4-Benzyloxy-3-methoxyacetophenone
- CAS No.
- 1835-11-6
- Chemical Name:
- 4-Benzyloxy-3-methoxyacetophenone
- Synonyms
- NSC 201234;FMX15114-A1;dopamine-002;TIMTEC-BB SBB008382;Acetovanillone benzyl ether;4-Benzyloxy-3-methoxyacetophenone;4'-Benzyloxy-3'-methoxyacetophenone;3'-Methoxy-4'-(benzyloxy)acetophenone;4’-(benzyloxy)-3’-methoxy-acetophenon;Acetophenone, 4'-(benzyloxy)-3'-methoxy-
- CBNumber:
- CB4231709
- Molecular Formula:
- C16H16O3
- Molecular Weight:
- 256.3
- MDL Number:
- MFCD00017326
- MOL File:
- 1835-11-6.mol
- MSDS File:
- SDS
| Melting point | 85-87°C |
|---|---|
| Boiling point | 396.5±27.0 °C(Predicted) |
| Density | 1.115±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Acetonitrile (Slightly), Dichloromethane (Slightly), DMSO (Slightly, Heated) |
| form | Solid |
| color | White to Off-White |
| BRN | 1885776 |
| EWG's Food Scores | 1 |
| FDA UNII | WNL24ZK4PM |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362-P403+P233-P405-P501 | |||||||||
| Safety Statements | 22-24/25 | |||||||||
| RTECS | AM5966000 | |||||||||
| NFPA 704 |
|
4-Benzyloxy-3-methoxyacetophenone price More Price(37)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | TRC-B286545-500MG | 1-(4-Benzyloxy-3-methoxyphenyl)ethanone | 1835-11-6 | 500mg | $97 | 2026-06-03 | Buy |
| TRC | TRC-B286545-250MG | 1-(4-Benzyloxy-3-methoxyphenyl)ethanone | 1835-11-6 | 250mg | $72 | 2026-06-03 | Buy |
| TRC | TRC-B286545-1G | 1-(4-Benzyloxy-3-methoxyphenyl)ethanone | 1835-11-6 | 1g | $133 | 2026-06-03 | Buy |
| Synthonix | B58683 | 1-(4-(Benzyloxy)-3-methoxyphenyl)ethanone 97% | 1835-11-6 | 1g | $15 | 2026-05-06 | Buy |
| Synthonix | B58683 | 1-(4-(Benzyloxy)-3-methoxyphenyl)ethanone 97% | 1835-11-6 | 5g | $75 | 2026-05-06 | Buy |
4-Benzyloxy-3-methoxyacetophenone Chemical Properties, Uses, Production
Chemical Properties
Pale Yellow Solid
Uses
Intermediate in the preparation of Epinephrine metabolites
Synthesis
100-39-0
498-02-2
1835-11-6
The general procedure for the synthesis of 4-benzyloxy-3-methoxyacetophenone from benzyl bromide and vanillylacetophenone was as follows: 4-hydroxy-3-methoxyacetophenone (40 g, 240 mmol), benzyl bromide (31.4 mL, 260 mmol), and potassium carbonate (99.6 g, 360 mmol) were dissolved in N,N-dimethylformamide (DMF, 800 mL) and the reaction The mixture was heated to 40 °C and stirred overnight. After completion of the reaction, the mixture was cooled to room temperature, poured into ice water and the solid product precipitated was collected by filtration. The solid product was washed with water and dried to give 1-(4-benzyloxy-3-methoxyphenyl)ethanone (61 g, 99% yield).
References
[1] Patent: WO2005/30140, 2005, A2. Location in patent: Page/Page column 198
[2] Journal of Agricultural and Food Chemistry, 2017, vol. 65, # 19, p. 3965 - 3974
[3] Patent: WO2006/108059, 2006, A1. Location in patent: Page/Page column 87
[4] Bioorganic and Medicinal Chemistry, 2002, vol. 10, # 3, p. 675 - 683
4-Benzyloxy-3-methoxyacetophenone Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| Beijing Ouhe Technology Co., Ltd | 13552068683 13522913783 | 2355560935@qq.com | China | 11777 | 60 |
| JinYan Chemicals(ShangHai) Co.,Ltd. | 13817811078 | sales@jingyan-chemical.com | China | 9963 | 60 |
| Nanjing Chemlin Chemical Co., Ltd | 025-83697070 13770331960 | info@chemlin.com.cn | China | 16305 | 64 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32273 | 50 |
| Hunan Hui Bai Shi Biotechnology Co., Ltd. | 0731-85526065 13308475853 | ivy@hnhbsj.com | China | 7236 | 62 |
| Shanghai Sphchem Co., Ltd. | 021-56491756 13512199871 | 2819742715@qq.com | China | 3994 | 55 |
| Chengdu HappySyn Pharmaceutical Technology Co., Ltd. | 85114309 18982182443 | yangli@happysyn.com | China | 2284 | 55 |
View Latest Price from 4-Benzyloxy-3-methoxyacetophenone manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2023-07-19 | 4-BENZYLOXY-3-METHOXYACETOPHENONE
1835-11-6
|
$30.00 | 1KG | 99% | 20 Tons | Wuhan wingroup Pharmaceutical Co., Ltd | |
 |
2023-03-10 | 4-BENZYLOXY-3-METHOXYACETOPHENONE
1835-11-6
|
$30.00 | 1KG | 99% | 5 Tons Per Day | Weijer International Trade (Hebei) Co., Ltd. | |
 |
2022-02-25 | 1-(4-Benzyloxy-3-Methoxyphenyl)ethanone
1835-11-6
|
1KG | 98% | 1000 | Jinan Ande Pharmaceutical Co.,Ltd. |
-
- 4-BENZYLOXY-3-METHOXYACETOPHENONE
1835-11-6
- $30.00
- 99%
- Wuhan wingroup Pharmaceutical Co., Ltd
-
- 4-BENZYLOXY-3-METHOXYACETOPHENONE
1835-11-6
- $30.00
- 99%
- Weijer International Trade (Hebei) Co., Ltd.
-
- 1-(4-Benzyloxy-3-Methoxyphenyl)ethanone
1835-11-6
- $0.00
- 98%
- Jinan Ande Pharmaceutical Co.,Ltd.
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