2,5-Dimethylphenylboronic acid
- CAS No.
- 85199-06-0
- Chemical Name:
- 2,5-Dimethylphenylboronic acid
- Synonyms
- AKOS BRN-0066;AKOS BRN-0086;2-Borono-p-xylene;CHEMBRDG-BB 4003297;RARECHEM AH PB 0196;RARECHEM AH PB 0089;p-Xyleneboronic acid;P-XYLENE-2-BORONIC ACID;2,5-DIMETHYLPHENYLBORONIC ACID;2,5-DIMETHYLBENZENEBORONIC ACID
- CBNumber:
- CB7696062
- Molecular Formula:
- C8H11BO2
- Molecular Weight:
- 149.98
- MDL Number:
- MFCD01863525
- MOL File:
- 85199-06-0.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 186-191 °C (lit.) |
|---|---|
| Boiling point | 305.1±52.0 °C(Predicted) |
| Density | 1.07±0.1 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| pka | 8.70±0.58(Predicted) |
| form | Solid |
| color | White |
| BRN | 3241785 |
| InChI | 1S/C8H11BO2/c1-6-3-4-7(2)8(5-6)9(10)11/h3-5,10-11H,1-2H3 |
| InChIKey | OOMZKLJLVGQZGV-UHFFFAOYSA-N |
| SMILES | Cc1ccc(C)c(c1)B(O)O |
| CAS DataBase Reference | 85199-06-0(CAS DataBase Reference) |
| UNSPSC Code | 12352103 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| PPE | Eyeshields, Gloves, type N95 (US) | |||||||||
| Hazard Codes | Xn,Xi | |||||||||
| Risk Statements | 36/37/38-22 | |||||||||
| Safety Statements | 37/39-26-36/37 | |||||||||
| WGK Germany | 3 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29163990 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| NFPA 704 |
|
2,5-Dimethylphenylboronic acid price More Price(75)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 483516 | 2,5-Dimethylphenylboronic acid | 85199-06-0 | 5g | $107 | 2023-06-20 | Buy |
| Sigma-Aldrich | 483516 | 2,5-Dimethylphenylboronic acid | 85199-06-0 | 25g | $468 | 2023-06-20 | Buy |
| TCI Chemical | D3517 | 2,5-Dimethylphenylboronic Acid (contains varying amounts of Anhydride) | 85199-06-0 | 1g | $23 | 2026-04-30 | Buy |
| TCI Chemical | D3517 | 2,5-Dimethylphenylboronic Acid (contains varying amounts of Anhydride) | 85199-06-0 | 5g | $51 | 2026-04-30 | Buy |
| TRC | TRC-D473245-5G | (2,5-Dimethylphenyl)boronic Acid | 85199-06-0 | 5g | $108 | 2026-06-03 | Buy |
2,5-Dimethylphenylboronic acid Chemical Properties, Uses, Production
Chemical Properties
white to light yellow crystal powde
Uses
Reactant for:• ;Friedel-Crafts alkylation1• ;Suzuki-Miyaura coupling2
Uses
suzuki reaction
Uses
Reactant for:
- Friedel-Crafts alkylation
- Suzuki-Miyaura coupling
Synthesis
121-43-7
553-94-6
7732-18-5
85199-06-0
The general procedure for the synthesis of 2,5-dimethylphenylboronic acid from trimethyl borate, 2,5-dimethylbromobenzene and aqueous electrophoretic grade was as follows: 1-bromo-2,5-dimethylbenzene (25.0 g, 0.135 mol) was dissolved in 200 ml of tetrahydrofuran under the protection of nitrogen in a 1 L round-bottomed flask and cooled to -78 °C. A 1.6 M n-butyllithium solution was added slowly dropwise and the reaction was stirred for 2 hours keeping the temperature at -78 °C. Subsequently, trimethyl borate (18.2 g, 0.176 mol) was added dropwise and the reaction continued at the same temperature. After completion of the reaction, 1 equivalent of hydrochloric acid (101 ml, 0.162 mol) was added to acidify the reaction mixture at room temperature and stirred for 1 hour. The reaction solution was concentrated under reduced pressure and the resulting solid was recrystallized from hexane to give Intermediate 1-b (12.5 g, 62% yield).
References
[1] Patent: KR2015/52989, 2015, A. Location in patent: Paragraph 0326-0331
2,5-Dimethylphenylboronic acid Preparation Products And Raw materials
Raw materials
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Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Jia Xing Isenchem Co.,Ltd | 0573-85285100 18627885956 | isenchem@163.com | China | 9389 | 66 |
| Accela ChemBio Co.,Ltd. | 021-50795510 4000665055 | marketing@accelachem.com | China | 10972 | 64 |
| Shanghai Longsheng chemical Co.,Ltd. | 58099637 13585536065 | sales@shlschem.com | China | 9880 | 59 |
View Latest Price from 2,5-Dimethylphenylboronic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2019-07-06 | 2,5-Dimethylphenylboronic acid
85199-06-0
|
$1.00 | 1KG | 98% | 1kg,5kg,100kg | Career Henan Chemical Co |
-
- 2,5-Dimethylphenylboronic acid
85199-06-0
- $1.00
- 98%
- Career Henan Chemical Co
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