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(S)-1-Boc-2,3-dihydro-2-pyrrolecarboxylic acid ethyl ester

(S)-1-Boc-2,3-dihydro-2-pyrrolecarboxylic acid ethyl ester structure

CAS No.: 178172-26-4

Chemical Name:: (S)-1-Boc-2,3-dihydro-2-pyrrolecarboxylic acid ethyl ester

Synonyms: Ethyl N-Boc-L-proline-4-ene;(S)-1-tert-Butyl 2-ethyl 2,3-dihydro-1H-pyrrole-1,2-dicarboxylate;1-tert-butyl 2-ethyl (2S)-2,3-dihydro-1H-pyrrole-1,2-dicarboxylate;Saxagliptin Impurity 51;Saxagliptin Intermediate 1;ethyl N- Boc- 4,5- dehydroprolinate;Ethyl (S)-1-Boc-2,3-dihydro-2-pyrrolecarboxylate;(S)-1-Boc-2,3-dihydro-2-pyrrolecarboxylic acid ethyl ester;1-tert-butyl 2-ethyl (2S)-2,3-dihydro-1H-pyrrole-1,2-dicarbo...;1-O-tert-butyl 2-O-ethyl (2S)-2,3-dihydropyrrole-1,2-dicarboxylate

CBNumber:: CB42105673

Molecular Formula:: C12H19NO4

Molecular Weight:: 241.28

MDL Number:: MFCD11501326

MOL File:: 178172-26-4.mol

MSDS File:: SDS

Last updated:2026-05-28 02:01:40

Product description	Number	Pack Size	Price
ETHYL N-BOC-L-PROLINE-4-ENE 97%	60804	0.25G	$99
ETHYL N-BOC-L-PROLINE-4-ENE 97%	60804	1G	$299
ETHYL N-BOC-L-PROLINE-4-ENE 97%	60804	5G	$922
(S)-1-tert-Butyl 2-ethyl 2,3-dihydro-1H-pyrrole-1,2-dicarboxylate	153100	1.00g	$370
(S)-1-tert-Butyl 2-ethyl 2,3-dihydro-1H-pyrrole-1,2-dicarboxylate	153100	5.00g	$1110
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(S)-1-Boc-2,3-dihydro-2-pyrrolecarboxylic acid ethyl ester Properties

Boiling point	315.6±42.0 °C(Predicted)
Density	1.125±0.06 g/cm3(Predicted)
storage temp.	2-8°C
pka	-2.52±0.40(Predicted)
Appearance	Colorless to light yellow Liquid
InChI	InChI=1S/C12H19NO4/c1-5-16-10(14)9-7-6-8-13(9)11(15)17-12(2,3)4/h6,8-9H,5,7H2,1-4H3/t9-/m0/s1
InChIKey	AZVLZXHTXUIWRZ-VIFPVBQESA-N
SMILES	N1(C(OC(C)(C)C)=O)C=CC[C@H]1C(OCC)=O

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P305+P351+P338

(S)-1-Boc-2,3-dihydro-2-pyrrolecarboxylic acid ethyl ester price More Price(40)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
AstaTech	60804	ETHYL N-BOC-L-PROLINE-4-ENE 97%	178172-26-4	0.25G	$99	2026-04-30	Buy
AstaTech	60804	ETHYL N-BOC-L-PROLINE-4-ENE 97%	178172-26-4	1G	$299	2026-04-30	Buy
AstaTech	60804	ETHYL N-BOC-L-PROLINE-4-ENE 97%	178172-26-4	5G	$922	2026-04-30	Buy
Matrix Scientific	153100	(S)-1-tert-Butyl 2-ethyl 2,3-dihydro-1H-pyrrole-1,2-dicarboxylate	178172-26-4	1.00g	$370	2026-05-18	Buy
Matrix Scientific	153100	(S)-1-tert-Butyl 2-ethyl 2,3-dihydro-1H-pyrrole-1,2-dicarboxylate	178172-26-4	5.00g	$1110	2026-05-18	Buy

Product number	Packaging	Price	Buy
60804	0.25G	$99	Buy
60804	1G	$299	Buy
60804	5G	$922	Buy
153100	1.00g	$370	Buy
153100	5.00g	$1110	Buy

(S)-1-Boc-2,3-dihydro-2-pyrrolecarboxylic acid ethyl ester Chemical Properties,Uses,Production

Chemical Properties

pale yelllow oily liquid

Uses

(S)-1-Boc-2,3-dihydro-2-pyrrolecarboxylic Acid is used to prepare captopril analogs as inhibitors of angiotensin converting enzyme. It is also used to prepare stereoisomers of DPP-IV inhibitor saxagliptin.

(S)-1-Boc-2,3-dihydro-2-pyrrolecarboxylic acid ethyl ester synthesis

Synthesis of (S)-1-Boc-2,3-dihydro-2-pyrrolecarboxylic acid ethyl ester from Di-tert-butyl dicarbonate

(S)-1-Boc-2,3-dihydro-2-pyrrolecarboxylic acid ethyl ester Preparation Products And Raw materials

Raw materials

Ethyl L-pyroglutamate 1,2-Pyrrolidinedicarboxylic acid, 5-Methoxy-, 1-(1,1-diMethylethyl) 2-ethyl ester, (2S)- 1,2-Pyrrolidinedicarboxylic acid, 5-hydroxy-, 1-(1,1-diMethylethyl) 2-ethyl ester, (2S)- Di-tert-butyl dicarbonate L-Pyroglutamic acid

Preparation Products

(1S,3S,5S)-2-(TERT-BUTOXYCARBONYL)-2-AZABICYCLO[3.1.0]HEXANE-3-CARBOXYLIC ACID (1S,3S,5S)-2-Azabicyclo[3.1.0]hexane-3-carboxamide methanesulfonate

(S)-1-Boc-2,3-dihydro-2-pyrrolecarboxylic acid ethyl ester Suppliers

Global( 100)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Biochempartner	0086-13720134139	candy@biochempartner.com	CHINA	965	58
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	10403	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49979	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29792	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	+8613580539051	joe@yuhengpharm.com	CHINA	21142	58
NINGBOBENKANGJS PHARMTECHCO., LTD	+8615990591583 15990591583		CHINA	2029	58
AFINE CHEMICALS LIMITED	+86-0571-85134551	sales@afinechem.com	China	15083	58
Hefei Hirisun Pharmatech Co., Ltd	+8615056975894	shawn@hirisunpharm.com	CHINA	9911	58
Dayang Chem (Hangzhou) Co.,Ltd.	+86-0571-88938639 +8617705817739	info@dycnchem.com	China	52705	58

Supplier	Advantage
Biochempartner	58
Shenzhen Nexconn Pharmatechs Ltd	58
Alchem Pharmtech,Inc.	58
CONIER CHEM AND PHARMA LIMITED	58
career henan chemical co	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	58
NINGBOBENKANGJS PHARMTECHCO., LTD	58
AFINE CHEMICALS LIMITED	58
Hefei Hirisun Pharmatech Co., Ltd	58
Dayang Chem (Hangzhou) Co.,Ltd.	58

View Lastest Price from (S)-1-Boc-2,3-dihydro-2-pyrrolecarboxylic acid ethyl ester manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2022-02-25	1-O-tert-butyl 2-O-ethyl (2S)-2,3-dihydropyrrole-1,2-dicarboxylate 178172-26-4	$4.80	1KG	98%	100KG	Hong Kong Tiansheng New Material Trading Co., Ltd
2022-02-25	(S)-1-Boc-2,3-Dihydro-2-pyrrolecarboxylic acid ethyl ester 178172-26-4	$4.80	1KG	98%	10kg	Hong Kong Tiansheng New Material Trading Co., Ltd
2022-02-25	(S)-1-Boc-2,3-Dihydro-2-pyrrolecarboxylic acid ethyl ester 178172-26-4	$4.80	1KG	98%	100KG	Hong Kong Tiansheng New Material Trading Co., Ltd

1-O-tert-butyl 2-O-ethyl (2S)-2,3-dihydropyrrole-1,2-dicarboxylate
178172-26-4
$4.80
98%
Hong Kong Tiansheng New Material Trading Co., Ltd

(S)-1-Boc-2,3-Dihydro-2-pyrrolecarboxylic acid ethyl ester
178172-26-4
$4.80
98%
Hong Kong Tiansheng New Material Trading Co., Ltd

(S)-1-Boc-2,3-Dihydro-2-pyrrolecarboxylic acid ethyl ester
178172-26-4
$4.80
98%
Hong Kong Tiansheng New Material Trading Co., Ltd

178172-26-4((S)-1-Boc-2,3-dihydro-2-pyrrolecarboxylic acid ethyl ester)Related Search:

BOC-DL-PROLINE ETHYL ESTER (1R,3S,5R)-2-AZABICYCLO[3.1.0]HEXANE-3-CARBOXAMIDE 2,2,2-TRIFLUOROACETIC ACID (1S,3R,5S)-2-tert-Butyl 3-ethyl 2-azabicyclo[3.1.0]hexane-2,3-dicarboxylate 2-Azabicyclo[3.1.0]hexane-3-carbonitrile, 2-[(2R)-2-aMino-2-(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)acetyl]-, (1R,3R,5R)- 2-Azabicyclo[3.1.0]hexane-3-carbonitrile, 2-[(2S)-2-aMino-2-tricyclo[3.3.1.13,7]dec-1-ylacetyl]-, (1S,3S,5S)-

Saxagliptin hydrochloride 1H-Pyrrole-1-carboxylic acid, 2-(aMinocarbonyl)-2,3-dihydro-, 1,1-diMethylethyl ester, (2S)- (S) - N- Boc- adamantylglycine 2-Azabicyclo[3.1.0]hexane-2,3-dicarboxylic acid, 2-(1,1-dimethylethyl) 3-ethyl ester, (1S,3S,5S)- N-Boc-L-trans-4,5-Methanoproline

(2R)-1,2-Pyrrolidinedicarboxylic acid 1-tert-butyl 2-ethyl ester (1S,3S,5S)-2-(TERT-BUTOXYCARBONYL)-2-AZABICYCLO[3.1.0]HEXANE-3-CARBOXYLIC ACID DSLXQSYLYSTVKT-ONZQNKQFSA-N 2-Azabicyclo[3.1.0]hexane-3-carbonitrile, 2-[(2R)-2-aMino-2-(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)acetyl]-, (1S,3R,5S)- AcetaMide, N-[(1S)-2-[(1S,3S,5S)-3-cyano-2-azabicyclo[3.1.0]hex-2-yl]-1-(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)-2-oxoethyl]-2,2,2-trifluoro-

Saxagliptin O-β-D-glucuronide 2-Azabicyclo[3.1.0]hexane-3-carbonitrile, 2-[(2R)-2-aMino-2-(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)acetyl]-, (1R,3S,5R)- N-Boc-L-trans-4,5-methanoproline ethyl ester

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(S)-1-Boc-2,3-dihydro-2-pyrrolecarboxylic acid ethyl ester Saxagliptin Intermediate 1 ethyl N- Boc- 4,5- dehydroprolinate 1-O-tert-butyl 2-O-ethyl (2S)-2,3-dihydropyrrole-1,2-dicarboxylate (5S)-4,5-dihydro-1H-pyrrole-1,5-dicarboxylic?acid?1-(1,1-dimethylethyl)-5-ethyl?ester 1-tert-butyl 2-ethyl (2S)-2,3-dihydro-1H-pyrrole-1,2-dicarboxylate 1-(tert-butyl) 2-ethyl (S)-2,3-dihydro-1H-pyrrole-1,2-dicarboxylate 1H-Pyrrole-1,2-dicarboxylic acid, 2,3-dihydro-, 1-(1,1-dimethylethyl) 2-ethyl ester, (2S)- Ethyl (S)-1-Boc-2,3-dihydro-2-pyrrolecarboxylate Saxagliptin Impurity 51 (S)-2,3-Dihydropyrrole-1,2-dicarboxylic acid 1-tert-butyl ester 2-ethyl ester 1-tert-butyl 2-ethyl (2S)-2,3-dihydro-1H-pyrrole-1,2-dicarbo... (S)-1-Boc-2,3-dihydro-2-pyrrolecarboxylic acid ethyl esterQ: What is (S)-1-Boc-2,3-dihydro-2-pyrrolecarboxylic acid ethyl ester Q: What is the CAS Number of (S)-1-Boc-2,3-dihydro-2-pyrrolecarboxylic acid ethyl ester Q: What is the storage condition of (S)-1-Boc-2,3-dihydro-2-pyrrolecarboxylic acid ethyl ester Q: What are the applications of (S)-1-Boc-2,3-dihydro-2-pyrrolecarboxylic acid ethyl ester (S)-1-tert-Butyl 2-ethyl 2,3-dihydro-1H-pyrrole-1,2-dicarboxylate Ethyl N-Boc-L-proline-4-ene 178172-26-4