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2-Hydroxy-4-methyl-benzonitrile

CAS No.
18495-14-2
Chemical Name:
2-Hydroxy-4-methyl-benzonitrile
Synonyms
2-Hydroxy-4-methyk-benzonitrile;2-Hydroxy-4-methyl-benzonitrile;Benzonitrile, 2-hydroxy-4-Methyl-
CBNumber:
CB4208996
Molecular Formula:
C8H7NO
Molecular Weight:
133.15
MDL Number:
MFCD02261941
MOL File:
18495-14-2.mol
MSDS File:
SDS
Last updated:2026-09-12 18:52:33

2-Hydroxy-4-methyl-benzonitrile Properties

Melting point 87 °C
Boiling point 286.0±28.0 °C(Predicted)
Density 1.17±0.1 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
pka 7.28±0.10(Predicted)
Appearance Light brown to yellow Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
HS Code  2926907090

2-Hydroxy-4-methyl-benzonitrile price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Activate Scientific AS33729 2-Hydroxy-4-methylbenzonitrile 98% 18495-14-2 1g $34 2026-06-04 Buy
Activate Scientific AS33729 2-Hydroxy-4-methylbenzonitrile 98% 18495-14-2 5g $75 2026-06-04 Buy
Activate Scientific AS33729 2-Hydroxy-4-methylbenzonitrile 98% 18495-14-2 25g $232 2026-06-04 Buy
Activate Scientific AS33729 2-Hydroxy-4-methylbenzonitrile 98% 18495-14-2 100g $888 2026-06-04 Buy
Matrix Scientific 074093 2-Hydroxy-4-methylbenzonitrile 18495-14-2 1.00g $462 2026-05-18 Buy
Product number Packaging Price Buy
AS33729 1g $34 Buy
AS33729 5g $75 Buy
AS33729 25g $232 Buy
AS33729 100g $888 Buy
074093 1.00g $462 Buy

2-Hydroxy-4-methyl-benzonitrile Chemical Properties, Uses, Production

Synthesis

Benzaldehyde, 2-hydroxy-4-methyl-, oxime

84159-60-4

2-HYDROXY-4-METHYL-BENZONITRILE

18495-14-2

2-Hydroxy-4-methylbenzaldehyde oxime (23 g) was added to 190 mL of acetic anhydride. The reaction mixture was heated to reflux for 2 hours. After completion of the reaction, the mixture was concentrated and the residue was poured into ice water. The aqueous phase was extracted with ethyl acetate and the organic phase was combined. The organic phase was dried over anhydrous sodium sulfate, concentrated, and separated and purified by silica gel column chromatography to finally obtain 2-hydroxy-4-methylbenzonitrile (16 g).

References

[1] Journal of the Chemical Society, 1949, p. 885,889
[2] Patent: CN108117510, 2018, A. Location in patent: Paragraph 0020; 0023; 0024

2-Hydroxy-4-methyl-benzonitrile Preparation Products And Raw materials

Raw materials

Preparation Products

Global Suppliers ( 73)
Supplier Tel Email Country ProdList Advantage
3B Pharmachem (Wuhan) International Co.,Ltd. 18930552037 3bsc@sina.com China 15813 69
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Shanghai Sunway Pharmaceutical Technology Co., Ltd 13761987713 hxzheng@sunwaypharm.cn China 8663 57
Hunan Hui Bai Shi Biotechnology Co., Ltd. 0731-85526065 13308475853 ivy@hnhbsj.com China 7236 62
Shanghai Topbiochem Technology Co., Ltd +86-21-60341587 sales@topbiochem.com China 6166 58
9ding chemical ( Shanghai) Limited 4009209199 sales@9dingchem.com China 18201 56
Tianjin Ji Ping Jia Chemical Co., Ltd. 18622448868 jpjchem@163.com China 498 62
HBCChem, Inc. +1-510-219-6317 sales@hbcchem.com United States 10628 60
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60
Hangzhou J&H Chemical Co., Ltd. 0571-87396432 sales@jhechem.com China 14905 59

2-Hydroxy-4-methyl-benzonitrile Spectrum

2-Hydroxy-4-methyk-benzonitrile Benzonitrile, 2-hydroxy-4-Methyl- 2-Hydroxy-4-methyl-benzonitrile 18495-14-2 Aromatic Nitriles