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TRANS-1-METHYL-4-CARBOXY-5-(3-PYRIDYL)-2-PYRROLIDINONE

TRANS-1-METHYL-4-CARBOXY-5-(3-PYRIDYL)-2-PYRROLIDINONE structure

CAS No.: 33224-01-0

Chemical Name:: TRANS-1-METHYL-4-CARBOXY-5-(3-PYRIDYL)-2-PYRROLIDINONE

Synonyms: TRANS-4-COTININECARBOXYLIC ACID;CARBOXY COTININE;TIMTEC-BB SBB003355;TRANS-4'-CARBOXYCOTININE;trans-4-Cotininecarboxylic acid 97%;trans-4-Cotininecarboxylic acid;TRANS-1-METHYL-4-CARBOXY-5-(3-PYRIDYL)-2-PYRROLIDINONE;trans-1-Methyl-4-carboxy-5-(3-pyridyl)-2-pyrrolidinone>1-Methyl-2α-(3-pyridyl)-5-oxopyrrolidine-3β-carboxylic acid;trans-1-Methyl-4-carboxy-5-(3-pyridyl)-2-pyrrolidinone

CBNumber:: CB4197492

Molecular Formula:: C11H12N2O3

Molecular Weight:: 220.23

MDL Number:: MFCD00075394

MOL File:: 33224-01-0.mol

MSDS File:: SDS

Last updated:2026-05-28 02:09:36

Product description	Number	Pack Size	Price
trans-4-Cotininecarboxylic acid 97%	347574	5g	$377
trans-1-Methyl-4-carboxy-5-(3-pyridyl)-2-pyrrolidinone >95.0%(GC)(T)	M1053	100mg	$16
trans-1-Methyl-4-carboxy-5-(3-pyridyl)-2-pyrrolidinone >95.0%(GC)(T)	M1053	1g	$54
(2S)-trans-4-Cotininecarboxylic Acid ≥97%(GC)	422219	100mg	$389
(2S)-trans-4-Cotininecarboxylic Acid ≥97%(GC)	422219	250mg	$559

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TRANS-1-METHYL-4-CARBOXY-5-(3-PYRIDYL)-2-PYRROLIDINONE Properties

Melting point	194-195 °C(lit.)
Boiling point	483.8±45.0 °C(Predicted)
Density	1.327±0.06 g/cm3(Predicted)
storage temp.	Inert atmosphere,Room Temperature
pka	3.94±0.40(Predicted)
InChI	1S/C11H12N2O3/c1-13-9(14)5-8(11(15)16)10(13)7-3-2-4-12-6-7/h2-4,6,8,10H,5H2,1H3,(H,15,16)/t8-,10+/m0/s1
InChIKey	DEYLVDCFTICBTB-WCBMZHEXSA-N
SMILES	CN1[C@@H]([C@H](CC1=O)C(O)=O)c2cccnc2
CAS DataBase Reference	33224-01-0(CAS DataBase Reference)
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H315-H319-H335
Precautionary statements	P261-P264-P271-P280-P302+P352-P305+P351+P338
target organs	Respiratory system
PPE	dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-37/39
WGK Germany	3
HS Code	2933.79.8500
Storage Class	11 - Combustible Solids
Hazard Classifications	Eye Irrit. 2 Skin Irrit. 2 STOT SE 3

TRANS-1-METHYL-4-CARBOXY-5-(3-PYRIDYL)-2-PYRROLIDINONE price More Price(20)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	347574	trans-4-Cotininecarboxylic acid 97%	33224-01-0	5g	$377	2026-04-30	Buy
TCI Chemical	M1053	trans-1-Methyl-4-carboxy-5-(3-pyridyl)-2-pyrrolidinone >95.0%(GC)(T)	33224-01-0	100mg	$16	2025-07-31	Buy
TCI Chemical	M1053	trans-1-Methyl-4-carboxy-5-(3-pyridyl)-2-pyrrolidinone >95.0%(GC)(T)	33224-01-0	1g	$54	2025-07-31	Buy
Usbiological	422219	(2S)-trans-4-Cotininecarboxylic Acid ≥97%(GC)	33224-01-0	100mg	$389	2026-06-03	Buy
Usbiological	422219	(2S)-trans-4-Cotininecarboxylic Acid ≥97%(GC)	33224-01-0	250mg	$559	2026-06-03	Buy

Product number	Packaging	Price	Buy
347574	5g	$377	Buy
M1053	100mg	$16	Buy
M1053	1g	$54	Buy
422219	100mg	$389	Buy
422219	250mg	$559	Buy

TRANS-1-METHYL-4-CARBOXY-5-(3-PYRIDYL)-2-PYRROLIDINONE Chemical Properties,Uses,Production

Chemical Properties

White Crystalline Solid

Uses

A major metabolite of nicotine in humans

Uses

trans-4-Cotininecarboxylic acid was used in the preparation of cotinine-conjugated horseradish peroxidase during immunoblot analysis. Anion of trans-4-cotininecarboxylic acid has been employed as pyridyl-carboxylate ligand in the preparation of polymeric copper(II) complex.

General Description

Carboxyl group of trans-4-cotininecarboxylic acid (carboxycotinine) can be used for chemical crosslinking.

TRANS-1-METHYL-4-CARBOXY-5-(3-PYRIDYL)-2-PYRROLIDINONE Preparation Products And Raw materials

Raw materials

Preparation Products

TRANS-1-METHYL-4-CARBOXY-5-(3-PYRIDYL)-2-PYRROLIDINONE Suppliers

Global( 56)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
CONIER CHEM AND PHARMA LIMITED		sales@conier.com	China	49906	58
career henan chemical co	+86-0371-86658258	factory@coreychem.com	China	29780	58
Dayang Chem (Hangzhou) Co.,Ltd.	+86-0571-88938639 17705817739	info@dycnchem.com	China	52693	58
Alfa Chemistry	+1-5166625404;	Info@alfa-chemistry.com	United States	20000	58
GIHI CHEMICALS CO.,LIMITED	+86-571-86217390; +8618058761490	info@gihichemicals.com	China	49859	58
HANGZHOU LEAP CHEM CO., LTD.	+86-571-87711850 +86-15355479329	market18@leapchem.com	China	43303	58
Aladdin Scientific		tp@aladdinsci.com	United States	54746	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131885	58
Mainchem Co., Ltd.	+86-0592-6210733	sale@mainchem.com	China	32288	55
J & K SCIENTIFIC LTD.	18210857532 18210857532	jkinfo@jkchemical.com	China	96815	76

Supplier	Advantage
CONIER CHEM AND PHARMA LIMITED	58
career henan chemical co	58
Dayang Chem (Hangzhou) Co.,Ltd.	58
Alfa Chemistry	58
GIHI CHEMICALS CO.,LIMITED	58
HANGZHOU LEAP CHEM CO., LTD.	58
Aladdin Scientific	58
Amadis Chemical Company Limited	58
Mainchem Co., Ltd.	55
J & K SCIENTIFIC LTD.	76

View Lastest Price from TRANS-1-METHYL-4-CARBOXY-5-(3-PYRIDYL)-2-PYRROLIDINONE manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2020-01-03	TRANS-1-METHYL-4-CARBOXY-5-(3-PYRIDYL)-2-PYRROLIDINONE 33224-01-0	$6.60	1KG	97%-99%	1kg -1000kg	Career Henan Chemical Co

TRANS-1-METHYL-4-CARBOXY-5-(3-PYRIDYL)-2-PYRROLIDINONE
33224-01-0
$6.60
97%-99%
Career Henan Chemical Co

TRANS-1-METHYL-4-CARBOXY-5-(3-PYRIDYL)-2-PYRROLIDINONE Spectrum

TRANS-1-METHYL-4-CARBOXY-5-(3-PYRIDYL)-2-PYRROLIDINONE(33224-01-0)¹HNMR TRANS-1-METHYL-4-CARBOXY-5-(3-PYRIDYL)-2-PYRROLIDINONE(33224-01-0)Raman TRANS-1-METHYL-4-CARBOXY-5-(3-PYRIDYL)-2-PYRROLIDINONE(33224-01-0)IR

33224-01-0(TRANS-1-METHYL-4-CARBOXY-5-(3-PYRIDYL)-2-PYRROLIDINONE)Related Search:

rac trans-4-Cotininecarboxylic Acid 3-Pyrrolidinecarboxylic acid, 1-ethyl-5-oxo-2-(3-pyridinyl)- 3-Pyrrolidinecarboxylic acid, 1-ethyl-5-oxo-2-(3-pyridinyl)-, (2S,3S)- 3-Pyrrolidinecarboxylic acid, 1-ethyl-5-oxo-2-(3-pyridinyl)-, methyl ester 3-Pyrrolidinecarboxylic acid, 1-ethyl-5-oxo-2-(3-pyridinyl)-, methyl ester, (2S,3S)-

3-Pyrrolidinecarboxamide, 1-methyl-5-oxo-2-(3-pyridinyl)-

1of2

trans-4-Cotininecarboxylic acid 97% trans-1-Methyl-4-carboxy-5-(3-pyridyl)-2-pyrrolidinone (2S,3S)-1-Methyl-5-oxo-2-(pyridin-3-yl)pyrrolidine-3-carboxylic acid TIMTEC-BB SBB003355 TRANS-1-METHYL-2-(3-PYRIDYL)PYRROLIDIN-5-ONE-3-CARBOXYLIC ACID TRANS-1-METHYL-4-CARBOXY-5-(3-PYRIDYL)-2-PYRROLIDINONE TRANS-4'-CARBOXYCOTININE CARBOXY COTININE (2S)-1-Methyl-5-oxo-2-(3-pyridinyl)-3β-pyrrolidinecarboxylic acid (2S)-5-Oxo-1-methyl-2α-(3-pyridyl)pyrrolidine-3β-carboxylic acid 1-Methyl-2α-(3-pyridyl)-5-oxopyrrolidine-3β-carboxylic acid 3-Pyrrolidinecarboxylicacid, 1-methyl-5-oxo-2-(3-pyridinyl)-, (2S,3S)- (2S,3R)-1-methyl-5-oxo-2-(pyridin-3-yl)pyrrolidine-3-carboxylic acid trans-1-Methyl-4-carboxy-5-(3-pyridyl)-2-pyrrolidinone> trans-4-Cotininecarboxylic acid TRANS-4-COTININECARBOXYLIC ACID 33224-01-0 Heterocyclic Building Blocks Pyridines Building Blocks C9 to C46 Building Blocks C11 Chemical Synthesis Heterocyclic Building Blocks Nicotine Derivatives C9 to C46 Heterocyclic Building Blocks Pyridines