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ChemicalBook >> CAS DataBase List >>N-[3,5-bis(trifluoromethyl)phenyl]-N-(1,1-dioxido-1,2-benzisothiazol-3-yl)amine

N-[3,5-bis(trifluoromethyl)phenyl]-N-(1,1-dioxido-1,2-benzisothiazol-3-yl)amine

N-[3,5-bis(trifluoromethyl)phenyl]-N-(1,1-dioxido-1,2-benzisothiazol-3-yl)amine Structure
N-[3,5-bis(trifluoromethyl)phenyl]-N-(1,1-dioxido-1,2-benzisothiazol-3-yl)amine structure
CAS No.
823830-85-9
Chemical Name:
N-[3,5-bis(trifluoromethyl)phenyl]-N-(1,1-dioxido-1,2-benzisothiazol-3-yl)amine
Synonyms
3-((3,5-Bis(trifluoromethyl)phenyl)amino)benzo[d]isothiazole 1,1-dioxide;M1002, 10 mM in DMSO;N-[3,5-bis(trifluoromethyl)phenyl]-1,2-benzothiazol-3-amine 1,1-dioxide;1,2-Benzisothiazol-3-amine, N-[3,5-bis(trifluoromethyl)phenyl]-, 1,1-dioxide;N-[3,5-bis(trifluoromethyl)phenyl]-N-(1,1-dioxido-1,2-benzisothiazol-3-yl)amine
CBNumber:
CB42008352
Molecular Formula:
C15H8F6N2O2S
Molecular Weight:
394.29
MDL Number:
MOL File:
823830-85-9.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 02:11:22
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N-[3,5-bis(trifluoromethyl)phenyl]-N-(1,1-dioxido-1,2-benzisothiazol-3-yl)amine Properties

Boiling point 414.6±55.0 °C(Predicted)
Density 1.60±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
form Solid
pka -2.13±0.20(Predicted)
color White to off-white

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319
Precautionary statements  P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

N-[3,5-bis(trifluoromethyl)phenyl]-N-(1,1-dioxido-1,2-benzisothiazol-3-yl)amine price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0182885 M1002 99.69% 823830-85-9 5mg $141 2026-06-04 Buy
ChemScene CS-0182885 M1002 99.69% 823830-85-9 10mg $211 2026-06-04 Buy
ChemScene CS-0182885 M1002 99.69% 823830-85-9 25mg $422 2026-06-04 Buy
ChemScene CS-0182885 M1002 99.69% 823830-85-9 50mg $634 2026-06-04 Buy
ChemScene CS-0182885 M1002 99.69% 823830-85-9 100mg $950 2026-06-04 Buy
Product number Packaging Price Buy
CS-0182885 5mg $141 Buy
CS-0182885 10mg $211 Buy
CS-0182885 25mg $422 Buy
CS-0182885 50mg $634 Buy
CS-0182885 100mg $950 Buy

N-[3,5-bis(trifluoromethyl)phenyl]-N-(1,1-dioxido-1,2-benzisothiazol-3-yl)amine Chemical Properties, Uses, Production

Uses

M1002 is a hypoxia-inducible factor-2 (HIF-2) agonist, and can enhance the expression of HIF-2 target genes. M1002 shows synergy with prolyl-hydroxylase domain (PHD) inhibitors[1].

Biological Activity

M1002 is a hypoxia-inducible factor-2 (HIF-2) agonist, and can enhance the expression of HIF-2 target genes. M1002 shows synergy with prolyl-hydroxylase domain (PHD) inhibitors[1]. M1002 (10 μM; 24 h) enhances the expression of HIF-2 target genes with great efficacy[1].M1002 (5 μM; 24 h) treatment shows synergy with prolyl hydroxylase domain (PHD) inhibitors[1].

References

[1]. Dalei Wu, et al. Bidirectional modulation of HIF-2 activity through chemical ligands. Nat Chem Biol. 2019 Apr;15(4):367-376.

N-[3,5-bis(trifluoromethyl)phenyl]-N-(1,1-dioxido-1,2-benzisothiazol-3-yl)amine Preparation Products And Raw materials

Raw materials

Preparation Products

N-[3,5-bis(trifluoromethyl)phenyl]-N-(1,1-dioxido-1,2-benzisothiazol-3-yl)amine Suppliers

Global Suppliers ( 13)
Supplier Tel Email Country ProdList Advantage
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9799 58
Hubei wei shi reagent group ltd., company 027-59102966 18717199209 2853877583@qq.com China 2896 58
Bide Pharmatech Ltd. 400-1647117 13681763483 product02@bidepharm.com China 59929 58
TargetMol Chemicals Inc. 4008200310 15002144251 marketing@tsbiochem.com China 24951 58
Suzhou Zhixin Biotechnology Co., Ltd. 0512-65118909 18100677375 sales@szzxbio.com China 1129 58
Nantong QuanYi Biotechnology Co., Ltd 0513-66337626 18051384581 sales@chemhifuture.com China 5985 58
Shanghai Anbida Biotechnology Co., Ltd. 021-61629020 18201956406 sales@ambeed.cn China 7032 58
Supplier Advantage
Shanghai EFE Biological Technology Co., Ltd. 58
Hubei wei shi reagent group ltd., company 58
Bide Pharmatech Ltd. 58
TargetMol Chemicals Inc. 58
Suzhou Zhixin Biotechnology Co., Ltd. 58
Nantong QuanYi Biotechnology Co., Ltd 58
Shanghai Anbida Biotechnology Co., Ltd. 58

N-[3,5-bis(trifluoromethyl)phenyl]-N-(1,1-dioxido-1,2-benzisothiazol-3-yl)amine Spectrum

N-[3,5-bis(trifluoromethyl)phenyl]-N-(1,1-dioxido-1,2-benzisothiazol-3-yl)amine(823830-85-9)1HNMR

823830-85-9 (N-[3,5-bis(trifluoromethyl)phenyl]-N-(1,1-dioxido-1,2-benzisothiazol-3-yl)amine) Related Search:

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N-[3,5-bis(trifluoromethyl)phenyl]-N-(1,1-dioxido-1,2-benzisothiazol-3-yl)amine N-[3,5-bis(trifluoromethyl)phenyl]-1,2-benzothiazol-3-amine 1,1-dioxide 1,2-Benzisothiazol-3-amine, N-[3,5-bis(trifluoromethyl)phenyl]-, 1,1-dioxide M1002, 10 mM in DMSO 3-((3,5-Bis(trifluoromethyl)phenyl)amino)benzo[d]isothiazole 1,1-dioxide 823830-85-9 C15H8F6N2O2S