ChemicalBook >> CAS DataBase List >>6-METHYLSALICYLIC ACID ETHYL ESTER

6-METHYLSALICYLIC ACID ETHYL ESTER

CAS No.
6555-40-4
Chemical Name:
6-METHYLSALICYLIC ACID ETHYL ESTER
Synonyms
ETHYL 2-HYDROXY-6-METHYLBENZOATE;ETHYL 6-METHYLSALICYLATE;Ethyl6-Methylsalicylate>6-Methylsalicylsureethylester;Methylsalicylicacidethylester;6-METHYLSALICYLIC ACID ETHYL ESTER;3-ethyl-2-hydroxy-6-Methylbenzoate;6-METHYLSALICYLIC ACID ETHYL ESTER 95+%;6-Methylsalicylic acid ethyl ester ,98%;2-HYDROXY-6-METHYLBENZOIC ACID ETHYL ESTER
CBNumber:
CB4222864
Molecular Formula:
C10H12O3
Molecular Weight:
180.2
MDL Number:
MFCD01194299
MOL File:
6555-40-4.mol
MSDS File:
SDS
Last updated:2026-05-28 02:29:59

6-METHYLSALICYLIC ACID ETHYL ESTER Properties

Melting point 45°C
Boiling point 85-95 °C(Press: 0.5 Torr)
Density 1.136±0.06 g/cm3(Predicted)
storage temp. Inert atmosphere,Room Temperature
form powder to crystal
pka 10.04±0.10(Predicted)
color White to Light yellow
InChI InChI=1S/C10H12O3/c1-3-13-10(12)9-7(2)5-4-6-8(9)11/h4-6,11H,3H2,1-2H3
InChIKey KWXBNUYCDMPLEQ-UHFFFAOYSA-N
SMILES C(OCC)(=O)C1=C(C)C=CC=C1O
CAS DataBase Reference 6555-40-4(CAS DataBase Reference)
UNSPSC Code 12352200

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335-H412
Precautionary statements  P261-P273-P305+P351+P338
Hazard Codes  Xn
Risk Statements  22
Safety Statements  24/25
WGK Germany  WGK 3
HS Code  29182300
Storage Class 11 - Combustible Solids
Hazard Classifications Acute Tox. 4 Oral
Eye Irrit. 2

6-METHYLSALICYLIC ACID ETHYL ESTER price More Price(57)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical M1283 Ethyl 6-Methylsalicylate >98.0%(GC) 6555-40-4 5g $168 2026-04-30 Buy
TCI Chemical M1283 Ethyl 6-Methylsalicylate >98.0%(GC) 6555-40-4 25g $505 2026-04-30 Buy
Biosynth FE15744 Ethyl 6-methylsalicylate 6555-40-4 5g $150 2026-06-04 Buy
Biosynth FE15744 Ethyl 6-methylsalicylate 6555-40-4 10g $199.5 2026-06-04 Buy
Biosynth FE15744 Ethyl 6-methylsalicylate 6555-40-4 25g $408.25 2026-06-04 Buy
Product number Packaging Price Buy
M1283 5g $168 Buy
M1283 25g $505 Buy
FE15744 5g $150 Buy
FE15744 10g $199.5 Buy
FE15744 25g $408.25 Buy

6-METHYLSALICYLIC ACID ETHYL ESTER Chemical Properties,Uses,Production

Synthesis

Crotonaldehyde

123-73-9

Ethyl 2-chloroacetoacetate

609-15-4

6-METHYLSALICYLIC ACID ETHYL ESTER

6555-40-4

Example 1 Preparation of ethyl 2-hydroxy-6-methylbenzoate: a stirred mixture of trans-2-butenal (21.0 g, 0.30 mol) and anhydrous sodium acetate (25.0 g, 0.30 mol) in glacial acetic acid was heated to reflux temperature under nitrogen protection. Ethyl 2-chloroacetoacetate (41.1 g, 95%, 0.25 mol) was added dropwise over 2.25 hours. The reaction mixture was continued to be heated at reflux temperature for 16 h. Subsequently, it was cooled to room temperature and concentrated in vacuum to give the crude product. The crude product was partitioned between ethyl acetate and water. The organic phase was diluted with hexane and washed sequentially with water and aqueous sodium bicarbonate, and finally concentrated in vacuum to afford the target product ethyl 2-hydroxy-6-methylbenzoate as an oil in a yield of 41.0 g with a purity of 71.4% (65% yield), and the product structure was confirmed by nuclear magnetic resonance (NMR) analysis.

References

[1] Patent: US6441219, 2002, B1

Global( 186)Suppliers
Supplier Tel Email Country ProdList Advantage
Changzhou Tianrui Pharmaceutical Technology Co., Ltd. 0519-85386832 13382812559 sales@cztrchem.com China 1211 56
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Jia Xing Isenchem Co.,Ltd 0573-85285100 18627885956 isenchem@163.com China 9389 66
Accela ChemBio Co.,Ltd. 021-50795510 4000665055 marketing@accelachem.com China 10972 64
Shandong Xiya Chemical Co., Ltd 13355009207 13355009207 3007715519@qq.com China 18722 57
Shanghai Ennopharm Co., Ltd. +86 (21) 6435-5022 China 4263 65
China Langchem Inc. 0086-21-58956006 China 7798 57
Tianjin heowns Biochemical Technology Co., Ltd. 400 638 7771 sales@heowns.com China 14412 57

View Lastest Price from 6-METHYLSALICYLIC ACID ETHYL ESTER manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
6-METHYLSALICYLIC ACID ETHYL ESTER pictures 2019-07-06 6-METHYLSALICYLIC ACID ETHYL ESTER
6555-40-4
$1.00 1KG 98% 200KG Career Henan Chemical Co
ETHYL 6-METHYLSALICYLATE 6-METHYLSALICYLIC ACID ETHYL ESTER 2-HYDROXY-6-METHYLBENZOIC ACID ETHYL ESTER Methylsalicylicacidethylester 6-Methylsalicylsureethylester 6-Methylsalicylic acid ethyl ester ,98% 6-METHYLSALICYLIC ACID ETHYL ESTER 95+% 3-ethyl-2-hydroxy-6-Methylbenzoate Ethyl 2-Hydroxy-6-methylbenzoate 2-Hydroxy-6-methylbenzoic Acid Ethyl Ester 6-Methylsalicylic Acid Ethyl Ester Benzoic acid, 2-hydroxy-6-Methyl-, ethyl ester Ethyl6-Methylsalicylate> ETHYL 2-HYDROXY-6-METHYLBENZOATE 6555-40-4 Aromatic Esters