boiling point | 339.2±52.0 °C(Predicted) |
| Density | 1.47±0.1 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | Acetone (Slightly), Chloroform (Very Slightly, Heated, Sonicated) |
| pka | 7.37±0.10(Predicted) |
| form | Powder |
| color | White to off-white |
| BRN | 7369790 |
| InChI | InChI=1S/C6H5BCl2O2/c8-5-2-1-4(7(10)11)3-6(5)9/h1-3,10-11H |
| InChIKey | JKIGHOARKAIPJI-UHFFFAOYSA-N |
| SMILES | B(C1=CC=C(Cl)C(Cl)=C1)(O)O |
| CAS DataBase Reference | 151169-75-4(CAS DataBase Reference) |
| UNSPSC Code | 12352103 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xi,F | |||||||||
| Risk Statements | 36/37/38-19-11 | |||||||||
| Safety Statements | 26-36-37/39-33-16 | |||||||||
| WGK Germany | 3 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29163990 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
|||||||||
| NFPA 704 |
|
3,4-Dichlorophenylboronic acid price More Price(70)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 471917 | 3,4-Dichlorophenylboronic acid ≥95% | 151169-75-4 | 5g | $64.5 | 2026-04-30 | Buy |
| Sigma-Aldrich | 471917 | 3,4-Dichlorophenylboronic acid ≥95% | 151169-75-4 | 25g | $91.4 | 2026-04-30 | Buy |
| TCI Chemical | D3783 | 3,4-Dichlorophenylboronic Acid (contains varying amounts of Anhydride) | 151169-75-4 | 5g | $54 | 2026-04-30 | Buy |
| TCI Chemical | D3783 | 3,4-Dichlorophenylboronic Acid (contains varying amounts of Anhydride) | 151169-75-4 | 25g | $174 | 2026-04-30 | Buy |
| TRC | TRC-D436555-5G | 3,4-Dichlorophenylboronic Acid | 151169-75-4 | 5g | $91 | 2026-06-03 | Buy |
3,4-Dichlorophenylboronic acid Chemical Properties, Uses, Production
Chemical Properties
white to off-white powder
Uses
suzuki reaction
Uses
3,4-Dichlorophenylboronic Acid is a reactant used in the synthesis of 2-(3-fluoro-4-methylsulfonylaminophenyl)propanamides as hTRPV1 antagonists.
Synthesis
67-56-1
55124-35-1
18282-59-2
151169-75-4
GENERAL PROCEDURE: A 1 M solution (375 μL, 375 μmol) of phenylmagnesium bromide (PhMgBr) THF (375 μL, 375 μmol) was added dropwise to a solution of diisopropylaminoborane (DIPAB, 863 mg, 7.5 mmol) and magnesium shavings (182 mg, 7.5 mmol) in tetrahydrofuran (THF, 4 mL) under nitrogen protection at room temperature. After 10 min of reaction, 30 mL of anhydrous THF was added, followed by 4-bromo-1,2-dichlorobenzene (5 mmol). The reaction mixture was cooled to 0 °C and quenched by slow addition of methanol (7 mL). After 1 h of reaction, the volatile solvent was removed by distillation under reduced pressure and the resulting solid was dissolved in a 1 N hydrochloric acid/methanol (7:3, v/v) mixture. After stirring at room temperature for 1 h, ethyl acetate (100 mL) was added for extraction, and the organic phase was washed sequentially with 1 N hydrochloric acid (30 mL) and saturated saline (3 x 30 mL). The organic phase was concentrated under reduced pressure to give the crude product, which was purified by recrystallization from water (H2O) to give the target product 3,4-dichlorophenylboronic acid.
References
[1] Tetrahedron, 2019, vol. 75, # 2, p. 164 - 171
3,4-Dichlorophenylboronic acid Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| SHANGHAI BANGCHENG CHEMICAL Co.,Ltd. | 021-69106960 13701823997 | 13701823733@163.com | China | 4634 | 60 |
| Shanghai Boyle Chemical Co., Ltd. | 021-50182298 021-50180596 | sales@boylechem.com | China | 2202 | 55 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| INTATRADE GmbH | +49 3493/605464 | sales@intatrade.de | Germany | 3563 | 66 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| ShangHai DEMO Chemical Co.,Ltd | 400-021-7337 2355568890 | sales@demochem.com | China | 2569 | 57 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 |
View Latest Price from 3,4-Dichlorophenylboronic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-02 | 3,4-Dichlorophenylboronic acid
151169-75-4
|
$1.20-34.00 | 1kg | 99% | Henan Fengda Chemical Co., Ltd | ||
 |
2022-09-28 | 3,4-Dichlorophenylboronic acid
151169-75-4
|
$28.00-30.00 | 1000Kg | 99.0% up | 50 tons per month | Xinxiang Hongqi District Houyuan Trading Co.,Ltd | |
 |
2022-02-09 | 3,4-Dichlorophenylboronic acid
151169-75-4
|
1KG | 99.1% | 100 tons | Honest Joy Holdings Limited |
-
- 3,4-Dichlorophenylboronic acid
151169-75-4
- $1.20-34.00
- 99%
- Henan Fengda Chemical Co., Ltd
-
- 3,4-Dichlorophenylboronic acid
151169-75-4
- $28.00-30.00
- 99.0% up
- Xinxiang Hongqi District Houyuan Trading Co.,Ltd
-
- 3,4-Dichlorophenylboronic acid
151169-75-4
- $0.00
- 99.1%
- Honest Joy Holdings Limited
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