ChemicalBook >> CAS DataBase List >>4-Bromo-2-chloro-6-methylphenol

4-Bromo-2-chloro-6-methylphenol

CAS No.
7530-27-0
Chemical Name:
4-Bromo-2-chloro-6-methylphenol
Synonyms
4-BROMO-6-CHLORO-O-CRESOL;4-Bromo-2-chloro-6-methylphenol;2-Chloro-4-bromo-6-methylphenol;5-Bromo-3-chloro-2-hydroxytoluene;Phenol, 4-broMo-2-chloro-6-Methyl-;4-Bromo-2-chloro-6-methylphenol97%;4-Bromo-2-chloro-6-methylphenol 97%;5-Bromo-3-chloro-2-hydroxytoluene, 4-Bromo-6-chloro-o-cresol
CBNumber:
CB4236092
Molecular Formula:
C7H6BrClO
Molecular Weight:
221.48
MDL Number:
MFCD00002167
MOL File:
7530-27-0.mol
MSDS File:
SDS
Last updated:2026-09-12 18:52:39

4-Bromo-2-chloro-6-methylphenol Properties

Melting point 45 °C
Boiling point 254.0±35.0 °C(Predicted)
Density 1.674±0.06 g/cm3(Predicted)
Flash point 110°C
storage temp. Inert atmosphere,Room Temperature
pka 8.28±0.23(Predicted)
Appearance Light yellow to yellow Solid
InChI InChI=1S/C7H6BrClO/c1-4-2-5(8)3-6(9)7(4)10/h2-3,10H,1H3
InChIKey IDDUDPYBPXKGCP-UHFFFAOYSA-N
SMILES C1(O)=C(C)C=C(Br)C=C1Cl
FDA UNII V1Q03LGP5K

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P271-P280
Hazard Codes  Xi
Risk Statements  20/21/22-36/37/38
Safety Statements  22-36/37/39-37/39-26
Hazard Note  Irritant
HS Code  2907199090

4-Bromo-2-chloro-6-methylphenol price More Price(43)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Apolloscientific OR28761 4-Bromo-2-chloro-6-methylphenol 97% 7530-27-0 250mg $21 2026-06-04 Buy
Activate Scientific AS48868 4-Bromo-2-chloro-6-methylphenol 98% 7530-27-0 5g $23 2026-06-04 Buy
Activate Scientific AS48868 4-Bromo-2-chloro-6-methylphenol 98% 7530-27-0 25g $52 2026-06-04 Buy
Apolloscientific OR28761 4-Bromo-2-chloro-6-methylphenol 97% 7530-27-0 10g $115 2026-06-04 Buy
Activate Scientific AS48868 4-Bromo-2-chloro-6-methylphenol 98% 7530-27-0 100g $176 2026-06-04 Buy
Product number Packaging Price Buy
OR28761 250mg $21 Buy
AS48868 5g $23 Buy
AS48868 25g $52 Buy
OR28761 10g $115 Buy
AS48868 100g $176 Buy

4-Bromo-2-chloro-6-methylphenol Chemical Properties, Uses, Production

Synthesis

2-CHLORO-6-METHYLPHENOL

87-64-9

4-BROMO-2-CHLORO-6-METHYLPHENOL

7530-27-0

2-Chloro-6-methylphenol (5 g, 35 mmol) was used as starting material and dissolved in acetic acid (70 mL). Subsequently, N-bromosuccinimide (NBS, 6.2 g, 35 mmol) was added to this solution. The reaction mixture was stirred at room temperature for 12 hours. After completion of the reaction, the acetic acid was removed by distillation under reduced pressure. The residue was diluted with ethyl acetate, washed sequentially with saturated sodium carbonate solution and dried over sodium sulfate. Finally, the solvent was removed by reduced pressure distillation to afford the target product 4-bromo-2-chloro-6-methylphenol (4 g, 52% yield), which can be used in subsequent reactions without further purification.

References

[1] Patent: WO2017/4609, 2017, A1. Location in patent: Paragraph 0219
[2] Heterocycles, 1993, vol. 36, # 7, p. 1483 - 1488
[3] Patent: US2008/146595, 2008, A1. Location in patent: Page/Page column 24
[4] Patent: WO2017/4608, 2017, A1. Location in patent: Paragraph 0142
[5] European Journal of Medicinal Chemistry, 2017, vol. 127, p. 944 - 957

87-64-9
7530-27-0
Synthesis of 4-Bromo-2-chloro-6-methylphenol from 2-Chloro-6-methylphenol

4-Bromo-2-chloro-6-methylphenol Preparation Products And Raw materials

Raw materials

Preparation Products

Global Suppliers ( 105)
Supplier Tel Email Country ProdList Advantage
Shanghai Chengyan Pharmaceutical Technology Co., Ltd 15380089981 826519922@qq.com China 416 58
SHANGHAI FDC-CHEMICAL CO.,LTD 021-61469567 13774476675 sales@fdc-chemical.com China 10000 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Shanghai Harvest Chemical Industrial Co., Ltd. 15721252604 17321035817 sales@harvest-chem.com China 2829 64
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
China Langchem Inc. 0086-21-58956006 China 7798 57
Shanghai Sunway Pharmaceutical Technology Co., Ltd 13761987713 hxzheng@sunwaypharm.cn China 8663 57
T&W GROUP 021-61551611 13296011611 contact@trustwe.com China 9884 58
Hangzhou Sage Chemical Co., Ltd. +86057186818502 13588463833 info@sagechem.com China 10265 58
Thermo Fisher Scientific 800-810-5118 cnchemical@thermofisher.com China 17752 75

View Latest Price from 4-Bromo-2-chloro-6-methylphenol manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-BROMO-2-CHLORO-6-METHYLPHENOL pictures 2020-01-08 4-BROMO-2-CHLORO-6-METHYLPHENOL
7530-27-0
$1.00 1KG 99% 100KG Career Henan Chemical Co
4-BROMO-6-CHLORO-O-CRESOL 4-Bromo-2-chloro-6-methylphenol 97% 4-Bromo-2-chloro-6-methylphenol97% 5-Bromo-3-chloro-2-hydroxytoluene Phenol, 4-broMo-2-chloro-6-Methyl- 5-Bromo-3-chloro-2-hydroxytoluene, 4-Bromo-6-chloro-o-cresol 2-Chloro-4-bromo-6-methylphenol 4-Bromo-2-chloro-6-methylphenol 7530-27-0 ALCOHOL Phenyls & Phenyl-Het