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ChemicalBook >> CAS DataBase List >>(+/-)14(15)-Epoxy-5z,8z,11z,17z-eicosatetraenoic acid

(+/-)14(15)-Epoxy-5z,8z,11z,17z-eicosatetraenoic acid

(+/-)14(15)-Epoxy-5z,8z,11z,17z-eicosatetraenoic acid Structure
(+/-)14(15)-Epoxy-5z,8z,11z,17z-eicosatetraenoic acid structure
CAS No.
131339-24-7
Chemical Name:
(+/-)14(15)-Epoxy-5z,8z,11z,17z-eicosatetraenoic acid
Synonyms
14(15)-EPETE;RGZIXZYRGZWDMI-IXQKDQKQSA-N;14,15-EPOXY EICOSATETRAENOIC ACID;()14(15)-EpETE(solution in ethanol);(+/-)14(15)-Epoxy-5z,8z,11z,17z-eicosatetraenoic acid;5,8,11-Tridecatrienoic acid, 13-[(2R,3S)-3-(2Z)-2-penten-1-yl-2-oxiranyl]-, (5Z,8Z,11Z)-rel-
CBNumber:
CB4245957
Molecular Formula:
C20H30O3
Molecular Weight:
318.45
MDL Number:
MFCD08056091
MOL File:
131339-24-7.mol
MSDS File:
SDS
Last updated:2026-09-12 18:52:40
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(+/-)14(15)-Epoxy-5z,8z,11z,17z-eicosatetraenoic acid Properties

Boiling point 464.594±33.00 °C(Press: 760.00 Torr)(predicted)
Density 0.996±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
solubility DMF: 50 mg/ml; DMSO: 50 mg/ml; Ethanol: 50 mg/ml; PBS (pH 7.2): 1 mg/ml
pka 4.752±0.10(predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Flame (GHS02)Exclamation Mark (GHS07)
GHS02,GHS07
Signal word  Danger
Hazard statements  H225-H319
Precautionary statements  P210-P233-P240-P241-P242-P243-P264-P280-P303+P361+P353-P305+P351+P338-P337+P313-P370+P378-P403+P235-P501
NFPA 704
3
2 0

(+/-)14(15)-Epoxy-5z,8z,11z,17z-eicosatetraenoic acid price More Price(6)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 10173 (±)14(15)-EpETE ≥90% 131339-24-7 25μg $53 2026-04-30 Buy
Cayman Chemical 10173 (±)14(15)-EpETE ≥90% 131339-24-7 50μg $98 2026-04-30 Buy
Cayman Chemical 10173 (±)14(15)-EpETE ≥90% 131339-24-7 100μg $185 2026-04-30 Buy
Cayman Chemical 10173 (±)14(15)-EpETE ≥90% 131339-24-7 500μg $813 2026-04-30 Buy
ChemScene CS-0375892 14(15)-EpETE 131339-24-7 25μg $115 2026-06-04 Buy
Product number Packaging Price Buy
10173 25μg $53 Buy
10173 50μg $98 Buy
10173 100μg $185 Buy
10173 500μg $813 Buy
CS-0375892 25μg $115 Buy

(+/-)14(15)-Epoxy-5z,8z,11z,17z-eicosatetraenoic acid Chemical Properties, Uses, Production

Description

EDHF (endothelium-derived hyperpolarizing factor) is an unidentified mediator released from vascular endothelial cells in response to acetylcholine and bradykinin which is distinct from the NOS- (nitric oxide) and COX-derived (prostacyclin) vasodilators.1,2 Cytochrome P450 (CYP450) metabolism of polyunsaturated fatty acids, produces epoxides such as (±)14(15)-EpETrE which are prime candidates for the actual active mediator.3 However, the CYP450 metabolites of eicosapentaenoic acid (EPA; ) and docosahexaenoic acid (DHA; ) have been little studied relative to arachidonate epoxygenase metabolites. (±)14(15)-EpETE is the ω-3 homolog of 14(15)-EpETrE, derived via epoxidation of the 14,15-double bond of EPA. The EDHF activity of (±)14(15)-EpETE has not yet been determined.

Uses

14(15)-EpETE is the epoxide of cytochrome P450 (CYP450) and is involved in the regulation of vascular tone and renal function[1].

References

1. Chataigneau, T., Félétou, M., Duhault, J., et al. Epoxyeicosatrienoic acids, potassium channel blockers, and endothelium-dependent hyperpolarization in the guinea-pig carotid artery Br. J. Pharmacol. 123(3),574-580(1998).
2. Fisslthaler, B., Popp, R., Kiss, L., et al. Cytochrome P450 2C is an EDHF synthase in coronary arteries Nature 401(6752),493-497(1999).
3. Baron, A., Frieden, M., and Bény, J.L. Epoxyeicosatrienoic acids activate a high-conductance, Ca2+-dependent K+ channel on pig coronary artery endothelial cells J. Physiol. 504(Pt 3),537-543(1997).

(+/-)14(15)-Epoxy-5z,8z,11z,17z-eicosatetraenoic acid Preparation Products And Raw materials

Raw materials

Preparation Products

(+/-)14(15)-Epoxy-5z,8z,11z,17z-eicosatetraenoic acid Suppliers

Global Suppliers ( 32)
Supplier Tel Email Country ProdList Advantage
Yichang Zhongyitai Trading Co., Ltd. 0717-6449896 13886658719 root@zhongyitai.com China 1978 58
Alfa Chemistry 1-516-6625404 support@alfa-chemistry.com United States 9170 60
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 400-920-5774 sales@glpbio.cn China 6705 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11123 58
MedBioPharmaceutical Technology Inc 021-69568360 18916172912 order@med-bio.cn China 8137 58
amyjet 4006800868;027-59626688 18771149750 sales@amyjet.com China 2909 58
TargetMol Chemicals Inc. 4008200310 15002144251 marketing@tsbiochem.com China 24951 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11963 58
SHANGHAI ZZBIO CO., LTD. 18019219489 18901678489 tech@zzbioco.com China 12062 58
Supplier Advantage
Yichang Zhongyitai Trading Co., Ltd. 58
Alfa Chemistry 60
Shanghai Hongye Biotechnology Co. Ltd 58
TargetMol Chemicals Inc. 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58
MedBioPharmaceutical Technology Inc 58
amyjet 58
TargetMol Chemicals Inc. 58
Shanghai Yifei Biotechnology Co. , Ltd. 58
SHANGHAI ZZBIO CO., LTD. 58

View Latest Price from (+/-)14(15)-Epoxy-5z,8z,11z,17z-eicosatetraenoic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
(±)14(15)-EpETE pictures 2026-07-17 (±)14(15)-EpETE
131339-24-7
 $173.00 10g TargetMol Chemicals Inc.

131339-24-7 ((+/-)14(15)-Epoxy-5z,8z,11z,17z-eicosatetraenoic acid) Related Search:

(+/-)14(15)-Epoxy-5z,8z,11z,17z-eicosatetraenoic acid (17R,5Z,8Z,11Z,14Z)-17-Hydroxy-5,8,11,14-eicosatetraenoic acid 11(12)-EpETE (±)7(8)-EpDPA 8(9)-EpETE
(±)10(11)-EpDPA

1of2

14,15-EPOXY EICOSATETRAENOIC ACID RGZIXZYRGZWDMI-IXQKDQKQSA-N 5,8,11-Tridecatrienoic acid, 13-[(2R,3S)-3-(2Z)-2-penten-1-yl-2-oxiranyl]-, (5Z,8Z,11Z)-rel- ()14(15)-EpETE(solution in ethanol) 14(15)-EPETE (+/-)14(15)-Epoxy-5z,8z,11z,17z-eicosatetraenoic acid 131339-24-7